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Samuel J. Aronson
Researcher at Partners HealthCare
Publications - 37
Citations - 2733
Samuel J. Aronson is an academic researcher from Partners HealthCare. The author has contributed to research in topics: Clinical decision support system & Health informatics. The author has an hindex of 16, co-authored 32 publications receiving 2285 citations. Previous affiliations of Samuel J. Aronson include National Institutes of Health & Brigham and Women's Hospital.
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Journal ArticleDOI
Using Multiplexed Assays of Oncogenic Drivers in Lung Cancers to Select Targeted Drugs
Mark G. Kris,Bruce E. Johnson,Lynne D. Berry,David J. Kwiatkowski,A. John Iafrate,Ignacio I. Wistuba,Marileila Varella-Garcia,Wilbur A. Franklin,Samuel J. Aronson,Pei Fang Su,Yu Shyr,D. Ross Camidge,Lecia V. Sequist,Bonnie S. Glisson,Fadlo R. Khuri,Edward B. Garon,William Pao,Charles M. Rudin,Joan H. Schiller,Eric B. Haura,Mark A. Socinski,Keisuke Shirai,Heidi Chen,Giuseppe Giaccone,Giuseppe Giaccone,Marc Ladanyi,Kelly Kugler,John D. Minna,Paul A. Bunn +28 more
TL;DR: The Lung Cancer Mutation Consortium was formed to perform multiplexed assays testing adenocarcinomas of the lung for drivers in 10 genes to enable clinicians to select targeted treatments and enroll patients into clinical trials.
Journal ArticleDOI
Building the foundation for genomics in precision medicine
Samuel J. Aronson,Heidi L. Rehm +1 more
TL;DR: To accelerate the adoption of precision medicine, fundamental changes are needed in the infrastructure and mechanisms for data collection, storage and sharing to create a continuously learning health-care system with seamless cycling between clinical care and research.
Journal ArticleDOI
Clinical Sequencing Exploratory Research Consortium: Accelerating Evidence-Based Practice of Genomic Medicine
Robert C. Green,Robert C. Green,Katrina A.B. Goddard,Gail P. Jarvik,Laura M. Amendola,Paul S. Appelbaum,Jonathan S. Berg,Barbara A. Bernhardt,Leslie G. Biesecker,Sawona Biswas,Carrie L. Blout,Kevin M. Bowling,Wylie Burke,Charlisse F. Caga-anan,Arul M. Chinnaiyan,Arul M. Chinnaiyan,Wendy K. Chung,Ellen Wright Clayton,Gregory M. Cooper,Kelly M. East,James P. Evans,Stephanie M. Fullerton,Levi A. Garraway,Levi A. Garraway,Jeremy R. Garrett,Jeremy R. Garrett,Stacy W. Gray,Gail E. Henderson,Lucia A. Hindorff,Ingrid A. Holm,Michelle Huckaby Lewis,Carolyn M. Hutter,Pasi A. Jänne,Steven Joffe,David J. Kaufman,Bartha Maria Knoppers,Barbara A. Koenig,Ian D. Krantz,Teri A. Manolio,Laurence B. McCullough,Jean E. McEwen,Amy L. McGuire,Donna M. Muzny,Richard M. Myers,Deborah A. Nickerson,Jeffrey Ou,Donald W. Parsons,Gloria M. Petersen,Sharon E. Plon,Heidi L. Rehm,J. Scott Roberts,Dan R. Robinson,Joseph Salama,Sarah Scollon,Richard R. Sharp,Brian H. Shirts,Nancy B. Spinner,Holly K. Tabor,Peter Tarczy-Hornoch,David L. Veenstra,Nikhil Wagle,Nikhil Wagle,Karen E. Weck,Benjamin S. Wilfond,Kirk C. Wilhelmsen,Susan M. Wolf,Julia Wynn,Joon Ho Yu,Michelle D. Amaral,Samuel J. Aronson,Shubhangi Arora,Danielle R. Azzariti,Greg Barsh,E. M. Bebin,Barbara B. Biesecker,Brian L. Brown,Amber A. Burt,Peter H. Byers,Muge G. Calikoglu,Sara J. Carlson,Nizar Chahin,Kurt D. Christensen,Allison L. Cirino,Laura K. Conlin,Greg M. Cooper,David R. Crosslin,James V. Davis,Kelly Davis,Matthew A. Deardorff,Batsal Devkota,Raymond De Vries,Pamela M. Diamond,Michael O. Dorschner,Noreen P. Dugan,Dmitry Dukhovny,Matthew C. Dulik,Kelly M. East,Edgar A. Rivera-Munoz,Barbara J. Evans,Jessica Everett,Nicole Exe,Zheng Fan,Lindsay Z. Feuerman,Kelly K. Filipski,Candice R. Finnila,Kristen P Fishler,Bob Ghrundmeier,Karen Giles,Marian J. Gilmore,Zahra S. Girnary,Steven Gonsalves,Adam S. Gordon,Michele C. Gornick,William M. Grady,David E. Gray,Robert S. Greenwood,Amanda M. Gutierrez,Paul K. J. Han,Ragan Hart,Patrick J. Heagerty,Naomi Hensman,Susan M. Hiatt,Patricia Himes,Fuki M. Hisama,Carolyn Y. Ho,Lily B. Hoffman-Andrews,Celine Hong,Martha Horike-Pyne,Sara Chandros Hull,Seema M. Jamal,Brian C. Jensen,Jennifer J. Johnston,Dean Karavite,Tia L. Kauffman,Dave Kaufman,Whitley V. Kelley,Jerry H. Kim,Christine Kirby,William M. P. Klein,Sek Won Kong,Joel B. Krier,Neil E. Lamb,Michele P. Lambert,Lan Q. Le,Matthew S. Lebo,Alexander Lee,Kaitlyn B. Lee,Niall J. Lennon,Michael C. Leo,Kathleen A. Leppig,Katie L. Lewis,Neal I. Lindeman,Nicole Lockhart,Bob Lonigro,Edward J. Lose,Philip J. Lupo,Laura Lyman Rodriguez,Frances L. Lynch,Kalotina Machini,Calum A. MacRae,Daniel S. Marchuk,Josue N. Martinez,Aaron J. Masino,Heather M. McLaughlin,Carmit K. McMullen,Piotr A. Mieczkowski,Jeffrey W. Miller,Victoria A. Miller,Rajen Mody,Sean D. Mooney,Elizabeth G. Moore,Elissa Morris,Michael F. Murray,David Ng,Nelly Oliver,Will Parsons,Donald L. Patrick,Jeffrey W. Pennington,Denise L. Perry,Katie Porter,Bradford C. Powell,Sumit Punj,Carmen Radecki Breitkopf,Robin A. Raesz-Martinez,Wendy H. Raskind,Dean A. Reigar,Jacob A. Reiss,Carla A. Rich,Carolyn Sue Richards,Christine Rini,Scott Roberts,Peggy D. Robertson,Jill O. Robinson,Marguerite E. Robinson,Myra I. Roche,Edward J. Romasko,Elisabeth A. Rosenthal,Maria I. Scarano,Jennifer L. Schneider,Christine E. Seidman,Bryce A. Seifert,Brian H. Shirts,Lynette M. Sholl,Javed Siddiqui,Elian Silverman,Shirley Simmons,Janae V. Simons,Debra Skinner,Elena M. Stoffel,Natasha T. Strande,Shamil R. Sunyaev,Virginia P. Sybert,Jennifer M. Taber,Deanne Taylor,Christine R. Tilley,Ashley N. Tomlinson,Susan Brown Trinidad,Ellen A. Tsai,Eliezer M. Van Allen,Jason L. Vassy,Pankaj Vats,Victoria L. Vetter,Raymond De Vries,Sarah A. Walser,Rebecca C. Walsh,Allison Werner-Lin,Jana Whittle,Kirk C. Wilhelmsen,Yaping Yang,Carol Young,Brian J. Zikmund-Fisher +230 more
TL;DR: The CSER consortium is exploring analytic and clinical validity and utility, as well as the ethical, legal, and social implications of sequencing via multidisciplinary approaches; it has recruited 5,577 participants across a spectrum of symptomatic and healthy children and adults by utilizing both germline and cancer sequencing.
Journal ArticleDOI
Communicating new knowledge on previously reported genetic variants
Samuel J. Aronson,Eugene Clark,Matthew Varugheese,Samantha Baxter,Lawrence J. Babb,Heidi L. Rehm,Heidi L. Rehm +6 more
TL;DR: An infrastructure enabling clinicians to receive knowledge updates when a laboratory changes the classification of a variant is deployed, and statistics regarding the frequency of both variant classification changes and the effects of these classification changes on patients are gathered.
Journal ArticleDOI
Research Directions in the Clinical Implementation of Pharmacogenomics: An Overview of US Programs and Projects.
Simona Volpi,Carol J. Bult,Rex L. Chisholm,Patricia A. Deverka,Geoffrey S. Ginsburg,Howard J. Jacob,Melpomeni Kasapi,Howard L. McLeod,Dan M. Roden,Marc S. Williams,Eric D. Green,Laura Lyman Rodriguez,Samuel J. Aronson,Larisa H. Cavallari,Joshua C. Denny,Lynn G. Dressler,Julie A. Johnson,Teri E. Klein,J. Steven Leeder,Micheline Piquette-Miller,Minoli A. Perera,Laura J. Rasmussen-Torvik,Heidi L. Rehm,Marylyn D. Ritchie,Todd C. Skaar,Nikhil Wagle,Richard M. Weinshilboum,Kristin Weitzel,Robert Wildin,John Wilson,Teri A. Manolio,Mary V. Relling +31 more
TL;DR: The US landscape of research programs in PGx implementation is surveyed, current advances and clinical applications of PGx are reviewed, the obstacles that have hindered implementation are summarized, and critical knowledge gaps are identified and possible studies needed to help to address them.