P
Patrick L. McGeer
Researcher at University of British Columbia
Publications - 569
Citations - 61292
Patrick L. McGeer is an academic researcher from University of British Columbia. The author has contributed to research in topics: Microglia & Alzheimer's disease. The author has an hindex of 122, co-authored 569 publications receiving 58584 citations. Previous affiliations of Patrick L. McGeer include Laval University & Kyoto University.
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Circadian Rhythm in Pineal Tyrosine Hydroxylase
TL;DR: The results indicate a circadian rhythm with the maximum activity, at 11 p.m. to 3 a.m, similar in phase to that previously reported for melatonin and hydroxyindole-O-methyl transferase activity.
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Dendro axonic neurotransmission. II. Morphological sites for the synthesis, binding and release of neurotransmitters in dopaminergic dendrites in the substantia nigra and cholinergic dendrites in the neostriatum
TL;DR: It is hypothesized that neurotransmitters are released from dendrites as a general phenomenon in the CNS and that they can act upon axonal endings.
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Alzheimer's Disease Can Be Spared by Nonsteroidal Anti-Inflammatory Drugs
TL;DR: Widespread application of this test to detect high level controls, followed by NSAID consumption, could substantially reduce the prevalence of AD.
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Antibody production to choline acetyltransferase purified from human brain.
V.K. Singh,Patrick L. McGeer +1 more
TL;DR: The anti-CAT rabbit antibody appeared to be specific and inhibited the CAT activity on incubation, and gave a single protein band on polyacrylamide gel electrophoresis at pH 8.3 which corresponded with CAT activity.
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Separation of large DNA restriction fragments on a size-exclusion column by a nonideal mechanism.
TL;DR: The usefulness of the DuPont Bioseries GF-250 column for molecular biological manipulations is illustrated by the rapid isolation of homogeneous viral DNA fragments resected from their cloning vectors with restriction endonucleases.