P
Peter Wipf
Researcher at University of Pittsburgh
Publications - 795
Citations - 27717
Peter Wipf is an academic researcher from University of Pittsburgh. The author has contributed to research in topics: Total synthesis & Transmetalation. The author has an hindex of 83, co-authored 767 publications receiving 25316 citations. Previous affiliations of Peter Wipf include University of California, Los Angeles & University of Vermont.
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Stereochemical control in the ester enolate Claisen rearrangement. 2. Chairlike vs boatlike transition-state selection
TL;DR: In this paper, the preference for chair-and boat-like transition state geometries in the ester enolate Claisen rearrangement of straight chain, carbocyclic, and heter-cyclic propanoates was investigated.
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Dual specificity protein phosphatases: therapeutic targets for cancer and Alzheimer's disease.
TL;DR: The dual-specificity phosphatases, which dephosphorylate serine, threonine, and tyrosine residues in the same protein substrate, have important roles in multiple signaling pathways and appear to be deregulated in cancer and Alzheimer's disease.
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A General Strategy for Five-Membered Heterocycle Synthesis by Cycloelimination of Alkynyl Ketones, Amides, and Thioamides
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Protein kinase D as a potential new target for cancer therapy
Courtney R. LaValle,Kara M. George,Elizabeth R. Sharlow,John S. Lazo,Peter Wipf,Q. Jane Wang +5 more
TL;DR: This review focuses on the potential of PKD as a chemotherapeutic target in cancer treatment and highlights important recent advances in the development ofPKD inhibitors.