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Thomas A. Wynn
Researcher at University of California, San Diego
Publications - 300
Citations - 61781
Thomas A. Wynn is an academic researcher from University of California, San Diego. The author has contributed to research in topics: Cytokine & Schistosoma mansoni. The author has an hindex of 111, co-authored 276 publications receiving 52854 citations. Previous affiliations of Thomas A. Wynn include Los Alamos National Laboratory & Urbana University.
Papers
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Journal ArticleDOI
Nucleation of dislocations and their dynamics in layered oxide cathode materials during battery charging
Andrej Singer,Andrej Singer,Minghao Zhang,Sunny Hy,Devin Cela,Chengcheng Fang,Thomas A. Wynn,Bao Qiu,Y. Xia,Zhaoping Liu,Andrew Ulvestad,Nelson Hua,James Wingert,Haodong Liu,Michael Sprung,Alexey Zozulya,Alexey Zozulya,Evan Maxey,Ross Harder,Ying Shirley Meng,Oleg Shpyrko +20 more
TL;DR: In this paper, the authors reveal the link between voltage fade and nucleation of a mobile dislocation network in the oxide nanoparticles, offering design ideas to restore the voltage in the battery.
Journal ArticleDOI
Muc5ac: a critical component mediating the rejection of enteric nematodes
Sumaira Z. Hasnain,Christopher M. Evans,Michelle G. Roy,Amanda L. Gallagher,Kristen N. Kindrachuk,Luke Barron,Burton F. Dickey,Mark S. Wilson,Thomas A. Wynn,Richard K. Grencis,David J. Thornton +10 more
TL;DR: The mucin Muc5ac is essential for the expulsion of Trichuris muris and other gut-dwelling nematodes.
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Regulation and Function of the Interleukin 13 Receptor α 2 During a T Helper Cell Type 2–dominant Immune Response
Monica G. Chiaramonte,Margaret M. Mentink-Kane,Bruce A. Jacobson,Allen W. Cheever,Matthew J. Whitters,Mary E.P. Goad,Anthony Wong,Mary Collins,Debra D. Donaldson,Michael J. Grusby,Thomas A. Wynn +10 more
TL;DR: IL-13 receptor (R)α2 is a critical down-regulatory factor of IL-13–mediated tissue fibrosis induced by the parasitic helminth Schistosoma mansoni, illustrating the central role played by the IL- 13Rα2 in the down-regulation of a chronic and pathogenic Th2-mediated immune response.
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Global Gene Expression Profiles During Acute Pathogen-Induced Pulmonary Inflammation Reveal Divergent Roles for Th1 and Th2 Responses in Tissue Repair
TL;DR: Th1-mediated inflammation is characterized by tissue damage, while Th2 directs wound healing and fibrosis in this model of Th1- or Th2-type inflammation.
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Fibrosis is regulated by Th2 and Th17 responses and by dynamic interactions between fibroblasts and macrophages
Luke Barron,Thomas A. Wynn +1 more
TL;DR: The interactions among fibroblasts, macrophages, and CD4 T cells likely play general and critical roles in initiating, perpetuating, and resolving fibrosis in both experimental and clinical conditions.