M
Michael A. Matthay
Researcher at University of California, San Francisco
Publications - 1063
Citations - 110857
Michael A. Matthay is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: Lung injury & Lung. The author has an hindex of 151, co-authored 998 publications receiving 98687 citations. Previous affiliations of Michael A. Matthay include University of California & Cardiovascular Institute of the South.
Papers
More filters
Journal ArticleDOI
The endogenous capacity to produce proinflammatory mediators by the ex vivo human perfused lung.
Aleksandra Leligdowicz,Aleksandra Leligdowicz,James T. Ross,Nicolas Nesseler,Michael A. Matthay +4 more
TL;DR: The ex vivo-perfused lung has a marked endogenous capacity to produce inflammatory mediators over the course of short-term perfusion that is not significantly influenced by donor lung characteristics or the presence of exogenous blood, and only minimally affected by the introduction of systemic bacteremia.
Journal ArticleDOI
Endogenous and exogenous cell-based pathways for recovery from acute respiratory distress syndrome.
TL;DR: The cellular and molecular mechanisms that damage the alveolar-capillary barrier, producing acute respiratory distress syndrome (ARDS), are summarized and the latest understanding of endogenous repair processes is discussed.
Proceedings ArticleDOI
Platelet Depletion Protects Mice in a Two-Hit Model of Transfusion-Related Acute Lung Injury (TRALI).
Journal ArticleDOI
Visualization of Fra-1/AP-1 activation during LPS-induced inflammatory lung injury using fluorescence optical imaging
Subbiah Rajasekaran,Chandramohan R. Tamatam,Haranatha R. Potteti,Venu Raman,Jae-Woo Lee,Michael A. Matthay,Dolly Mehta,Narsa M. Reddy,Sekhar P. Reddy +8 more
TL;DR: Inappropriate lung inflammatory response following oxidant and toxicant exposure can lead to abnormal repair and disease pathogenesis, including fibrosis as mentioned in this paper, and early detection of molecular and cell...
Journal ArticleDOI
Inhaled activated protein C: a novel therapy for acute lung injury?
TL;DR: It is demonstrated that inhaled APC improved oxygenation and lung aeration in a sheep model of lipopolysaccharide-induced ALI, but did not alter lung water or hemodynamics.