M
Michael A. Matthay
Researcher at University of California, San Francisco
Publications - 1063
Citations - 110857
Michael A. Matthay is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: Lung injury & Lung. The author has an hindex of 151, co-authored 998 publications receiving 98687 citations. Previous affiliations of Michael A. Matthay include University of California & Cardiovascular Institute of the South.
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Journal ArticleDOI
Therapeutic value of a lung protective ventilation strategy in acute lung injury.
TL;DR: The authors hypothesize that multisystem organ failure is the true cause of increased mortality from sepsis rather than the infection itself, and confirm the results of the NHLBI ARDSnet clinical trial, which reported that ventilation of acute lung injury patients with a tidal volume of 6 mL/kg of PBW reduced hospital mortality to 31%,.
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A psychometric study of the decisional conflict scale in surrogate decision makers.
Kristen E. Pecanac,Roger L. Brown,Jay S. Steingrub,Wendy G. Anderson,Michael A. Matthay,Douglas B. White +5 more
TL;DR: Overall, the DCS demonstrated good fit, and can be considered a valid and reliable tool to use with the surrogate population.
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Higher plasma cystatin C is associated with mortality after acute respiratory distress syndrome: findings from a Fluid and Catheter Treatment Trial (FACTT) substudy
Carolyn M. Hendrickson,Yuenting D. Kwong,Annika Belzer,Michael G. Shlipak,Michael G. Shlipak,Michael A. Matthay,Kathleen D. Liu +6 more
TL;DR: Higher plasma levels of cystatin C on enrollment were strongly associated with mortality at 60 days in patients with ARDS with and without AKI identified by creatinine-based definitions, indicating a better biomarker of kidney function in patients without ARDS to identify patients with multiple organ failure at higher risk of death.
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The acute respiratory distress syndrome in 2013.
TL;DR: Therapy with lung-protective ventilation and fluid conservative protocol has improved outcomes, but several new trials are in progress to test several promising strategies.
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Beyond fishing: the role of discovery proteomics in mechanistic lung research.
TL;DR: A variety of methods have been developed and refined for identifying proteins in complex biological samples, and access to these methodologies has become widespread.