P
Peter Wipf
Researcher at University of Pittsburgh
Publications - 795
Citations - 27717
Peter Wipf is an academic researcher from University of Pittsburgh. The author has contributed to research in topics: Total synthesis & Transmetalation. The author has an hindex of 83, co-authored 767 publications receiving 25316 citations. Previous affiliations of Peter Wipf include University of California, Los Angeles & University of Vermont.
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Formulations and carrier systems including compound interactive domains
TL;DR: In this article, a method of creating a formulation for a compound includes determining a compound interactive agent comprising at least one group that interacts with the compound, creating a carrier agent by conjugating at least 1 compound interactive domain with at least 2 hydrophilic domains, and combining the compound and the carrier agent to create the formulation.
Journal ArticleDOI
Total Synthesis and Revision of Stereochemistry of the Marine Metabolite Trunkamide A.
Peter Wipf,Yoshikazu Uto +1 more
TL;DR: In this article, the first synthesis of actual trunkamide A in a total synthesis that serves as an unambiguous structural and stereochemical proof was reported, with a Lewis acid assisted aziridine opening used for the preparation of the reverse-prenylated serine and threonine side chains as well as an efficient oxazoline-thiazoline interconversion on the macrocyclic skeleton.
Journal ArticleDOI
Total Synthesis of (-)-Disorazole C1.
Peter Wipf,Thomas H. Graham +1 more
TL;DR: In this paper, a highly convergent and stereoselective total synthesis of disorazole C1 was presented. But the synthesis strategy was not considered in this paper.
Journal ArticleDOI
How mono- and diphosphine ligands alter regioselectivity of the Rh-catalyzed annulative cleavage of bicyclo[1.1.0]butanes
TL;DR: In this paper , quantum mechanical DFT calculations pinpoint a reversal of regio- and diastereoselectivity, suggesting a concerted (double) C−C bond cleavage and rhodium carbenoid formation, driven by strain-release.