M
Monique G. P. van der Wijst
Researcher at University Medical Center Groningen
Publications - 29
Citations - 1235
Monique G. P. van der Wijst is an academic researcher from University Medical Center Groningen. The author has contributed to research in topics: Expression quantitative trait loci & Medicine. The author has an hindex of 14, co-authored 21 publications receiving 554 citations. Previous affiliations of Monique G. P. van der Wijst include University of California, Berkeley.
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Journal ArticleDOI
Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression
Urmo Võsa,Annique Claringbould,Annique Claringbould,Harm-Jan Westra,Marc Jan Bonder,Patrick Deelen,Biao Zeng,Holger Kirsten,Ashis Saha,Roman Kreuzhuber,Roman Kreuzhuber,Roman Kreuzhuber,Seyhan Yazar,Harm Brugge,Roy Oelen,Dylan H. de Vries,Monique G. P. van der Wijst,Silva Kasela,Natalia Pervjakova,Isabel Alves,Marie-Julie Favé,Mawusse Agbessi,Mark W. Christiansen,Rick Jansen,Ilkka Seppälä,Lin Tong,Alexander Teumer,Katharina Schramm,Gibran Hemani,Joost Verlouw,Hanieh Yaghootkar,Hanieh Yaghootkar,Hanieh Yaghootkar,Reyhan Sönmez Flitman,Reyhan Sönmez Flitman,Andrew A. Brown,Andrew A. Brown,Viktorija Kukushkina,Anette Kalnapenkis,Sina Rüeger,Eleonora Porcu,Jaanika Kronberg,Johannes Kettunen,Bernett Lee,Futao Zhang,Ting Qi,Jose Alquicira Hernandez,Wibowo Arindrarto,Frank Beutner,Peter A C 't Hoen,Joyce B. J. van Meurs,Jenny van Dongen,Maarten van Iterson,Morris A. Swertz,Julia Dmitrieva,Mahmoud Elansary,Benjamin P. Fairfax,Michel Georges,Bastiaan T. Heijmans,Alex W. Hewitt,Mika Kähönen,Yungil Kim,Yungil Kim,Julian C. Knight,Peter Kovacs,Knut Krohn,Shuang Li,Markus Loeffler,Urko M. Marigorta,Urko M. Marigorta,Hailang Mei,Yukihide Momozawa,Martina Müller-Nurasyid,Matthias Nauck,Michel G. Nivard,Brenda W.J.H. Penninx,Jonathan K. Pritchard,Olli T. Raitakari,Olli T. Raitakari,Olaf Rötzschke,Eline Slagboom,Coen D.A. Stehouwer,Michael Stumvoll,Patrick F. Sullivan,Joachim Thiery,Anke Tönjes,Jan H. Veldink,Uwe Völker,Robert Warmerdam,Cisca Wijmenga,Morris Swertz,Anand Kumar Andiappan,Grant W. Montgomery,Samuli Ripatti,Markus Perola,Zoltán Kutalik,Emmanouil T. Dermitzakis,Emmanouil T. Dermitzakis,Sven Bergmann,Sven Bergmann,Timothy M. Frayling,Holger Prokisch,Habibul Ahsan,Brandon L. Pierce,Terho Lehtimäki,Dorret I. Boomsma,Bruce M. Psaty,Sina A. Gharib,Philip Awadalla,Lili Milani,Willem H. Ouwehand,Willem H. Ouwehand,Willem H. Ouwehand,Kate Downes,Kate Downes,Oliver Stegle,Oliver Stegle,Alexis Battle,Peter M. Visscher,Jian Yang,Jian Yang,Markus Scholz,Joseph E. Powell,Joseph E. Powell,Greg Gibson,Tõnu Esko,Lude Franke +126 more
TL;DR: In this article, the authors performed cis-and trans-expression quantitative trait locus (eQTL) analyses using blood-derived expression from 31,684 individuals through the eQTLGen Consortium.
Journal ArticleDOI
The single-cell eQTLGen consortium.
Monique G. P. van der Wijst,DH de Vries,Hilde E. Groot,Gosia Trynka,CC Hon,Marc Jan Bonder,Oliver Stegle,Martijn C. Nawijn,Youssef Idaghdour,P. van der Harst,Chun Jimmie Ye,Joseph E. Powell,Fabian J. Theis,Ahmed Mahfouz,Ahmed Mahfouz,Matthias Heinig,Lude Franke +16 more
TL;DR: The sc-eQTLGen consortium is founded, aimed at pinpointing the cellular contexts in which disease-causing genetic variants affect gene expression, and provides a set of study design considerations for future single-cell eQTL studies.
Journal ArticleDOI
Type I interferon autoantibodies are associated with systemic immune alterations in patients with COVID-19.
Monique G. P. van der Wijst,Sara E. Vazquez,George C. Hartoularos,Paul Bastard,Tianna Grant,Raymund Bueno,David Lee,John R. Greenland,Yang Sun,Richard Perez,Richard Perez,Anton Ogorodnikov,Anton Ogorodnikov,Alyssa Ward,Sabrina A Mann,Kara L. Lynch,Cassandra Yun,Diane V. Havlir,Gabriel Chamie,Carina Marquez,Bryan Greenhouse,Michail S. Lionakis,Philip J. Norris,Larry J. Dumont,Kathleen Kelly,Peng Zhang,Qian Zhang,Adrian Gervais,Adrian Gervais,Tom Le Voyer,Tom Le Voyer,Alexander Whatley,Yichen Si,Ashley Byrne,Alexis J. Combes,Arjun A. Rao,Yun S. Song,Gabriela K. Fragiadakis,Kirsten N. Kangelaris,Carolyn S. Calfee,David J. Erle,Carolyn M. Hendrickson,Matthew F. Krummel,Matthew F. Krummel,Prescott G. Woodruff,Charles Langelier,Jean-Laurent Casanova,Joseph L. DeRisi,Mark S. Anderson,Chun Jimmie Ye +49 more
TL;DR: In this article, the authors found no type I IFN autoantibodies in individuals with moderate disease and no IFN-stimulated gene (ISG-I) responses in myeloid cells from patients with critical disease.
Journal ArticleDOI
Experimental mitochondria-targeted DNA methylation identifies GpC methylation, not CpG methylation, as potential regulator of mitochondrial gene expression
TL;DR: This is the first study which directly addresses the potential functionality of mtDNA methylation and unravelling the impact of mt DNA methylation adds to the understanding of the role of mitochondria in physiological and pathophysiological processes.
Journal ArticleDOI
Local chromatin microenvironment determines DNMT activity : from DNA methyltransferase to DNA demethylase or DNA dehydroxymethylase
Monique G. P. van der Wijst,Muralidhar Venkiteswaran,Hui Chen,Guoliang Xu,Torsten Plösch,Marianne G. Rots +5 more
TL;DR: It is hypothesized that the chromatin microenvironment can be locally exposed to extreme conditions, and hypothesize that such waves of extremes allow enzymes to act in differential ways.