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Mitja I. Kurki

Researcher at Broad Institute

Publications -  125
Citations -  16418

Mitja I. Kurki is an academic researcher from Broad Institute. The author has contributed to research in topics: Population & Genome-wide association study. The author has an hindex of 30, co-authored 101 publications receiving 13209 citations. Previous affiliations of Mitja I. Kurki include Harvard University & Utrecht University.

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Analysis of protein-coding genetic variation in 60,706 humans

Monkol Lek, +106 more
- 18 Aug 2016 - 
TL;DR: The aggregation and analysis of high-quality exome (protein-coding region) DNA sequence data for 60,706 individuals of diverse ancestries generated as part of the Exome Aggregation Consortium (ExAC) provides direct evidence for the presence of widespread mutational recurrence.
Posted ContentDOI

Analysis of protein-coding genetic variation in 60,706 humans

Monkol Lek, +72 more
- 30 Oct 2015 - 
TL;DR: The aggregation and analysis of high-quality exome (protein-coding region) sequence data for 60,706 individuals of diverse ethnicities generated as part of the Exome Aggregation Consortium (ExAC) provides direct evidence for the presence of widespread mutational recurrence.
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Analysis of shared heritability in common disorders of the brain

Verneri Anttila, +720 more
- 22 Jun 2018 - 
TL;DR: It is demonstrated that, in the general population, the personality trait neuroticism is significantly correlated with almost every psychiatric disorder and migraine, and it is shown that both psychiatric and neurological disorders have robust correlations with cognitive and personality measures.
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Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine

Padhraig Gormley, +133 more
- 01 Aug 2016 - 
TL;DR: For example, the authors identified 44 independent single-nucleotide polymorphisms (SNPs) significantly associated with migraine risk (P < 5 × 10−8) that mapped to 38 distinct genomic loci, including 28 loci not previously reported and a locus that to date is the first to be identified on chromosome X.
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Rare loss-of-function variants in SETD1A are associated with schizophrenia and developmental disorders

Tarjinder Singh, +61 more
- 01 Apr 2016 - 
TL;DR: In this article, the authors found a genome-wide significant association between rare loss-of-function (LoF) variants in SETD1A and risk for schizophrenia (P = 3.3 × 10−9).