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Stephan Claes
Researcher at Katholieke Universiteit Leuven
Publications - 224
Citations - 8092
Stephan Claes is an academic researcher from Katholieke Universiteit Leuven. The author has contributed to research in topics: Population & DNA methylation. The author has an hindex of 42, co-authored 218 publications receiving 6682 citations. Previous affiliations of Stephan Claes include The Catholic University of America & Catholic University of Leuven.
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Journal ArticleDOI
The neuroactive potential of the human gut microbiota in quality of life and depression
Mireia Valles-Colomer,Mireia Valles-Colomer,Gwen Falony,Gwen Falony,Youssef Darzi,Youssef Darzi,Ettje F. Tigchelaar,Jun Wang,Jun Wang,Raul Y. Tito,Raul Y. Tito,Raul Y. Tito,Carmen Schiweck,Alexander Kurilshikov,Marie Joossens,Marie Joossens,Cisca Wijmenga,Cisca Wijmenga,Stephan Claes,Lukas Van Oudenhove,Alexandra Zhernakova,Sara Vieira-Silva,Sara Vieira-Silva,Jeroen Raes,Jeroen Raes +24 more
TL;DR: Correlation of microbiome features with host quality of life and depression identified specific taxa and microbial pathways in two independent, large population cohorts, identifying links between microbial neuroactive potential and depression.
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Genome scan meta-analysis of schizophrenia and bipolar disorder, part III: Bipolar disorder.
Ricardo Segurado,Sevilla D. Detera-Wadleigh,Douglas F. Levinson,Cathryn M. Lewis,Michael Gill,John I. Nurnberger,Nicholas John Craddock,J. Raymond DePaulo,Miron Baron,Elliot S. Gershon,Jenny Ekholm,Sven Cichon,Gustavo Turecki,Stephan Claes,John R. Kelsoe,Peter R. Schofield,Renee F. Badenhop,Renee F. Badenhop,Jean Morissette,Hilary Coon,Douglas Blackwood,L. Alison McInnes,Tatiana Foroud,Howard J. Edenberg,Theodore Reich,John P. Rice,Alison Goate,Melvin G. McInnis,Francis J. McMahon,Judith A. Badner,Lynn R. Goldin,Phil Bennett,Virginia L. Willour,Peter P. Zandi,Jianjun Liu,Conrad T. Gilliam,S H Juo,Wade H. Berrettini,Takeo Yoshikawa,Leena Peltonen,Leena Peltonen,Jouko Lönnqvist,Markus M. Nöthen,Johannes Schumacher,Christine Windemuth,Marcella Rietschel,Peter Propping,Wolfgang Maier,Martin Alda,Paul Grof,Guy A. Rouleau,Jurgen Del-Favero,Christine Van Broeckhoven,Julien Mendlewicz,Rolf Adolfsson,M. Anne Spence,Hermann Luebbert,L. J. Adams,Jennifer A. Donald,Philip B. Mitchell,Nicholas Barden,Eric Shink,William Byerley,Walter J. Muir,Peter M. Visscher,Stuart MacGregor,Hugh Gurling,Gursharan Kalsi,Andrew McQuillin,Michael Escamilla,Victor I. Reus,Pedro León,Nelson B. Freimer,Henrik Ewald,Torben A Kruse,Ole Mors,Uppala Radhakrishna,Jean-Louis Blouin,Stylianos E. Antonarakis,Nurten A. Akarsu +79 more
TL;DR: The present results for the very narrow model are promising but suggest that more and larger data sets are needed to support linkage, as well as suggest that linkage might be detected in certain populations or subsets of pedigrees.
Journal ArticleDOI
Meta-analyses of genetic studies on major depressive disorder.
Sandra Lopez-Leon,A C J W Janssens,A. M. González-Zuloeta Ladd,Jurgen Del-Favero,Stephan Claes,B.A. Oostra,C.M. van Duijn +6 more
TL;DR: All MDD case–control genetic association studies published before June 2007 are reviewed and meta-analyses for polymorphisms that had been investigated in at least three studies that found statistically significant associations are performed.
Journal ArticleDOI
Reduced Reward Learning predicts outcome in Major Depressive Disorder
Elske Vrieze,Diego A. Pizzagalli,Koen Demyttenaere,Titia Hompes,Pascal Sienaert,Peter de Boer,Mark E. Schmidt,Stephan Claes +7 more
TL;DR: Findings indicate that depressed patients, especially those with anhedonic features, are characterized by an impaired ability to modulate behavior as a function of reward, and reduced reward learning increased the odds for the diagnosis of MDD to persist after 8 weeks of treatment.
Journal ArticleDOI
Investigating the influence of maternal cortisol and emotional state during pregnancy on the DNA methylation status of the glucocorticoid receptor gene (NR3C1) promoter region in cord blood
Titia Hompes,Benedetta Izzi,Edith Gellens,Maarten Morreels,Steffen Fieuws,Steffen Fieuws,Anne Pexsters,Ganel Schops,Myriam Dom,Rieta Van Bree,Kathleen Freson,Johan Verhaeghe,Bernard Spitz,Koen Demyttenaere,Vivette Glover,Bea Van den Bergh,Bea Van den Bergh,Karel Allegaert,Stephan Claes +18 more
TL;DR: Preliminary data indicate that prenatal maternal emotional state, particularly pregnancy related anxiety, are associated with the methylation state of the NR3C1 gene in the child.