Binzhou Medical College

About: Binzhou Medical College is a education organization based out in Yantai, China. It is known for research contribution in the topics: Apoptosis & Cancer. The organization has 959 authors who have published 619 publications receiving 7642 citations.

Effects of structural psychological nursing on sense of uncertainty and adverse cardiovascular events in patients with PCI

Abstract: Objective To investigate the effects of the structural psychological nursing on the sense of uncertainty and adverse cardiovascular events (ACE) in patients with PCI. Methods Totals of 98 PCI patients who admitted to the Cardiology Department of Affiliated Hospital of Binzhou Medical College from June 2015 to May 2016 were selected into the study. The participants were divided into the control group (n=49) and the intervention group (n=49) according to a random number table. Based on the routine nursing care, the intervention group received an additional structural psychological care. To compare the state of pre operative mood and post operative mood, the sense of uncertainty one day before and after PCI, and the incidence of ACE three months after PCI between the two groups. Results Patients in the intervention group had a better state of mood after the intervention compared with the control group. The sense of uncertainty was similar before the operation (P>0.05) but was significantly different between the two groups after the operation (t=4.635, 3.265, 4.012; P 0.05) . Conclusions The structural psychological nursing can effectively prevent the sense of uncertainty and adverse cardiovascular events in patients with PCI. Key words: Structural psychological nursing; Percutaneous coronary intervention; Sense of uncertainty; Adverse events

Changes of serum uric acid, bilirubin and homocysteine levels in patients with early Parkinson’s disease

Abstract: 目的 观察早期帕金森病并伴有轻度认知功能障碍（PD-MCI）患者血清间接胆红素（IBIL）、尿酸（UA）、同型半胱氨酸（Hcy）及尿酸/同型半胱氨酸比值（UA/Hcy）的变化，探讨其与PD-MCI的关系。 方法 收集158例早期未经药物治疗的帕金森病（PD）患者的人口学及临床资料，应用Hoehn & Yahr分级评估PD严重程度，MDS-UPDRS III评估运动障碍，蒙特利尔认知评估量表（MoCA）评估全面认知功能状态。102例年龄匹配的健康体检者作为对照组。检测各组血清IBIL、UA及Hcy含量，并计算UA/Hcy比值。 结果 158例早期PD患者中71例（44.9%）存在PD-MCI，87例（55.1%）无认知功能障碍（ P D-NCI）；两组患者MoCA评分差异有统计学意义（ P 0.05)。PD组、PD-MCI组、PD-NCI组UA含量均显著低于对照组（ P <0.01），PD-NCI组UA含量显著高于PD-MCI组（ P <0.01）。PD-MCI组Hcy含量显著高于对照组（ P <0.05）及PD-NCI组（ P <0.05）。IBIL、UA及UA/Hcy比值对预测PD-MCI均具有较好价值，且UA/Hcy比值较IBIL、UA预测价值更高。 结论 早期PD患者血清IBIL和UA水平显著降低，PD-MCI患者血IBIL和UA水平降低更显著，且伴有Hcy升高。IBIL、UA及UA/Hcy比值对预测PD-MCI均具有较好的价值，且UA/Hcy比值较IBIL、UA预测价值更高，UA/Hcy比值有可能成为潜在的生物标记物用于早期PD-MCI的预测。