M
Michael A. Matthay
Researcher at University of California, San Francisco
Publications - 1063
Citations - 110857
Michael A. Matthay is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: Lung injury & Lung. The author has an hindex of 151, co-authored 998 publications receiving 98687 citations. Previous affiliations of Michael A. Matthay include University of California & Cardiovascular Institute of the South.
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Journal ArticleDOI
Soluble and insoluble fibronectin increases alveolar epithelial wound healing in vitro
TL;DR: It is demonstrated that alveolar epithelial wound healing can be modulated in vitro by the composition of the extracellular matrix, an effect that may be mediated by changes in cell shape.
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The acute respiratory distress syndrome following isolated severe traumatic brain injury.
Carolyn M. Hendrickson,Benjamin M. Howard,Lucy Z. Kornblith,Amanda S. Conroy,Mary F. Nelson,Hanjing Zhuo,Kathleen D. Liu,Geoffrey T. Manley,Michael A. Matthay,Carolyn S. Calfee,Mitchell J. Cohen +10 more
TL;DR: In the era of balanced hemostatic resuscitation practices, severity of head injury, male sex, early crystalloids, and early transfusion of platelets are associated with a higher risk of ARDS after severe isolated TBI.
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Early elevation of plasma von Willebrand factor antigen in pediatric acute lung injury is associated with an increased risk of death and prolonged mechanical ventilation
TL;DR: Early injury to the systemic and pulmonary endothelium, as measured by plasma vWF-Ag levels, is associated with an increased risk of death and prolonged mechanical ventilation in pediatric patients with ALI.
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Clinical trial design—effect of prone positioning on clinical outcomes in infants and children with acute respiratory distress syndrome
Martha A. Q. Curley,John H. Arnold,John E. Thompson,James C. Fackler,Mary Jo C. Grant,Lori D. Fineman,Natalie Z. Cvijanovich,Frederick E. Barr,Shirley Molitor-Kirsch,David M. Steinhorn,Michael A. Matthay,Patricia L. Hibberd +11 more
TL;DR: The process, multidisciplinary input, and procedures used to support the design of the clinical trial, as well as the challenges faced by the clinical scientists during the conduct of theclinical trial, are described.
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Alveolar Fluid Clearance in Pathologically Relevant Conditions: In Vitro and In Vivo Models of Acute Respiratory Distress Syndrome.
TL;DR: One potential therapy that targets this pathway: bone marrow-derived mesenchymal stem (stromal) cells (MSCs), based on preclinical studies, MSCs enhance AFC and promote the resolution of pulmonary edema and thus may offer a promising cell-based therapy for ARDS.