A
Abbas Dehghan
Researcher at University of Washington
Publications - 7
Citations - 873
Abbas Dehghan is an academic researcher from University of Washington. The author has contributed to research in topics: Genome-wide association study & Chemokine. The author has an hindex of 3, co-authored 7 publications receiving 786 citations. Previous affiliations of Abbas Dehghan include Johns Hopkins University.
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Journal ArticleDOI
Association between C reactive protein and coronary heart disease: mendelian randomisation analysis based on individual participant data
G. Eiriksdottir,T. B. Harris,L. J. Launer,Vilmundur Gudnason,Aaron R. Folsom,Gavin Andrews,C. M. Ballantyne,Nilesh J. Samani,A. S. Hall,P. S. Braund,A. J. Balmforth,Peter H. Whincup,Richard W Morris,Debbie A Lawlor,Gordon D.O. Lowe,Nicholas J. Timpson,Shah Ebrahim,Yoav Ben-Shlomo,George Davey-Smith,Børge G. Nordestgaard,Anne Tybjærg-Hansen,Jeppe Zacho,Matthew A. Brown,Manjinder S. Sandhu,Sally L. Ricketts,Sofie Ashford,Leslie A. Lange,Alexander P. Reiner,Mary Cushman,Russel Tracy,C. Wu,J. Ge,Y. Zou,A. Sun,Joseph Hung,Brendan McQuillan,Peter L. Thompson,John Beilby,Nicole M. Warrington,Lyle J. Palmer,Christoph Wanner,Christiane Drechsler,Michael Hoffmann,F. G. R. Fowkes,Ioanna Tzoulaki,Meena Kumari,Michelle A. Miller,Michael Marmot,Charlotte Onland-Moret,Y. T. van der Schouw,J.M.A. Boer,Cisca Wijmenga,Kay-Tee Khaw,Ramachandran S. Vasan,Renate B. Schnabel,J. F. Yamamoto,E J Benjamin,Heribert Schunkert,Jeanette Erdmann,Inke R. König,Christian Hengstenberg,Benedetta D. Chiodini,MariaGrazia Franzosi,Silvia Pietri,Francesca Gori,Megan E. Rudock,Yongmei Liu,Kurt Lohman,Steve E. Humphries,Anders Hamsten,Paul Norman,Graeme J. Hankey,Konrad Jamrozik,Eric B. Rimm,J. K. Pai,Bruce M. Psaty,Susan R. Heckbert,J. C. Bis,Salim Yusuf,Sonia S. Anand,Engert Jc,C. Xie,Ryan L. Collins,Robert Clarke,David L.H. Bennett,Jaspal S. Kooner,John C. Chambers,Paul Elliott,W. März,Marcus E. Kleber,Bernhard O. Böhm,Winkelmann Br,Olle Melander,Göran Berglund,Wolfgang Koenig,Barbara Thorand,Jens Baumert,Annette Peters,JoAnn E. Manson,J.A. Cooper,P.J. Talmud,Per Ladenvall,Lovisa Johansson,J. H. Jansson,Göran Hallmans,Muredach P. Reilly,Liming Qu,Man Li,Daniel J. Rader,Hugh Watkins,Jemma C. Hopewell,Danish Saleheen,John Danesh,Philippe M. Frossard,Naveed Sattar,Michele Robertson,J. Shepherd,Ernst J. Schaefer,A. Hofman,J. C. M. Witteman,Isabella Kardys,Abbas Dehghan,U de Faire,Anna M. Bennet,Bruna Gigante,Karin Leander,Bas J M Peters,A.H. Maitland-van der Zee,A.H. De Boer,Olaf H. Klungel,Philip Greenland,J. Dai,Simin Liu,Eric J. Brunner,Mika Kivimäki,Denis St. J. O’Reilly,Ian Ford,Chris J. Packard +137 more
TL;DR: Human genetic data indicate that C reactive protein concentration itself is unlikely to be even a modest causal factor in coronary heart disease.
Journal ArticleDOI
Uromodulin Levels Associate with a Common UMOD Variant and Risk for Incident CKD
Anna Köttgen,Shih-Jen Hwang,Martin G. Larson,Jennifer E. Van Eyk,Qin Fu,Emelia J. Benjamin,Emelia J. Benjamin,Abbas Dehghan,Nicole L. Glazer,W. H. Linda Kao,Tamara B. Harris,Vilmundur Gudnason,Michael G. Shlipak,Qiong Yang,Josef Coresh,Daniel Levy,Caroline S. Fox,Caroline S. Fox +17 more
TL;DR: Elevated uromodulin concentrations precede the onset of CKD and associate with a common polymorphism in the UMOD region, according to a case-control study of incident CKD within the Framingham Heart Study.
Journal ArticleDOI
Common Genetic Variants Associate with Serum Phosphorus Concentration
Bryan Kestenbaum,Nicole L. Glazer,Anna Köttgen,Janine F. Felix,Shih-Jen Hwang,Yongmei Liu,Kurt Lohman,Stephen B. Kritchevsky,Dorothy B. Hausman,Ann Kristin Petersen,Christian Gieger,Janina S. Ried,Thomas Meitinger,Tim Matthias Strom,H.-Erich Wichmann,Harry Campbell,Caroline Hayward,Igor Rudan,Ian H. de Boer,Bruce M. Psaty,Kenneth Rice,Yii-Der Ida Chen,Man Li,D.E. Arking,Eric Boerwinkle,Josef Coresh,Qiong Yang,Daniel Levy,Frank J.A. van Rooij,Abbas Dehghan,Fernando Rivadeneira,AndréG Uitterlinden,Albert Hofman,Cornelia M. van Duijn,Michael G. Shlipak,W. H. Linda Kao,Jacqueline C.M. Witteman,David S. Siscovick,Caroline S. Fox +38 more
TL;DR: Common genetic variants associate with serum phosphorus in the general population and three loci were near genes encoding the kidney-specific type IIa sodium phosphate co-transporter, the calcium-sensing receptor, and fibroblast growth factor 23 (FGF23), proteins that contribute to phosphorus metabolism.
Association of Novel Genetic Loci with Circulating Fibrinogen Levels: A Genome-Wide Association Study in Six Population- Based Cohorts:
Abbas Dehghan,Qiong Yang,Annette Peters,Saonli Basu,Joshua C. Bis,Alicja R Rudnicka,M. Kavousi,Jens Baumert,Gordon D.O. Lowe,Barbara McKnight,Weihong Tang,Martin G. Larson,Wendy McArdle,Thomas Lumley,James S. Pankow,Albert Hofman,Joseph M. Massaro,Fernando Rivadeneira,Melanie Kolz,Kent D. Taylor,Cornelia M. van Duijn,Thomas Illig,Yurii S. Aulchenko,Kelly A. Volcik,Andrew D. Johnson,André G. Uitterlinden,Geoffrey H. Tofler,Christian Gieger,Bruce M. Psaty,Eric Boerwinkle,Wolfgang Koenig,Jacqueline C. M. Witteman,David P. Strachan,Nicholas L. Smith,Aaron R. Folsom +34 more
Genomic variation associated with mortality among adults of European and African ancestry with heart failure: the CHARGE Consortium Running title: Morrison et al; Genomic variation and mortality in adults with HF
Alanna C. Morrison,Janine F. Felix,L. Adrienne Cupples,Laura R. Loehr,Abbas Dehghan,Joshua C. Bis,Wayne D. Rosamond,Yurii S. Aulchenko,Ying A. Wang,Talin Haritunians,Aaron R. Folsom,Fernando Rivadeneira,Thomas Lumley,David J. Couper,Kenneth M. Rice,Patricia P. Chang,Daniel Levy,Jerome I. Rotter,Ervin R. Fox,Thomas J. Wang,Bruce M. Psaty,James T. Willerson,Cornelia M. van Duijn,Eric Boerwinkle,Jacqueline C. M. Witteman,Ramachandran S. Vasan,Nicholas L. Smith,Sci Ctr,Erasmus Mc +28 more
TL;DR: Alanna C. Morrison PhD*, Janine F. Felix MD PhD*, L. R. Glazer PhD*, Laura R. Loehr MD PhD, Abbas Dehghan MD DSc, Serkalem Demissie PhD, Joshua C. Wang PhD, Talin Haritunians PhD, Aaron R. Folsom MD, Fernando RivadeneiraMD PhD, Emelia J.Uitterlinden PhD, Thomas J.Stricker MD PhD.