M
Michael A. Matthay
Researcher at University of California, San Francisco
Publications - 1063
Citations - 110857
Michael A. Matthay is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: Lung injury & Lung. The author has an hindex of 151, co-authored 998 publications receiving 98687 citations. Previous affiliations of Michael A. Matthay include University of California & Cardiovascular Institute of the South.
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Journal ArticleDOI
Neutrophils and their Fcγ receptors are essential in a mouse model of transfusion-related acute lung injury
TL;DR: In a clinically relevant in vivo mouse model of TRALI using an MHC I mAb, the mechanism of lung injury was dependent on neutrophils and their Fc gamma receptors, with prominent neutrophil sequestration in the lung microvasculature within 2 hours of administration of the mAb.
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Acute kidney injury in patients with acute lung injury: Impact of fluid accumulation on classification of acute kidney injury and associated outcomes
Kathleen D. Liu,B. Taylor Thompson,Marek Ancukiewicz,Jay S. Steingrub,Ivor S. Douglas,Michael A. Matthay,Patrick Wright,Michael W. Peterson,Peter Rock,Robert C. Hyzy,Antonio Anzueto,Jonathon D. Truwit +11 more
TL;DR: Fluid management influences serum creatinine and therefore the diagnosis of acute kidney injury using Creatinine-based definitions, and patients who have acute kidneys injury before but not after adjusting for fluid balance have lower mortality rates.
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Plasma receptor for advanced glycation end products and clinical outcomes in acute lung injury
Carolyn S. Calfee,Lorraine B. Ware,Mark D. Eisner,Polly E. Parsons,B. T. Thompson,Nancy E. Wickersham,Michael A. Matthay +6 more
TL;DR: Baseline plasma RAGE levels are strongly associated with clinical outcomes in patients with acute lung injury ventilated with higher tidal volumes, and lower tidal volume ventilation may be beneficial in part by decreasing injury to the alveolar epithelium.
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Treatment for severe acute respiratory distress syndrome from COVID-19.
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Efficacy of Low Tidal Volume Ventilation in Patients with Different Clinical Risk Factors for Acute Lung Injury and the Acute Respiratory Distress Syndrome
Mark D. Eisner,Taylor Thompson,Leonard D. Hudson,John M. Luce,Douglas Hayden,David A. Schoenfeld,Michael A. Matthay +6 more
TL;DR: There was no evidence that the efficacy of the low VT ventilation strategy differed among clinical risk factor subgroups for ALI/ARDS and controlling for demographic and clinical covariates did not appreciably affect results.