M
Michael Olivier
Researcher at Wake Forest University
Publications - 101
Citations - 5973
Michael Olivier is an academic researcher from Wake Forest University. The author has contributed to research in topics: Single-nucleotide polymorphism & Mass spectrometry. The author has an hindex of 34, co-authored 99 publications receiving 5342 citations. Previous affiliations of Michael Olivier include Wake Forest Baptist Medical Center & University of Wisconsin-Madison.
Papers
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Journal ArticleDOI
An Apolipoprotein Influencing Triglycerides in Humans and Mice Revealed by Comparative Sequencing
Len A. Pennacchio,Michael Olivier,Jaroslav A. Hubacek,Jonathan Cohen,David R. Cox,Jean-Charles Fruchart,Ronald M. Krauss,Edward M. Rubin +7 more
TL;DR: Findings indicate that APOAV is an important determinant of plasma triglyceride levels, a major risk factor for coronary artery disease.
Journal ArticleDOI
Two independent apolipoprotein A5 haplotypes influence human plasma triglyceride levels
Len A. Pennacchio,Michael Olivier,Jaroslav A. Hubacek,Ronald M. Krauss,Edward M. Rubin,Jonathan Cohen +5 more
TL;DR: It is established that the APOA5 locus contributes significantly to inter-individual variation in plasma triglyceride levels in humans.
Journal ArticleDOI
Relative contribution of variation within the APOC3/A4/A5 gene cluster in determining plasma triglycerides
Philippa J. Talmud,Emma Hawe,S Martin,Michael Olivier,George J. Miller,Edward M. Rubin,Len A. Pennacchio,Steve E. Humphries +7 more
TL;DR: Variation in APOA5 is associated with differences in TGs in healthy men, independent of those previously reported for APOC3, while association between APOA4 and TG reflects linkage disequilibrium with these sites.
Journal ArticleDOI
High-Throughput Genotyping with Single Nucleotide Polymorphisms
Koustubh Ranade,Mau-Song Chang,Chih-Tai Ting,Dee Pei,Chin-Fu Hsiao,Michael Olivier,Robert Pesich,Joan M. Hebert,Yii-Der Ida Chen,Victor J. Dzau,David Curb,Richard A. Olshen,Neil Risch,David Cox,David Botstein +14 more
TL;DR: PCR conditions that permit the use of the TaqMan or 5' nuclease allelic discrimination assay for typing large numbers of individuals with any SNP and computational methods that allow genotypes to be assigned automatically are described.
Journal ArticleDOI
Genome-wide association of polycystic ovary syndrome implicates alterations in gonadotropin secretion in European ancestry populations
M. Geoffrey Hayes,Margrit Urbanek,David A. Ehrmann,Loren L. Armstrong,Ji Young Lee,Ryan Sisk,Tugce Karaderi,Thomas M. Barber,Mark I. McCarthy,Stephen Franks,Cecilia M. Lindgren,Cecilia M. Lindgren,Corrine K. Welt,Evanthia Diamanti-Kandarakis,Dimitrios Panidis,Mark O. Goodarzi,Ricardo Azziz,Yi Zhang,Roland James,Michael Olivier,Ahmed H. Kissebah,Elisabet Stener-Victorin,Richard S. Legro,Andrea Dunaif,Ruben Alvero,Huiman X. Barnhart,Valerie L. Baker,Kurt T. Barnhart,G. Wright Bates,Robert G. Brzyski,Bruce R. Carr,Sandra Ann Carson,Peter R. Casson,Nicholas A. Cataldo,Gregory M. Christman,Christos Coutifaris,Michael P. Diamond,Esther Eisenberg,Gabriella G. Gosman,Linda C. Giudice,Daniel J. Haisenleder,Hao Huang,Stephen A. Krawetz,Scott Lucidi,Peter G. McGovern,Evan R. Myers,John E. Nestler,Dana A. Ohl,Nanette Santoro,William D. Schlaff,Peter J. Snyder,Michael P. Steinkampf,J. C. Trussell,Rebecca S. Usadi,Qingshang Yan,Heping Zhang +55 more
TL;DR: Common genetic susceptibility loci in European ancestry women for the National Institutes of Health PCOS phenotype are identified, which confers the highest risk for metabolic morbidities, as well as reproductive hormone levels, and implicate neuroendocrine changes in disease pathogenesis.