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Ruben Alvero
Researcher at Stanford University
Publications - 106
Citations - 2967
Ruben Alvero is an academic researcher from Stanford University. The author has contributed to research in topics: Infertility & Polycystic ovary. The author has an hindex of 21, co-authored 93 publications receiving 2402 citations. Previous affiliations of Ruben Alvero include University of Colorado Boulder & National Institutes of Health.
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Journal ArticleDOI
Letrozole versus Clomiphene for Infertility in the Polycystic Ovary Syndrome
Richard S. Legro,Robert G. Brzyski,Michael P. Diamond,Christos Coutifaris,William D. Schlaff,Peter Casson,Gregory M. Christman,Hao Huang,Qingshang Yan,Ruben Alvero,Daniel J. Haisenleder,Kurt T. Barnhart,G. Wright Bates,Rebecca S. Usadi,Scott Lucidi,Valerie L. Baker,J. C. Trussell,Stephen A. Krawetz,Peter J. Snyder,Dana A. Ohl,Nanette Santoro,Esther Eisenberg,Heping Zhang +22 more
TL;DR: Letrozole was associated with higher live-birth and ovulation rates among infertile women with the polycystic ovary syndrome and with higher incidences of fatigue and dizziness compared with clomiphene.
Journal ArticleDOI
The morphology of human pronuclear embryos is positively related to blastocyst development and implantation
TL;DR: Zygote scoring can maintain pregnancy rates for both day 3 and day 5 transfers, increase implantation rates and reduce the numbers of embryos required to achieve a pregnancy.
Journal ArticleDOI
Genome-wide association of polycystic ovary syndrome implicates alterations in gonadotropin secretion in European ancestry populations
M. Geoffrey Hayes,Margrit Urbanek,David A. Ehrmann,Loren L. Armstrong,Ji Young Lee,Ryan Sisk,Tugce Karaderi,Thomas M. Barber,Mark I. McCarthy,Stephen Franks,Cecilia M. Lindgren,Cecilia M. Lindgren,Corrine K. Welt,Evanthia Diamanti-Kandarakis,Dimitrios Panidis,Mark O. Goodarzi,Ricardo Azziz,Yi Zhang,Roland James,Michael Olivier,Ahmed H. Kissebah,Elisabet Stener-Victorin,Richard S. Legro,Andrea Dunaif,Ruben Alvero,Huiman X. Barnhart,Valerie L. Baker,Kurt T. Barnhart,G. Wright Bates,Robert G. Brzyski,Bruce R. Carr,Sandra Ann Carson,Peter R. Casson,Nicholas A. Cataldo,Gregory M. Christman,Christos Coutifaris,Michael P. Diamond,Esther Eisenberg,Gabriella G. Gosman,Linda C. Giudice,Daniel J. Haisenleder,Hao Huang,Stephen A. Krawetz,Scott Lucidi,Peter G. McGovern,Evan R. Myers,John E. Nestler,Dana A. Ohl,Nanette Santoro,William D. Schlaff,Peter J. Snyder,Michael P. Steinkampf,J. C. Trussell,Rebecca S. Usadi,Qingshang Yan,Heping Zhang +55 more
TL;DR: Common genetic susceptibility loci in European ancestry women for the National Institutes of Health PCOS phenotype are identified, which confers the highest risk for metabolic morbidities, as well as reproductive hormone levels, and implicate neuroendocrine changes in disease pathogenesis.
Journal ArticleDOI
Letrozole, Gonadotropin, or Clomiphene for Unexplained Infertility
Michael P. Diamond,Richard S. Legro,Christos Coutifaris,Ruben Alvero,Randal D. Robinson,Peter Casson,Gregory M. Christman,Joel W. Ager,Hao Huang,Karl R. Hansen,Valerie L. Baker,Rebecca S. Usadi,Aimee Seungdamrong,G.W. Bates,R. M. Rosen,Daniel J. Haisenleder,Stephen A. Krawetz,Kurt T. Barnhart,J. C. Trussell,Dana A. Ohl,Yufeng Jin,Nanette Santoro,Esther Eisenberg,Heping Zhang +23 more
TL;DR: In women with unexplained infertility, ovarian stimulation with letrozole resulted in a significantly lower frequency of multiple gestation but also a higher frequency of live birth, as compared with gonadotropin but not asCompared with clomiphene.
Journal ArticleDOI
Altered microRNA and gene expression in the follicular fluid of women with polycystic ovary syndrome
Lauren W. Roth,Blair R. McCallie,Ruben Alvero,William B. Schoolcraft,D.A. Minjarez,Mandy G. Katz-Jaffe +5 more
TL;DR: MicroRNAs are differentially expressed in the follicular fluid of women with PCOS when compared to fertile oocyte donors and there is also altered expression of potential target genes associated with the PCOS phenotype.