P
Patrick L. McGeer
Researcher at University of British Columbia
Publications - 569
Citations - 61292
Patrick L. McGeer is an academic researcher from University of British Columbia. The author has contributed to research in topics: Microglia & Alzheimer's disease. The author has an hindex of 122, co-authored 569 publications receiving 58584 citations. Previous affiliations of Patrick L. McGeer include Laval University & Kyoto University.
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Vitronectin expression in Purkinje cells in the human cerebellum.
TL;DR: In this study, Vn immunoreactivity in Purkinje cells in the human cerebellar cortex is demonstrated and was present in sections from both neurologically normal and disease-affected cases.
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Inhibition of brain tyrosine hydroxylase by 5-halotryptophans
TL;DR: A new class of brain tyrosine hydroxylase inhibitors, the 5-halotryptophans, are described and one member of the series was compared in vivo with L-α-methyl-p-tyrosine, which significantly lowered brain and heart noradrenaline content.
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Preconditioning reduces tissue complement gene expression in the rabbit isolated heart.
Elaine J. Tanhehco,Koji Yasojima,Patrick L. McGeer,Ruth A. Washington,Kenneth S. Kilgore,Jonathon W. Homeister,Benedict R. Lucchesi +6 more
TL;DR: The results suggest that reduction of local tissue complement production may be one means by which preconditioning protects the ischemic myocardium.
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Protein labeling and biotinylation of peptides during spot synthesis using biotin p-nitrophenyl ester (biotin-ONp).
TL;DR: The results of the use biotin p‐nitrophenyl ester (biotin‐ONp) in spot synthesis and as a reagent for biotin‐labeling of protein samples are presented.
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Neurotoxic factors released by stimulated human monocytes and THP-1 cells.
TL;DR: Optimal antiinflammatory therapy may require combined suppression of these identified toxin-generating pathways as well as relatively minor pathways yet to be identified.