T
Thomas F. Meyer
Researcher at University of Kiel
Publications - 3
Citations - 304
Thomas F. Meyer is an academic researcher from University of Kiel. The author has contributed to research in topics: Gene & Innate immune system. The author has an hindex of 2, co-authored 3 publications receiving 76 citations.
Papers
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Journal ArticleDOI
Transcriptomic profiling of SARS-CoV-2 infected human cell lines identifies HSP90 as target for COVID-19 therapy.
Emanuel Wyler,Kirstin Mösbauer,Vedran Franke,Asija Diag,Lina Theresa Gottula,Roberto Arsie,Filippos Klironomos,Filippos Klironomos,David Koppstein,Katja Hönzke,Salah Ayoub,Christopher Buccitelli,Karen Hoffmann,Anja Richter,Ivano Legnini,Andranik Ivanov,Tommaso Mari,Simone Del Giudice,Jan Papies,Samantha D. Praktiknjo,Thomas F. Meyer,Marcel A. Müller,Daniela Niemeyer,Andreas C. Hocke,Matthias Selbach,Altuna Akalin,Nikolaus Rajewsky,Christian Drosten,Markus Landthaler,Markus Landthaler +29 more
TL;DR: In this article, gene expression profiles of three SARS-CoV and SARS CoV-2 infected human cell lines were reported, and it was shown that SARS co-virus infection elicited an approximately two-fold higher stimulation of the innate immune response compared to SARS in the human epithelial cell line Calu-3, including induction of miRNA-155.
Journal ArticleDOI
SARS-CoV-2-mediated dysregulation of metabolism and autophagy uncovers host-targeting antivirals.
Nils C. Gassen,Jan Papies,Jan Papies,Thomas Bajaj,Jackson Emanuel,Jackson Emanuel,Frederik Dethloff,Robert Lorenz Chua,Jakob Trimpert,Nicolas Heinemann,Nicolas Heinemann,Christine Niemeyer,Friderike Weege,Friderike Weege,Katja Hönzke,Tom Aschman,Daniel E. Heinz,Katja Weckmann,Tim Ebert,Andreas Zellner,M. Lennarz,Emanuel Wyler,Simon Schroeder,Simon Schroeder,Anja Richter,Anja Richter,Daniela Niemeyer,Daniela Niemeyer,Karen Hoffmann,Thomas F. Meyer,Frank L. Heppner,Frank L. Heppner,Victor M. Corman,Victor M. Corman,Markus Landthaler,Markus Landthaler,Andreas C. Hocke,Markus Morkel,Markus Morkel,Nikolaus Osterrieder,Nikolaus Osterrieder,Christian Conrad,Roland Eils,Roland Eils,Helena Radbruch,Patrick Giavalisco,Christian Drosten,Christian Drosten,Marcel A. Müller +48 more
TL;DR: In this paper, the authors show that SARS-CoV-2 infection modulates cellular metabolism and limits autophagy, and identify druggable host pathways for virus inhibition.
Patent
Use of modulators of eukaryotic signal transduction pathways for the treatment of helicobacter infections
Steffen Backert,Michael Hoecker,Peter Jungblut,Thomas F. Meyer,Stefan Moese,Rama Rao Nalini,Michael Naumann,Matthias Selbach,Silja Wessler,Bertram Wiedenmann +9 more
TL;DR: In this paper, a method of treating a disorder in a mammalian cell or organism mediated by a Helicobacter infection where eukaryotic signal transduction pathways are inhibited is presented.