P
Per Ladenvall
Researcher at University of Gothenburg
Publications - 20
Citations - 1262
Per Ladenvall is an academic researcher from University of Gothenburg. The author has contributed to research in topics: Stroke & T-plasminogen activator. The author has an hindex of 13, co-authored 19 publications receiving 1156 citations. Previous affiliations of Per Ladenvall include Sahlgrenska University Hospital.
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Journal ArticleDOI
Association between C reactive protein and coronary heart disease: mendelian randomisation analysis based on individual participant data
G. Eiriksdottir,T. B. Harris,L. J. Launer,Vilmundur Gudnason,Aaron R. Folsom,Gavin Andrews,C. M. Ballantyne,Nilesh J. Samani,A. S. Hall,P. S. Braund,A. J. Balmforth,Peter H. Whincup,Richard W Morris,Debbie A Lawlor,Gordon D.O. Lowe,Nicholas J. Timpson,Shah Ebrahim,Yoav Ben-Shlomo,George Davey-Smith,Børge G. Nordestgaard,Anne Tybjærg-Hansen,Jeppe Zacho,Matthew A. Brown,Manjinder S. Sandhu,Sally L. Ricketts,Sofie Ashford,Leslie A. Lange,Alexander P. Reiner,Mary Cushman,Russel Tracy,C. Wu,J. Ge,Y. Zou,A. Sun,Joseph Hung,Brendan McQuillan,Peter L. Thompson,John Beilby,Nicole M. Warrington,Lyle J. Palmer,Christoph Wanner,Christiane Drechsler,Michael Hoffmann,F. G. R. Fowkes,Ioanna Tzoulaki,Meena Kumari,Michelle A. Miller,Michael Marmot,Charlotte Onland-Moret,Y. T. van der Schouw,J.M.A. Boer,Cisca Wijmenga,Kay-Tee Khaw,Ramachandran S. Vasan,Renate B. Schnabel,J. F. Yamamoto,E J Benjamin,Heribert Schunkert,Jeanette Erdmann,Inke R. König,Christian Hengstenberg,Benedetta D. Chiodini,MariaGrazia Franzosi,Silvia Pietri,Francesca Gori,Megan E. Rudock,Yongmei Liu,Kurt Lohman,Steve E. Humphries,Anders Hamsten,Paul Norman,Graeme J. Hankey,Konrad Jamrozik,Eric B. Rimm,J. K. Pai,Bruce M. Psaty,Susan R. Heckbert,J. C. Bis,Salim Yusuf,Sonia S. Anand,Engert Jc,C. Xie,Ryan L. Collins,Robert Clarke,David L.H. Bennett,Jaspal S. Kooner,John C. Chambers,Paul Elliott,W. März,Marcus E. Kleber,Bernhard O. Böhm,Winkelmann Br,Olle Melander,Göran Berglund,Wolfgang Koenig,Barbara Thorand,Jens Baumert,Annette Peters,JoAnn E. Manson,J.A. Cooper,P.J. Talmud,Per Ladenvall,Lovisa Johansson,J. H. Jansson,Göran Hallmans,Muredach P. Reilly,Liming Qu,Man Li,Daniel J. Rader,Hugh Watkins,Jemma C. Hopewell,Danish Saleheen,John Danesh,Philippe M. Frossard,Naveed Sattar,Michele Robertson,J. Shepherd,Ernst J. Schaefer,A. Hofman,J. C. M. Witteman,Isabella Kardys,Abbas Dehghan,U de Faire,Anna M. Bennet,Bruna Gigante,Karin Leander,Bas J M Peters,A.H. Maitland-van der Zee,A.H. De Boer,Olaf H. Klungel,Philip Greenland,J. Dai,Simin Liu,Eric J. Brunner,Mika Kivimäki,Denis St. J. O’Reilly,Ian Ford,Chris J. Packard +137 more
TL;DR: Human genetic data indicate that C reactive protein concentration itself is unlikely to be even a modest causal factor in coronary heart disease.
Journal ArticleDOI
Serum C-Reactive Protein Concentration and Genotype in Relation to Ischemic Stroke Subtype
Claes Ladenvall,Katarina Jood,Christian Blomstrand,Staffan Nilsson,Christina Jern,Per Ladenvall +5 more
TL;DR: CRP levels were significantly higher for all ischemic stroke subtypes compared with controls, both in the acute phase and at the 3-month follow-up, and Genetic variants at the CRP locus showed significant associations with CRP levels, however, neither CRP genotypes nor haplotypes showed an association to overall isChemic stroke.
Journal ArticleDOI
Fibrinolytic Gene Polymorphism and Ischemic Stroke
Katarina Jood,Per Ladenvall,Anna Tjärnlund-Wolf,Claes Ladenvall,Maria Andersson,Staffan Nilsson,Christian Blomstrand,Christina Jern +7 more
TL;DR: Neither the tPA −7351C>T nor the PAI-1 to 675 4G >5G polymorphism showed significant association with ischemic stroke, consistent with a more complex role for tPA and PAi-1 in the brain as compared with the heart.
Journal ArticleDOI
Tissue-type plasminogen activator -7,351C/T enhancer polymorphism is associated with a first myocardial infarction.
Per Ladenvall,Lars Johansson,Jan-Håkan Jansson,Sverker Jern,Torbjörn K. Nilsson,Anna Tjärnlund,Christina Jern,Kurt Boman +7 more
TL;DR: Testing the hypothesis that the tPA -7,351C/T polymorphism is associated with myocardial infarction suggests that genetic markers of local tPA release and circulating steady-state tPA levels carry independent prognostic information.
Journal ArticleDOI
Gene Polymorphism of t-PA is Associated With Forearm Vascular Release Rate of t-PA
TL;DR: Results provide the first evidence of an association between a common genetic variation at the t-PA locus and interindividual differences in net release rates of t- PA in vivo, not reflected by circulating steady-state plasma levels and can thus not be disclosed by conventional venous plasma sampling.