E
E J Benjamin
Researcher at Boston University
Publications - 9
Citations - 1153
E J Benjamin is an academic researcher from Boston University. The author has contributed to research in topics: Genome-wide association study & Mendelian Randomization Analysis. The author has an hindex of 7, co-authored 9 publications receiving 915 citations.
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Journal ArticleDOI
Association between C reactive protein and coronary heart disease: mendelian randomisation analysis based on individual participant data
G. Eiriksdottir,T. B. Harris,L. J. Launer,Vilmundur Gudnason,Aaron R. Folsom,Gavin Andrews,C. M. Ballantyne,Nilesh J. Samani,A. S. Hall,P. S. Braund,A. J. Balmforth,Peter H. Whincup,Richard W Morris,Debbie A Lawlor,Gordon D.O. Lowe,Nicholas J. Timpson,Shah Ebrahim,Yoav Ben-Shlomo,George Davey-Smith,Børge G. Nordestgaard,Anne Tybjærg-Hansen,Jeppe Zacho,Matthew A. Brown,Manjinder S. Sandhu,Sally L. Ricketts,Sofie Ashford,Leslie A. Lange,Alexander P. Reiner,Mary Cushman,Russel Tracy,C. Wu,J. Ge,Y. Zou,A. Sun,Joseph Hung,Brendan McQuillan,Peter L. Thompson,John Beilby,Nicole M. Warrington,Lyle J. Palmer,Christoph Wanner,Christiane Drechsler,Michael Hoffmann,F. G. R. Fowkes,Ioanna Tzoulaki,Meena Kumari,Michelle A. Miller,Michael Marmot,Charlotte Onland-Moret,Y. T. van der Schouw,J.M.A. Boer,Cisca Wijmenga,Kay-Tee Khaw,Ramachandran S. Vasan,Renate B. Schnabel,J. F. Yamamoto,E J Benjamin,Heribert Schunkert,Jeanette Erdmann,Inke R. König,Christian Hengstenberg,Benedetta D. Chiodini,MariaGrazia Franzosi,Silvia Pietri,Francesca Gori,Megan E. Rudock,Yongmei Liu,Kurt Lohman,Steve E. Humphries,Anders Hamsten,Paul Norman,Graeme J. Hankey,Konrad Jamrozik,Eric B. Rimm,J. K. Pai,Bruce M. Psaty,Susan R. Heckbert,J. C. Bis,Salim Yusuf,Sonia S. Anand,Engert Jc,C. Xie,Ryan L. Collins,Robert Clarke,David L.H. Bennett,Jaspal S. Kooner,John C. Chambers,Paul Elliott,W. März,Marcus E. Kleber,Bernhard O. Böhm,Winkelmann Br,Olle Melander,Göran Berglund,Wolfgang Koenig,Barbara Thorand,Jens Baumert,Annette Peters,JoAnn E. Manson,J.A. Cooper,P.J. Talmud,Per Ladenvall,Lovisa Johansson,J. H. Jansson,Göran Hallmans,Muredach P. Reilly,Liming Qu,Man Li,Daniel J. Rader,Hugh Watkins,Jemma C. Hopewell,Danish Saleheen,John Danesh,Philippe M. Frossard,Naveed Sattar,Michele Robertson,J. Shepherd,Ernst J. Schaefer,A. Hofman,J. C. M. Witteman,Isabella Kardys,Abbas Dehghan,U de Faire,Anna M. Bennet,Bruna Gigante,Karin Leander,Bas J M Peters,A.H. Maitland-van der Zee,A.H. De Boer,Olaf H. Klungel,Philip Greenland,J. Dai,Simin Liu,Eric J. Brunner,Mika Kivimäki,Denis St. J. O’Reilly,Ian Ford,Chris J. Packard +137 more
TL;DR: Human genetic data indicate that C reactive protein concentration itself is unlikely to be even a modest causal factor in coronary heart disease.
Journal ArticleDOI
Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.
Symen Ligthart,Ahmad Vaez,Urmo Võsa,Maria G. Stathopoulou,P. De Vries,Bram P. Prins,P. J. van der Most,Toshiko Tanaka,Elnaz Naderi,Lynda M. Rose,Ying Wu,Robert Karlsson,Maja Barbalić,Honghuang Lin,René Pool,Gu Zhu,Aurélien Macé,C Sidore,Stella Trompet,Massimo Mangino,Maria Sabater-Lleal,John P. Kemp,Ali Abbasi,Tim Kacprowski,Niek Verweij,Albert V. Smith,Tao Huang,Carola Marzi,Mary F. Feitosa,Kurt Lohman,Marcus E. Kleber,Yuri Milaneschi,Christine M. Mueller,M Huq,Efthymia Vlachopoulou,Lyytikäinen L-P.,Christopher Oldmeadow,Joris Deelen,Markus Perola,Jing Hua Zhao,Bjarke Feenstra,Marzyeh Amini,Jari Lahti,Katharina E. Schraut,Myriam Fornage,Bhoom Suktitipat,Chen W-M.,Xiaohui Li,Teresa Nutile,Giovanni Malerba,Jian'an Luan,Tom Bak,Nicholas J. Schork,Elisabeth Thiering,Anubha Mahajan,Riccardo E. Marioni,Evelin Mihailov,Joel Eriksson,Ayse Bilge Ozel,Weihua Zhang,Maria Nethander,Cheng Y-C.,Stella Aslibekyan,Wei Ang,Ilaria Gandin,Loic Yengo,Laura Portas,Charles Kooperberg,Edith Hofer,Kumar B. Rajan,Claudia Schurmann,W. den Hollander,Tarunveer S. Ahluwalia,Jing Zhao,Draisma Hhm.,Ian Ford,Nicholas J. Timpson,Alexander Teumer,Hongyan Huang,Simone Wahl,Yongmei Liu,Jinyan Huang,Uh H-W.,Frank Geller,Peter K. Joshi,Lisa R. Yanek,Elisabetta Trabetti,Benjamin Lehne,Diego Vozzi,M Verbanck,Ginevra Biino,Yasaman Saba,Ingrid Meulenbelt,Jeffery R. O'Connell,Markku Laakso,Franco Giulianini,Magnusson Pke.,Christie M. Ballantyne,J-J Hottenga,Grant W. Montgomery,Fernando Rivadineira,Rico Rueedi,Maristella Steri,Herzig K-H.,David J. Stott,Cristina Menni,Mattias Frånberg,B. St Pourcain,Stephan B. Felix,Tune H. Pers,Bakker Sjl.,Peter Kraft,Annette Peters,Dhananjay Vaidya,Graciela Delgado,Jan H. Smit,V Großmann,Juha Sinisalo,Ilkka Seppälä,Stephen R. Williams,Elizabeth G. Holliday,Matthijs Moed,Claudia Langenberg,Katri Räikkönen,Jun Ding,Harry Campbell,Michèle M. Sale,Chen Y-Di.,Chen Y-Di.,Alan James,Daniela Ruggiero,Nicole Soranzo,Catharina A. Hartman,Erin N. Smith,Gerald S. Berenson,Christian Fuchsberger,Dena G. Hernandez,Tiesler Cmt.,Vilmantas Giedraitis,D C Liewald,Krista Fischer,Dan Mellström,Anders Larsson,Yajuan Wang,William R. Scott,Mattias Lorentzon,John Beilby,Kathleen A. Ryan,Craig E. Pennell,Dragana Vuckovic,Beverley Balkau,Maria Pina Concas,Reinhold Schmidt,C. F. Mendes de Leon,C. F. Mendes de Leon,Erwin P. Bottinger,Margreet Kloppenburg,Lavinia Paternoster,Michael Boehnke,Arthur W. Musk,Gonneke Willemsen,David M. Evans,Madden Paf.,Mika Kähönen,Zoltán Kutalik,Magdalena Zoledziewska,Ville Karhunen,Stephen B. Kritchevsky,Naveed Sattar,Genevieve Lachance,Robert Clarke,T.B. Harris,Olli T. Raitakari,John Attia,D. van Heemst,Eero Kajantie,Rossella Sorice,Giovanni Gambaro,Robert A. Scott,Andrew A. Hicks,Luigi Ferrucci,M. Standl,Cecilia M. Lindgren,John M. Starr,Magnus Karlsson,Lars Lind,Jun Li,John C. Chambers,Trevor A. Mori,de Geus Ejcn.,A. C. Heath,Nicholas G. Martin,Juha Auvinen,Brendan M. Buckley,de Craen Ajm.,M. Waldenberger,Konstantin Strauch,Thomas Meitinger,R. J. Scott,Mark McEvoy,Marian Beekman,Cristina Bombieri,Paul M. Ridker,Karen L. Mohlke,Nancy L. Pedersen,A C Morrison,Dorret I. Boomsma,John Whitfield,David P. Strachan,Albert Hofman,Peter Vollenweider,Francesco Cucca,Jarvelin M-R.,Joop Jukema,Tim D. Spector,Anders Hamsten,Tanja Zeller,André G. Uitterlinden,Matthias Nauck,Vilmundur Gudnason,Lu Qi,H Grallert,Ingrid B. Borecki,Jerome I. Rotter,W. März,Philipp S. Wild,Lokki M-L.,Michael Boyle,Veikko Salomaa,Mads Melbye,Johan G. Eriksson,James F. Wilson,Penninx Bwjh.,Diane M. Becker,B. B. Worrall,Greg Gibson,Ronald M. Krauss,Marina Ciullo,Gianluigi Zaza,Nicholas J. Wareham,Albertine J. Oldehinkel,Lyle J. Palmer,Sarah S. Murray,Peter P. Pramstaller,Stefania Bandinelli,Joachim Heinrich,Erik Ingelsson,Ian J. Deary,Reedik Mägi,Liesbeth Vandenput,P. van der Harst,Karl C. Desch,Jaspal S. Kooner,Claes Ohlsson,Caroline Hayward,Terho Lehtimäki,Alan R. Shuldiner,Donna K. Arnett,Lawrie J. Beilin,Antonietta Robino,Philippe Froguel,Mario Pirastu,T. Jess,Wolfgang Koenig,Loos Rjf.,Denis A. Evans,Helena Schmidt,George Davey Smith,P E Slagboom,Gudny Eiriksdottir,Andrew P. Morris,Bruce M. Psaty,Russel Tracy,Ilja M. Nolte,Eric Boerwinkle,Sophie Visvikis-Siest,Alexander P. Reiner,Myron D. Gross,J. C. Bis,Lude Franke,Oscar H. Franco,E J Benjamin,Daniel I. Chasman,Josée Dupuis,Harold Snieder,Abbas Dehghan,Behrooz Z. Alizadeh +286 more
TL;DR: In this article, the authors performed two genome-wide association studies (GWASs), on HapMap and 1000 Genomes imputed data, of circulating amounts of CRP by using data from 88 studies comprising 204,402 European individuals.
Journal ArticleDOI
Genetic and non-genetic correlates of vitamins K and D
M Shea,E J Benjamin,Josée Dupuis,Joseph M. Massaro,Paul F. Jacques,Ralph B. D'Agostino,Jose M. Ordovas,Christopher J. O'Donnell,Bess Dawson-Hughes,Ramachandran S. Vasan,Sarah L. Booth +10 more
TL;DR: Variability in biomarkers of vitamin K status was attributed to nongenetic factors, whereas plasma 25(OH)D was found to be significantly heritable.
Application of non-HDL cholesterol for population-based cardiovascular risk stratification: results from the Multinational Cardiovascular Risk Consortium
Fabian J. Brunner,Christoph Waldeyer,Francisco Ojeda,Veikko Salomaa,Frank Kee,Susana Sans,Barbara Thorand,Simona Giampaoli,Paolo Brambilla,Hugh Tunstall-Pedoe,Marie Moitry,Licia Iacoviello,Giovanni Veronesi,Guido Grassi,Ellisiv B. Mathiesen,Stefan Söderberg,Allan Linneberg,Hermann Brenner,Philippe Amouyel,Jean Ferrières,Abdonas Tamosiunas,Yuriy P. Nikitin,Wojciech Drygas,Olle Melander,Karl-Heinz Joeckel,David M. Leistner,Jonathan E. Shaw,Demosthenes B. Panagiotakos,Leon A. Simons,Maryam Kavousi,Ramachandran S. Vasan,Robin P. F. Dullaart,S. Goya Wannamethee,Ulf Risérus,Steven Shea,James A. de Lemos,Torbjørn Omland,Kari Kuulasmaa,Ulf Landmesser,Stefan Blankenberg,Tanja Zeller,K.J. Lackner,Philipp S. Wild,Annette Peters,Christine Meisinger,Henry Voelzke,Marcus Doerr,Matthias Nauck,Ben Schoettker,Thiess Lorenz,Nataliya Makarova,Börge Schmidt,Jens Klotsche,Wolfgang Koenig,Jukka Kontto,Satu Männistö,T. Jaaskelainen,Teemu J. Niiranen,P. Jousilahti,A. Metspalu,Maris Alver,C. Donfrancesco,Stefano Signorini,Francesco Gianfagna,S. Costanzo,Mark Woodward,Annette J. Dobson,G.G. Giles,Allison M. Hodge,Dianna J. Magliano,Tom Wilsgaard,Magnus Lyngbakken,Kristian Hveem,Mats Eliasson,Gunnar Engström,Martin Ingelsson,Torben Jørgensen,Raphael Twerenbold,Jean Dallongeville,S. K. Malyutina,Andrzej Pajak,Martin Bobak,Peter H. Whincup,Christos Pitsavos,E J Benjamin,Stephan J. L. Bakker,Mohammad Kamran Ikram +86 more
TL;DR: Non-HDL cholesterol concentrations in blood are strongly associated with long-term risk of atherosclerotic cardiovascular disease and this tool provides a simple tool for individual long- term risk assessment and the potential benefit of early lipid-lowering intervention.
Journal ArticleDOI
Molecular Characterization of the NLRC4 Expression in Relation to Interleukin-18 Levels.
Tanja Zeller,Tina Haase,Christian P. Müller,Helene Riess,Denise Lau,Simon Zeller,Jasmin Krause,Jens Baumert,Ole Pless,Josée Dupuis,Philipp S. Wild,Medea S. Eleftheriadis,Melanie Waldenberger,Sonja Zeilinger,Andreas Ziegler,Annette Peters,Laurence Tiret,Carole Proust,Carola Marzi,Thomas Münzel,Konstantin Strauch,Holger Prokisch,Karl J. Lackner,Christian Herder,Barbara Thorand,E J Benjamin,Stefan Blankenberg,Wolfgang Koenig,Renate B. Schnabel +28 more
TL;DR: This study provides evidence for the functional causality of single nucleotide polymorphism rs385076 within the NLR family, caspase recruitment domain–containing 4 gene in relation to IL-18 activation.