F
Farid Radmanesh
Researcher at Harvard University
Publications - 36
Citations - 1838
Farid Radmanesh is an academic researcher from Harvard University. The author has contributed to research in topics: Genome-wide association study & Population. The author has an hindex of 20, co-authored 34 publications receiving 1446 citations. Previous affiliations of Farid Radmanesh include Tehran University of Medical Sciences & University of Tehran.
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Journal ArticleDOI
Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation
Ingrid E. Christophersen,Ingrid E. Christophersen,Ingrid E. Christophersen,Michiel Rienstra,Carolina Roselli,Carolina Roselli,Xiaoyan Yin,Xiaoyan Yin,Bastiaan Geelhoed,John Barnard,Honghuang Lin,Honghuang Lin,Dan E. Arking,Albert V. Smith,Christine M. Albert,Mark Chaffin,Nathan R. Tucker,Nathan R. Tucker,Molong Li,Derek Klarin,Nathan A. Bihlmeyer,Siew-Kee Low,Peter Weeke,Peter Weeke,Martina Müller-Nurasyid,J. Gustav Smith,J. Gustav Smith,Jennifer A. Brody,Maartje N. Niemeijer,Marcus Dörr,Stella Trompet,Jennifer E. Huffman,Stefan Gustafsson,Claudia Schurmann,Marcus E. Kleber,Leo-Pekka Lyytikäinen,Ilkka Seppälä,Rainer Malik,Andrea R. V. R. Horimoto,Marco V Perez,Juha Sinisalo,Stefanie Aeschbacher,Sébastien Thériault,Sébastien Thériault,Jie Yao,Farid Radmanesh,Farid Radmanesh,Stefan Weiss,Alexander Teumer,Seung Hoan Choi,Lu-Chen Weng,Lu-Chen Weng,Sebastian Clauss,Sebastian Clauss,Rajat Deo,Daniel J. Rader,Svati H. Shah,Albert Y. Sun,Jemma C. Hopewell,Stéphanie Debette,Ganesh Chauhan,Ganesh Chauhan,Qiong Yang,Bradford B. Worrall,Guillaume Paré,Guillaume Paré,Yoichiro Kamatani,Yanick Hagemeijer,Niek Verweij,Joylene E. Siland,Michiaki Kubo,Jonathan D. Smith,David R. Van Wagoner,Joshua C. Bis,Siegfried Perz,Bruce M. Psaty,Bruce M. Psaty,Bruce M. Psaty,Paul M. Ridker,Jared W. Magnani,Jared W. Magnani,Tamara B. Harris,Lenore J. Launer,M. Benjamin Shoemaker,Sandosh Padmanabhan,Jeffrey Haessler,Traci M. Bartz,Melanie Waldenberger,Peter Lichtner,Marina Arendt,José Eduardo Krieger,Mika Kähönen,Lorenz Risch,Alfredo José Mansur,Annette Peters,Blair H. Smith,Lars Lind,Stuart A. Scott,Yingchang Lu,Erwin B. Bottinger,Jussi Hernesniemi,Cecilia M. Lindgren,Jorge A. Wong,Jie Huang,Markku Eskola,Andrew P. Morris,Andrew P. Morris,Ian Ford,Alexander P. Reiner,Alexander P. Reiner,Graciela Delgado,Lin Y. Chen,Yii-Der Ida Chen,Roopinder K. Sandhu,Man Li,Man Li,Eric Boerwinkle,Lewin Eisele,Lars Lannfelt,Natalia S. Rost,Natalia S. Rost,Christopher D. Anderson,Christopher D. Anderson,Kent D. Taylor,Archie Campbell,Patrik K. E. Magnusson,David J. Porteous,Lynne J. Hocking,Efthymia Vlachopoulou,Nancy L. Pedersen,Kjell Nikus,Marju Orho-Melander,Anders Hamsten,Jan Heeringa,Joshua C. Denny,Jennifer Kriebel,Dawood Darbar,Christopher Newton-Cheh,Christopher Newton-Cheh,Christian M. Shaffer,Peter W. Macfarlane,Stefanie Heilmann-Heimbach,Peter Almgren,Paul L. Huang,Nona Sotoodehnia,Elsayed Z. Soliman,André G. Uitterlinden,Albert Hofman,Oscar H. Franco,Uwe Völker,Karl-Heinz Jöckel,Moritz F. Sinner,Henry J. Lin,Xiuqing Guo,Martin Dichgans,Martin Dichgans,Erik Ingelsson,Erik Ingelsson,Charles Kooperberg,Olle Melander,Ruth J. F. Loos,Jari Laurikka,David Conen,David Conen,Jonathan Rosand,Jonathan Rosand,Pim van der Harst,Marja-Liisa Lokki,Sekar Kathiresan,Alexandre C. Pereira,J. Wouter Jukema,Caroline Hayward,Jerome I. Rotter,Winfried März,Winfried März,Terho Lehtimäki,Bruno H. Stricker,Mina K. Chung,Stephan B. Felix,Vilmundur Gudnason,Alvaro Alonso,Dan M. Roden,Stefan Kääb,Daniel I. Chasman,Daniel I. Chasman,Susan R. Heckbert,Susan R. Heckbert,Emelia J. Benjamin,Emelia J. Benjamin,Toshihiro Tanaka,Kathryn L. Lunetta,Kathryn L. Lunetta,Steven A. Lubitz,Steven A. Lubitz,Patrick T. Ellinor,Patrick T. Ellinor +195 more
TL;DR: 12 new genetic loci that exceeded genome-wide significance, implicating genes involved in cardiac electrical and structural remodeling are identified, providing insights into the molecular basis of atrial fibrillation and may facilitate the identification of new potential targets for drug discovery.
Journal ArticleDOI
Meta-analysis of Genome-wide Association Studies Identifies 1q22 as a Susceptibility Locus for Intracerebral Hemorrhage
Daniel Woo,Guido J. Falcone,Guido J. Falcone,William J. Devan,William J. Devan,W. Mark Brown,Alessandro Biffi,Alessandro Biffi,Timothy D. Howard,Christopher D. Anderson,Christopher D. Anderson,H. Bart Brouwers,H. Bart Brouwers,Valerie Valant,Valerie Valant,Thomas W.K. Battey,Thomas W.K. Battey,Farid Radmanesh,Farid Radmanesh,Miriam R. Raffeld,Miriam R. Raffeld,Sylvia Baedorf-Kassis,Sylvia Baedorf-Kassis,Ranjan Deka,Jessica G. Woo,Lisa J. Martin,Mary Haverbusch,Charles J Moomaw,Guangyun Sun,Joseph P. Broderick,Matthew L. Flaherty,Sharyl Martini,Dawn Kleindorfer,Brett M. Kissela,Mary E. Comeau,Jeremiasz M. Jagiella,Helena Schmidt,Paul Freudenberger,Alexander Pichler,Christian Enzinger,Björn M. Hansen,Bo Norrving,Jordi Jimenez-Conde,Jordi Jimenez-Conde,Eva Giralt-Steinhauer,Eva Giralt-Steinhauer,Roberto Elosua,Roberto Elosua,Elisa Cuadrado-Godia,Elisa Cuadrado-Godia,Carolina Soriano,Carolina Soriano,Jaume Roquer,Jaume Roquer,Peter Kraft,Alison M. Ayres,Kristin Schwab,Jacob L. McCauley,Joanna Pera,Andrzej Urbanik,Natalia S. Rost,Natalia S. Rost,Joshua N. Goldstein,Anand Viswanathan,Eva Maria Stögerer,David L. Tirschwell,Magdy Selim,Devin L. Brown,Scott Silliman,Bradford B. Worrall,James F. Meschia,Chelsea S. Kidwell,Joan Montaner,Israel Fernandez-Cadenas,Pilar Delgado,Rainer Malik,Martin Dichgans,Steven M. Greenberg,Peter M. Rothwell,Arne Lindgren,Agnieszka Slowik,Reinhold Schmidt,Carl D. Langefeld,Jonathan Rosand,Jonathan Rosand +84 more
TL;DR: A genome-wide association study of this condition that meta-analyzed data from six studies that enrolled individuals of European ancestry demonstrated biological heterogeneity across ICH subtypes and highlighted the importance of ascertaining ICH cases accordingly.
Journal ArticleDOI
Identification of additional risk loci for stroke and small vessel disease: a meta-analysis of genome-wide association studies
Ganesh Chauhan,Corey R. Arnold,Audrey Y. Chu,Myriam Fornage,Azadeh Reyahi,Joshua C. Bis,Aki S. Havulinna,Muralidharan Sargurupremraj,Albert V. Smith,Hieab H.H. Adams,Seung Hoan Choi,Sara L. Pulit,Stella Trompet,Melissa E. Garcia,Ani Manichaikul,Alexander Teumer,Stefan Gustafsson,Traci M. Bartz,Céline Bellenguez,Jean-Sébastien Vidal,Xueqiu Jian,Olafur Kjartansson,Kerri L. Wiggins,Claudia L. Satizabal,Flora Xue,Samuli Ripatti,Yongmei Liu,Joris Deelen,Marcel den Hoed,Steve Bevan,Jemma C. Hopewell,Rainer Malik,Susan R. Heckbert,Kenneth Rice,Nicholas L. Smith,Christopher R Levi,Pankaj Sharma,Cathie Sudlow,Ali Moussavi Nik,John W. Cole,Reinhold E. Schmidt,James F. Meschia,Vincent Thijs,Arne Lindgren,Olle Melander,Raji P. Grewal,Ralph L. Sacco,Tatjana Rundek,Peter M. Rothwell,Donna K. Arnett,Christina Jern,Julie A. Johnson,Oscar R. Benavente,Sylvia Wassertheil-Smoller,Jin-Moo Lee,Quenna Wong,Hugo J. Aparicio,Stefan T. Engelter,Manja Kloss,Didier Leys,Alessandro Pezzini,Julie E. Buring,Paul M. Ridker,Claudine Berr,Jean-François Dartigues,Anders Hamsten,Patrik K. E. Magnusson,Matthew Traylor,Nancy L. Pedersen,Lars Lannfelt,Lars Lindgren,Cecilia M. Lindgren,Andrew P. Morris,Jordi Jimenez-Conde,Joan Montaner,Farid Radmanesh,Agnieszka Slowik,Daniel Woo,Albert Hofman,Peter J. Koudstaal,Marileen L.P. Portegies,André G. Uitterlinden,Anton J. M. de Craen,Ian Ford,J. Wouter Jukema,David J. Stott,Norrina B. Allen,Michèle M. Sale,Andrew D. Johnson,David A. Bennett,Philip L. De Jager,Charles C. White,Hans J. Grabe,Marcello Ricardo Paulista Markus,Ulf Schminke,Giorgio B. Boncoraglio,Robert Clarke,Yoichiro Kamatani,Jean Dallongeville,Oscar L. Lopez,Jerome I. Rotter,Mike A. Nalls,Rebecca F. Gottesman,Michael Griswold,David S. Knopman,B. Gwen Windham,Alexa S. Beiser,Hugh S. Markus,Erkki Vartiainen,Curtis R. French,Martin Dichgans,Tomi Pastinen,Mark Lathrop,Vilmundur Gudnason,Tobias Kurth,Bruce M. Psaty,Tamara B. Harris,Stephen S. Rich,Anita L. DeStefano,Carsten Oliver Schmidt,Bradford B. Worrall,Jonathan Rosand,Veikko Salomaa,Thomas H. Mosley,Erik Ingelsson,Cornelia M. van Duijn,Christophe Tzourio,Kathryn M. Rexrode,Ordan J. Lehmann,Lenore J. Launer,M. Arfan Ikram,Peter Carlsson,Daniel I. Chasman,Sarah J. Childs,William T. Longstreth,Sudha Seshadri,Stéphanie Debette +136 more
TL;DR: Empirical and experimental data suggest that FOXF2 mediates this association, potentially via differentiation defects of cerebral vascular mural cells, and further expression studies in appropriate human tissues are needed to fully understand the underlying mechanisms.
Journal ArticleDOI
Common variation in COL4A1/COL4A2 is associated with sporadic cerebral small vessel disease.
Kristiina Rannikmäe,Gail Davies,Pippa A. Thomson,Steve Bevan,William J. Devan,Guido J. Falcone,Matthew Traylor,Christopher D. Anderson,Thomas W.K. Battey,Farid Radmanesh,Ranjan Deka,Jessica G. Woo,Lisa J. Martin,Jordi Jimenez-Conde,Magdy Selim,Devin L. Brown,Scott Silliman,Chelsea S. Kidwell,Joan Montaner,Carl D. Langefeld,Agnieszka Slowik,Björn M. Hansen,Arne Lindgren,James F. Meschia,Myriam Fornage,Joshua C. Bis,Stéphanie Debette,Mohammad Arfan Ikram,Will Longstreth,Reinhold Schmidt,Cathy R. Zhang,Qiong Yang,Pankaj Sharma,Steven J. Kittner,Braxton D. Mitchell,Elizabeth G. Holliday,Christopher R Levi,John Attia,Peter M. Rothwell,D Poole,Giorgio B. Boncoraglio,Bruce M. Psaty,Rainer Malik,Natalia S. Rost,Bradford B. Worrall,Martin Dichgans,Tom Van Agtmael,Daniel Woo,Hugh S. Markus,Sudha Seshadri,Jonathan Rosand,Cathie Sudlow +51 more
TL;DR: The results indicate an association between common variation in the COL4A2 gene and symptomatic small vessel disease, particularly deep intracerebral hemorrhage, and merit replication studies, including in ethnic groups of non-European ancestry.
Journal ArticleDOI
Genome-wide association study (gwas) and genome-wide by environment interaction study (gweis) of depressive symptoms in african american and hispanic/latina women.
Erin C. Dunn,Erin C. Dunn,Anna Wiste,Farid Radmanesh,Farid Radmanesh,Lynn M. Almli,Stephanie M. Gogarten,Tamar Sofer,Jessica D. Faul,Sharon L.R. Kardia,Jennifer A. Smith,David R. Weir,Wei Zhao,Thomas W. Soare,Thomas W. Soare,Saira Saeed Mirza,Karin Hek,Henning Tiemeier,Joseph S. Goveas,Gloria E. Sarto,Beverly M. Snively,Marilyn C. Cornelis,Karestan C. Koenen,Peter Kraft,Shaun Purcell,Kerry J. Ressler,Jonathan Rosand,Jonathan Rosand,Sylvia Wassertheil-Smoller,Jordan W. Smoller,Jordan W. Smoller +30 more
TL;DR: A GWAS and genome‐wide by environment interaction study of depressive symptoms and considers gene–environment interaction (GxE) might improve efficiency for gene discovery.