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Sarah E. Bohndiek
Researcher at University of Cambridge
Publications - 176
Citations - 5551
Sarah E. Bohndiek is an academic researcher from University of Cambridge. The author has contributed to research in topics: Medicine & Hyperspectral imaging. The author has an hindex of 30, co-authored 141 publications receiving 4254 citations. Previous affiliations of Sarah E. Bohndiek include Engineering and Physical Sciences Research Council & University College London.
Papers
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Journal ArticleDOI
Contrast agents for molecular photoacoustic imaging
TL;DR: The physical, chemical and biochemical characteristics of the existing photoacoustic contrast agents are critically reviewed, highlighting key applications and present challenges for molecular PAI.
Journal ArticleDOI
Imaging biomarker roadmap for cancer studies.
James P B O'Connor,Eric O. Aboagye,Judith E. Adams,Hugo J.W.L. Aerts,Hugo J.W.L. Aerts,Sally F. Barrington,Ambros J. Beer,Ronald Boellaard,Sarah E. Bohndiek,J. Michael Brady,Gina Brown,David L. Buckley,Thomas L. Chenevert,Laurence P. Clarke,Sandra Collette,Gary Cook,Nandita M. deSouza,John Dickson,Caroline Dive,Jeffrey L. Evelhoch,Corinne Faivre-Finn,Ferdia A. Gallagher,Fiona J. Gilbert,Robert J. Gillies,Vicky Goh,John R. Griffiths,Ashley M. Groves,Steve Halligan,Adrian L. Harris,David J. Hawkes,Otto S. Hoekstra,Erich P. Huang,Brian Hutton,Edward F. Jackson,Gordon C Jayson,Andrew J. I. Jones,Dow-Mu Koh,Denis Lacombe,Philippe Lambin,Nathalie Lassau,Martin O. Leach,Ting-Yim Lee,Edward Leen,Jason S. Lewis,Yan Liu,Mark F. Lythgoe,Prakash Manoharan,Ross J. Maxwell,Kenneth A. Miles,Bruno Morgan,Steve Morris,Tony Ng,Anwar R. Padhani,Geoff J M Parker,Mike Partridge,Arvind P. Pathak,Arvind P. Pathak,Andrew C. Peet,Shonit Punwani,Andrew R. Reynolds,Simon P. Robinson,Lalitha K. Shankar,Ricky A. Sharma,Dmitry Soloviev,Sigrid Stroobants,Daniel C. Sullivan,Stuart A. Taylor,Paul S. Tofts,Gillian M. Tozer,Marcel van Herk,Simon Walker-Samuel,James Wason,Kaye J. Williams,Paul Workman,Thomas E. Yankeelov,Kevin M. Brindle,Lisa M. McShane,Alan Jackson,John C. Waterton +78 more
TL;DR: Experts assembled to review, debate and summarize the challenges of IB validation and qualification produced 14 key recommendations for accelerating the clinical translation of IBs, which highlight the role of parallel (rather than sequential) tracks of technical validation, biological/clinical validation and assessment of cost-effectiveness.
Journal ArticleDOI
Production of hyperpolarized [1,4-13C2]malate from [1,4-13C2]fumarate is a marker of cell necrosis and treatment response in tumors
Ferdia A. Gallagher,Mikko I. Kettunen,De-En Hu,Pernille Rose Jensen,René in ‘t Zandt,Magnus Karlsson,Anna Gisselsson,Sarah K. Nelson,Timothy H. Witney,Sarah E. Bohndiek,Georg Hansson,Torben Peitersen,Mathilde H. Lerche,Kevin M. Brindle +13 more
TL;DR: The formation of hyperpolarized 13C-labeled malate from [1,4-13C2]fumarate appears to be a sensitive marker of tumor cell death in vivo and could be used to detect the early response of tumors to treatment.
Journal ArticleDOI
Tumor imaging using hyperpolarized 13C magnetic resonance spectroscopy
TL;DR: This review highlights the most significant molecules investigated to date in preclinical cancer models, either in terms of their demonstrated metabolism in vivo or the biological processes that they can probe, and techniques to image these molecules are discussed.
Journal ArticleDOI
Hyperpolarized [1-13C]-ascorbic and dehydroascorbic acid: vitamin C as a probe for imaging redox status in vivo.
Sarah E. Bohndiek,Mikko I. Kettunen,De-En Hu,Brett W. C. Kennedy,Joan Boren,Ferdia A. Gallagher,Kevin M. Brindle +6 more
TL;DR: This study demonstrates that hyperpolarized 13C-labeled vitamin C could be used as a noninvasive biomarker of redox status in vivo, which has the potential to translate to the clinic.