M
Michael A. Matthay
Researcher at University of California, San Francisco
Publications - 1063
Citations - 110857
Michael A. Matthay is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: Lung injury & Lung. The author has an hindex of 151, co-authored 998 publications receiving 98687 citations. Previous affiliations of Michael A. Matthay include University of California & Cardiovascular Institute of the South.
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Journal ArticleDOI
Beta-adrenergic receptor polymorphisms and cardiac graft function in potential organ donors.
Kiran K. Khush,Ludmila Pawlikowska,R.L. Menza,Benjamin A. Goldstein,V. Hayden,J. Nguyen,Helen Kim,Annie Poon,Anil Sapru,Michael A. Matthay,Pui-Yan Kwok,William L. Young,Lee Ann Baxter-Lowe,Jonathan G. Zaroff +13 more
TL;DR: No significant associations were found between βAR SNPs and cardiac dysfunction in 364 donors managed from 2007–2008, perhaps due to changes in donor management, lack of power in this validation cohort, or the absence of a true association.
Journal ArticleDOI
326 A Randomized Trial of Nebulized Albuterol To Enhance Resolution of Pulmonary Edema in 506 Brain Dead Organ Donors
Lorraine B. Ware,Megan Landeck,Tatsuki Koyama,E. Johnson,Gordon R. Bernard,Jae Won Lee,Michael A. Matthay +6 more
TL;DR: The use of controlled DCD lungs is associated with similar clinical outcomes as LTx using BDD donors, and led to decreased incidence of severe PGD in the DCD population.
Journal ArticleDOI
Thrombomodulin is associated with increased mortality and organ failure in mechanically ventilated children with acute respiratory failure: biomarker analysis from a multicenter randomized controlled trial.
Ana C. Monteiro,Heidi R. Flori,Mary K. Dahmer,Myung-Shin Sim,Michael W. Quasney,Martha A. Q. Curley,Michael A. Matthay,Anil Sapru +7 more
TL;DR: In this paper, the authors measured plasma sTM levels in pediatric patients with respiratory failure and found that sTM correlated with mortality and other clinical markers of poor outcomes, such as increased extrapulmonary multiorgan failure and oxygenation index (OI).
Posted ContentDOI
Impaired antibacterial immune signaling and changes in the lung microbiome precede secondary bacterial pneumonia in COVID-19
Alexandra Tsitsiklis,Beth S. Zha,Ashley Byrne,Catherine DeVoe,Sophia R. Levan,Elze Rackaityte,Sara Sunshine,Eran Mick,Rajani Ghale,Alejandra Jáuregui,Aartik Sarma,Norma F. Neff,Paula Hayakawa Serpa,Thomas Deiss,Amy L Kistler,Sidney A. Carrillo,Ansel Km,Aleksandra Leligdowicz,Stephanie A. Christenson,N. Jones,B. Wu,Darmanis S,Michael A. Matthay,Susan V. Lynch,Joseph L. DeRisi,Carolyn M. Hendrickson,Kirsten N. Kangelaris,Matthew F. Krummel,Prescott G. Woodruff,Prescott G. Woodruff,David J. Erle,David J. Erle,O. Rosenberg,Carolyn S. Calfee,Charles Langelier +34 more
TL;DR: In this article, a combination of tracheal aspirate bulk and single cell RNA sequencing (scRNA-seq) was employed to assess lower respiratory tract host immune responses and microbiome dynamics in 36 patients, including 28 COVID-19 patients, 15 of whom developed VAP, and eight critically ill controls.
Pre- and Postnatal Lung Development, Maturation, and Plasticity Distal air space epithelial fluid clearance in near-term rat fetuses is fast and requires endogenous catecholamines
Hans G. Folkesson,Michael A. Matthay,Cheryl J. Chapin,Nicolas F. M. Porta,Joseph A. Kitterman,G Hans +5 more
TL;DR: It is demonstrated that rapid rates of net alveolar fluid clearance occur late in gestation in the rat and this clearance is driven by elevations of endogenous epinephrine.