Abdou Moumouni University

About: Abdou Moumouni University is a education organization based out in Niamey, Niamey, Niger. It is known for research contribution in the topics: Population & Agriculture. The organization has 796 authors who have published 808 publications receiving 17478 citations. The organization is also known as: University of Niamey & Abdou Moumouni Dioffo University.

Clinical and Etiological Characteristics of Epilepsy in the Elderly: A Hospital-Based Study from a Tertiary Care Referral Center of Niamey, Niger.

Abstract: Objectives The aim of this study is to evaluate the management of epilepsy in the elderly at a tertiary referral center in Niger to obtain a comprehensive understanding to determine the intrahospital deficiencies to improve and to make recommendations in terms to improve the management of epilepsy in the elderly in Niger. Materials and Methods We conducted a retrospective study at the Neurology Outpatient Clinic of the National Hospital of Niamey (Niger) over a period of 5 years from May 2013 to May 2018, collecting all cases of patients aged 60 years or over diagnosed with epilepsy by neurologists. From the registers of consultation, we collected and analyzed for each patient the demographic, clinical, etiological, and therapeutic data, as well as the outcomes during follow-up visits. Results Of the 4,576 patients of all ages seen during the period of our study, we included 62 patients aged 60 years or over diagnosed with epilepsy with a hospital frequency of 1.35%. The mean age of patients was 65.82 ± 5.72 years (range: 60 and 83 years) with a predominance of the male sex (sex ratio at 1.6). Patients aged 60 to 64 years were the most represented (43.5%). Generalized tonic–clonic seizures were the most frequent (41.9%), followed by focal to bilateral tonic-clonic seizures (25.8%). All patients underwent electroencephalogram. Only 30 patients (48.4%) underwent brain imaging, and mainly brain computed tomography scan. The etiologies included poststroke epilepsy (25.8%), brain tumors (3.2%), cerebral toxoplasmosis (3.2%), and cerebral meningioma (1.6%). We found 41 cases (66.1%) of epilepsy without definite etiology and with an incomplete workup. Carbamazepine and phenobarbital were the only two antiepileptic drugs (AEDs) used. Conclusion The present study shows limited access to newer generation AEDs and diagnostic tests of epilepsy in Niger. Considerable efforts should be made to facilitate for people living with epilepsy the accessibility to diagnostic tests and the newer generation AEDs to improve the quality of epilepsy management in Niger.

Amelioration Du Rendement Du Mil Par L’association Avec Le Niebe En Zone Sahelienne

Abstract: In Niger, agricultural production is based mainly on the association and rotation grains / legumes with generally low yields. To improve these yields, seeding effects and cowpea genotypes in combination with millet were studied in 2014 and 2015 in the Sahel region of Niger. The experimental device is a split plot design with three replications. cowpea genotypes were large plots, and two seeding (1: 1 and 1: 2, millet and cowpea) in small plots. In addition, four parcels of pure millet grown in the past two years have been used as control. Analysis of variance revealed that for cowpea, biomass yield, seed, weight of hundred seeds and seed harvest index were significantly affected by the genotypes for two years. However, there is no significant effect on the density and cowpea genotypes on grain yields of millet. In 2014, the biomass yield millet density 2 was lower than the density of one. The density 2 increased yields of cowpea and millet slightly diminish those.

Biannual versus annual mass azithromycin distribution and malaria seroepidemiology among preschool children in Niger: a sub-study of a cluster randomized trial

Abstract: Biannual mass azithromycin administration to preschool children reduces all-cause mortality, but the mechanism for the effect is not understood. Azithromycin has activity against malaria parasites, and malaria is a leading cause of child mortality in the Sahel. The effect of biannual versus annual azithromycin distribution for trachoma control on serological response to merozoite surface protein 1 (MSP-119), a surrogate for malaria incidence, was evaluated among children in Niger. Markers of malaria exposure were measured in two arms of a factorial randomized controlled trial designed to evaluate targeted biannual azithromycin distribution to children under 12 years of age compared to annual azithromycin to the entire community for trachoma control (N = 12 communities per arm). Communities were treated for 36 months (6 versus 3 distributions). Dried blood spots were collected at 36 months among children ages 1–5 years, and MSP-119 antibody levels were assessed using a bead-based multiplex assay to measure malaria seroprevalence. Antibody results were available for 991 children. MSP-119 seropositivity was 62.7% in the biannual distribution arm compared to 68.7% in the annual arm (prevalence ratio 0.91, 95% CI 0.83 to 1.00). Mean semi-quantitative antibody levels were lower in the biannual distribution arm compared to the annual arm (mean difference − 0.39, 95% CI − 0.05 to − 0.72). Targeted biannual azithromycin distribution was associated with lower malaria seroprevalence compared to that in a population that received annual distribution. Trial Registration Clinicaltrials.gov NCT00792922

Re-Os Ages for the Kourki Porphyry Cu-Mo Deposits, North West Niger (West Africa): Geodynamic Implications

Abstract: The study area is located at the southern end of the Gorouol greenstone belt, northwestern Niger. This region contains significant deposits of Copper and Molybdenum hosted in intrusive rocks metamorphosed in the green shale facies. This deposit was previously considered a porphyry system of Copper (Cu) and Molybdenum (Mo) without having been the subject of advanced research. The objective of this study is to confirm or refute this hypothesis and to date the mineralisation in an absolute manner in order to readjust the mineralising episode in the history of the West African Craton. The methodology used within the framework of this study is the isotopic dating by the Re-Os method carried out on the pyrites of the host rock. The results of this analysis give an age range between 2158 ± 50 Ma and 2110 ± 51 Ma for the Cu-Mo mineralisation. This age range represents the West African Craton scale to an episode of magmatic accretion. During this accretion, the subduction phenomena between the Crusts (Oceanic and Continental) would have been favourable for the formation of the Cu and Mo mineralisation of Kourki.

Vegetative Propagation of Balanites aegyptiaca (L.) Del. by Air Layering under Sahelian Climate in Niger

Abstract: Balanites aegyptiaca (L.) Del. is a fruit species from the Sahelian and Sudano-sahelian zones, highly appreciated by the population. It provides a source of income for the rural population and its various parts are used for human and animal food, handicrafts and traditional medicine. However, the lack of data on propagation techniques of the species is a significant limitation to its domestication. This study aims to evaluate the vegetative propagation capacity of Balanites aegyptiaca by air layering. The trials were conducted in the Arboretum of Sahara Sahel Foods in Zinder, Niger. The layers were placed on orthotropic branches. The variables selected were the diameter class (1-2 cm, 2-3 cm and 3-4 cm) and the substrates (sand+manure, sand+sawdust and sand). A total of 116 layers were made. The results show that 93.1% of the layers have taken root two months after realization. The diameter classes and the three substrates have no significant influence on the number of roots. In contrast, root length varied significantly with substrates (P = 0.000) and branch diameter classes (P = 0.031). As for the diameter of the newly formed roots, a significant difference was observed between the diameter classes and the substrates have no significant effect on this parameter. One month after weaning of layers, an average survival rate of 68.5% was obtained. The seedlings of the diameter class 2-3 cm have the highest survival rate (83.1%). These results suggest that it is possible to produce Balanites aegyptiaca plants by air layering, and could contribute to the development of strategies adapted to its domestication.