Monique Nijhuis

TL;DR: It is shown that the rapid appearance of drug-resistant virus in serum is followed by an increase in viral RNA load, which is similar to that seen in patients treated with the reverse transcriptase inhibitor lamivudine.

TL;DR: This method simultaneously detects influenza viruses A and B in specimens of patients with respiratory infections using a TaqMan-based real-time PCR assay, which was found to be more sensitive than the combination of conventional viral culturing and shell vial culturing.

TL;DR: The evolution and fitness of viral populations appearing in a patient who received protease monotherapy indicates that the viral population in the patient does not have to represent the fittest possible variants, and thus antiretroviral therapy may drive the viral populations first through a lower fitness level and then to a higher fitness level.

TL;DR: A group of international experts to develop a scientific strategy for research towards an HIV cure summarized the group's strategy in this Perspective.

TL;DR: It is suggested that a single allogeneic HSCT with homozygous CCR5Δ32 donor cells may be sufficient to achieve HIV-1 remission with reduced intensity conditioning and no irradiation, and the findings provide further support for the development of HIV- 1 remission strategies based on preventing CCR 5 expression.