Michael A. Matthay

TL;DR: A novel metagenomic sequencing-based approach that simultaneously interrogates three core elements of acute airway infections: the pathogen, lung microbiome and host response is developed and suggested to hold promise as a novel tool for LRTI diagnosis.

TL;DR: In this issue of the American Journal of Physiology-Lung Cellular and Molecular Physiology, Caruso and colleagues reprise longstanding arguments that the tobacco industry uses to cast doubt on evidence linking smoking with disease to question.

TL;DR: A retrospective study of 89 patients who developed acute respiratory failure from ARDS, 25 of whom developed criteria for ARDS in the postoperative period, found that the association between fluid administration and developing ARDS was strengthened and the type of anesthesia may be important in determining postoperative pulmonary dysfunction in higher risk patients.

TL;DR: The group suggests the use of a standard or reference MSC source to allow comparison among different cells manufactured for both preclinical and clinical studies, and suggests other approaches, such as donor pooling, an immortalized line, or self-renewing population would be satisfactory.