J
J. C. Trussell
Researcher at State University of New York Upstate Medical University
Publications - 13
Citations - 1171
J. C. Trussell is an academic researcher from State University of New York Upstate Medical University. The author has contributed to research in topics: Infertility & Polycystic ovary. The author has an hindex of 10, co-authored 11 publications receiving 925 citations.
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Journal ArticleDOI
Letrozole versus Clomiphene for Infertility in the Polycystic Ovary Syndrome
Richard S. Legro,Robert G. Brzyski,Michael P. Diamond,Christos Coutifaris,William D. Schlaff,Peter Casson,Gregory M. Christman,Hao Huang,Qingshang Yan,Ruben Alvero,Daniel J. Haisenleder,Kurt T. Barnhart,G. Wright Bates,Rebecca S. Usadi,Scott Lucidi,Valerie L. Baker,J. C. Trussell,Stephen A. Krawetz,Peter J. Snyder,Dana A. Ohl,Nanette Santoro,Esther Eisenberg,Heping Zhang +22 more
TL;DR: Letrozole was associated with higher live-birth and ovulation rates among infertile women with the polycystic ovary syndrome and with higher incidences of fatigue and dizziness compared with clomiphene.
Journal ArticleDOI
Genome-wide association of polycystic ovary syndrome implicates alterations in gonadotropin secretion in European ancestry populations
M. Geoffrey Hayes,Margrit Urbanek,David A. Ehrmann,Loren L. Armstrong,Ji Young Lee,Ryan Sisk,Tugce Karaderi,Thomas M. Barber,Mark I. McCarthy,Stephen Franks,Cecilia M. Lindgren,Cecilia M. Lindgren,Corrine K. Welt,Evanthia Diamanti-Kandarakis,Dimitrios Panidis,Mark O. Goodarzi,Ricardo Azziz,Yi Zhang,Roland James,Michael Olivier,Ahmed H. Kissebah,Elisabet Stener-Victorin,Richard S. Legro,Andrea Dunaif,Ruben Alvero,Huiman X. Barnhart,Valerie L. Baker,Kurt T. Barnhart,G. Wright Bates,Robert G. Brzyski,Bruce R. Carr,Sandra Ann Carson,Peter R. Casson,Nicholas A. Cataldo,Gregory M. Christman,Christos Coutifaris,Michael P. Diamond,Esther Eisenberg,Gabriella G. Gosman,Linda C. Giudice,Daniel J. Haisenleder,Hao Huang,Stephen A. Krawetz,Scott Lucidi,Peter G. McGovern,Evan R. Myers,John E. Nestler,Dana A. Ohl,Nanette Santoro,William D. Schlaff,Peter J. Snyder,Michael P. Steinkampf,J. C. Trussell,Rebecca S. Usadi,Qingshang Yan,Heping Zhang +55 more
TL;DR: Common genetic susceptibility loci in European ancestry women for the National Institutes of Health PCOS phenotype are identified, which confers the highest risk for metabolic morbidities, as well as reproductive hormone levels, and implicate neuroendocrine changes in disease pathogenesis.
Journal ArticleDOI
Letrozole, Gonadotropin, or Clomiphene for Unexplained Infertility
Michael P. Diamond,Richard S. Legro,Christos Coutifaris,Ruben Alvero,Randal D. Robinson,Peter Casson,Gregory M. Christman,Joel W. Ager,Hao Huang,Karl R. Hansen,Valerie L. Baker,Rebecca S. Usadi,Aimee Seungdamrong,G.W. Bates,R. M. Rosen,Daniel J. Haisenleder,Stephen A. Krawetz,Kurt T. Barnhart,J. C. Trussell,Dana A. Ohl,Yufeng Jin,Nanette Santoro,Esther Eisenberg,Heping Zhang +23 more
TL;DR: In women with unexplained infertility, ovarian stimulation with letrozole resulted in a significantly lower frequency of multiple gestation but also a higher frequency of live birth, as compared with gonadotropin but not asCompared with clomiphene.
Journal ArticleDOI
The Pregnancy in Polycystic Ovary Syndrome II study: baseline characteristics and effects of obesity from a multicenter randomized clinical trial.
Richard S. Legro,Robert G. Brzyski,Michael P. Diamond,Christos Coutifaris,William D. Schlaff,Ruben Alvero,Peter Casson,Gregory M. Christman,Hao Huang,Qingshang Yan,Daniel J. Haisenleder,Kurt T. Barnhart,G. Wright Bates,Rebecca S. Usadi,Richard S. Lucidi,Valerie L. Baker,J. C. Trussell,Stephen A. Krawetz,Peter J. Snyder,Dana A. Ohl,Nanette Santoro,Esther Eisenberg,Heping Zhang +22 more
TL;DR: Obesity exacerbates select female reproductive and most metabolic parameters and is associated with decreased LH-to-FSH levels, antimüllerian hormone levels, and antral follicle counts but increasing cardiovascular risk factors, including prevalence of the metabolic syndrome.
Journal ArticleDOI
Fertility-related quality of life from two RCT cohorts with infertility: unexplained infertility and polycystic ovary syndrome.
Nanette Santoro,Esther Eisenberg,J. C. Trussell,LaTasha B. Craig,Clarisa R. Gracia,Hao Huang,Ruben Alvero,Ruben Alvero,Peter R. Casson,Gregory M. Christman,Christos Coutifaris,Michael P. Diamond,Susan Jin,Richard S. Legro,Randal D. Robinson,William D. Schlaff,Heping Zhang +16 more
TL;DR: Women with PCOS with elevated BMI and hirsutism scores and with lower socioeconomic status may require more, targeted psychosocial support than those with other diagnoses, and appear to result in a lower FertiQOL.