P
Patrick L. McGeer
Researcher at University of British Columbia
Publications - 569
Citations - 61292
Patrick L. McGeer is an academic researcher from University of British Columbia. The author has contributed to research in topics: Microglia & Alzheimer's disease. The author has an hindex of 122, co-authored 569 publications receiving 58584 citations. Previous affiliations of Patrick L. McGeer include Laval University & Kyoto University.
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The importance of inflammatory mechanisms in Alzheimer disease.
TL;DR: Therapeutic intervention in key inflammatory processes holds great promise for the amelioration of AD and possibly other neurodegenerative disorders.
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Choline acetyltransferase-containing neurons in rodent brain demonstrated by immunohistochemistry
TL;DR: The results provide information on the distribution of the cholinergic systems in the rostral forebrain of the rodent.
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Kainate-induced degeneration of neostriatal neurons: dependency upon corticostriatal tract.
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Neuroinflammation in Alzheimer's disease and mild cognitive impairment: a field in its infancy.
TL;DR: Recent evidence indicates that microglia can be stimulated to assume an antiinflammatory state rather than a proinflammatory state which may have therapeutic potential, and one example is hydrogen sulfide which appears to be an endogenous antiinflammatory agent.
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Human neurons generate C-reactive protein and amyloid P: upregulation in Alzheimer's disease
TL;DR: It is reported that the mRNAs and proteins of both CRP and AP are concentrated in pyramidal neurons and are upregulated in affected areas of AD brain.