M
Michael A. Matthay
Researcher at University of California, San Francisco
Publications - 1063
Citations - 110857
Michael A. Matthay is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: Lung injury & Lung. The author has an hindex of 151, co-authored 998 publications receiving 98687 citations. Previous affiliations of Michael A. Matthay include University of California & Cardiovascular Institute of the South.
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Journal ArticleDOI
Treatment of ARDS
TL;DR: Standard supportive care for ALI/ARDS should now include a protective ventilatory strategy with low tidal volume ventilation by the protocol developed by the National Institutes of Health ARDS Network.
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Latent class analysis of ARDS subphenotypes: a secondary analysis of the statins for acutely injured lungs from sepsis (SAILS) study
Pratik Sinha,Kevin L. Delucchi,B. Taylor Thompson,Daniel F. McAuley,Daniel F. McAuley,Michael A. Matthay,Carolyn S. Calfee +6 more
TL;DR: LCA using a two-subphenotype model best described the SAILS population and validated the presence of two subphenotypes and demonstrate their utility for patient stratification in ARDS.
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Elevated plasma levels of soluble TNF receptors are associated with morbidity and mortality in patients with acute lung injury
TL;DR: Plasma levels of soluble TNF receptor I and II can serve as biomarkers for morbidity and mortality in patients with ALI and LTVV is associated with a specific decrease in sTNFRI levels, which suggests that one beneficial effect of LTVv may be to attenuate alveolar epithelial injury.
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Clinical trials in acute respiratory distress syndrome: challenges and opportunities
TL;DR: This Review focuses on future opportunities to improve clinical trial design to maximise the likelihood of identifying beneficial pharmacological therapies for acute respiratory distress syndrome and presents promising new approaches to treating ARDS.
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Alveolar epithelium: role in lung fluid balance and acute lung injury.
TL;DR: There is some experimental and clinical evidence that cAMP stimulation could accelerate the resolution of pulmonary edema in the presence of acute lung injury, and clinical trials are needed to test this potential therapeutic strategy in patients with acute lungs injury.