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William C. Hahn
Researcher at Harvard University
Publications - 515
Citations - 85047
William C. Hahn is an academic researcher from Harvard University. The author has contributed to research in topics: Cancer & Medicine. The author has an hindex of 130, co-authored 448 publications receiving 72191 citations. Previous affiliations of William C. Hahn include Brigham and Women's Hospital & University of Washington.
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Journal ArticleDOI
Naked DNA expressing two isoforms of hepatocyte growth factor induces collateral artery augmentation in a rabbit model of limb ischemia
Wook-Bum Pyun,William C. Hahn,D. S. Kim,W. S. Yoo,S. D. Lee,J. H. Won,B. S. Rho,Z. Y. Park,Jungkon Kim,Sunyoung Kim +9 more
TL;DR: Results showed that transfer of the genomic–cDNA hybrid of the HGF gene could be used as a potential therapeutic approach to human vascular diseases.
Journal ArticleDOI
The Role of PP2A A Subunits in Tumor Suppression
Anna Sablina,William C. Hahn +1 more
TL;DR: Observations provide evidence that dysfunction of particular PP2A complexes regulate specific phosphorylation event necessary for cancer initiation.
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Developing a library of authenticated Traditional Chinese Medicinal (TCM) plants for systematic biological evaluation — Rationale, methods and preliminary results from a Sino-American collaboration
David Eisenberg,Eric S. J. Harris,Bruce A. Littlefield,Shugeng Cao,Jane A. Craycroft,Robert Scholten,Peter E. Bayliss,Yanling Fu,Wenquan Wang,Yanjiang Qiao,Zhongzhen Zhao,Hubiao Chen,Yong Liu,Ted J. Kaptchuk,William C. Hahn,Xiaoxing Wang,Thomas M. Roberts,Caroline E. Shamu,Jon Clardy +18 more
TL;DR: This manuscript summarizes the rationale, methods and preliminary "proof of principle" for the establishment of this prototype, authenticated medicinal plant library and it is hoped that these methods will foster scientific discoveries with therapeutic potential and enhance efforts to systematically evaluate commonly used herbal therapies worldwide.
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High Throughput Interrogation of Somatic Mutations in High Grade Serous Cancer of the Ovary
Ursula A. Matulonis,Michelle S. Hirsch,Emanuele Palescandolo,Eejung Kim,Joyce F. Liu,Paul Van Hummelen,Laura E. MacConaill,Ronny Drapkin,Ronny Drapkin,William C. Hahn +9 more
TL;DR: Sequenom analysis using OncoMap on DNA extracted from FFPE ovarian cancer samples is feasible and leads to the detection of potentially druggable mutations.
Journal Article
Signal transduction pathways involved in T cell receptor-induced regulation of CD2 avidity for CD58.
TL;DR: Analysis of physiologic interactions with its ligands CD58 and T cell glycoprotein CD2 identifies the signaling events involved in the regulation of CD2 avidity and helps to define the signal transduction processes that participate in "inside-out" signaling.