Institution
Catholic University of the Sacred Heart
Education•Milan, Lombardia, Italy•
About: Catholic University of the Sacred Heart is a education organization based out in Milan, Lombardia, Italy. It is known for research contribution in the topics: Population & Medicine. The organization has 13592 authors who have published 31048 publications receiving 853961 citations.
Topics: Population, Medicine, Cancer, Health care, Myocardial infarction
Papers published on a yearly basis
Papers
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University of Toronto1, Hannover Medical School2, Geneva College3, Pontifical Bolivarian University4, Alfred Hospital5, Peking Union Medical College6, Catholic University of the Sacred Heart7, University of Genoa8, King Abdulaziz University9, Bombay Hospital, Indore10, University of Ulsan11, Medisch Centrum Leeuwarden12, University of Copenhagen13, University of Texas Health Science Center at San Antonio14
TL;DR: Patient characteristics and ventilation practices have changed over time, and outcomes of mechanically ventilated patients have improved, and crude mortality in the intensive care unit decreased in 2010 compared with 1998.
Abstract: Rationale: Baseline characteristics and management have changed over time in patients requiring mechanical ventilation; however, the impact of these changes on patient outcomes is unclear.Objectives: To estimate whether mortality in mechanically ventilated patients has changed over time.Methods: Prospective cohort studies conducted in 1998, 2004, and 2010, including patients receiving mechanical ventilation for more than 12 hours in a 1-month period, from 927 units in 40 countries. To examine effects over time on mortality in intensive care units, we performed generalized estimating equation models.Measurements and Main Results: We included 18,302 patients. The reasons for initiating mechanical ventilation varied significantly among cohorts. Ventilatory management changed over time (P < 0.001), with increased use of noninvasive positive-pressure ventilation (5% in 1998 to 14% in 2010), a decrease in tidal volume (mean 8.8 ml/kg actual body weight [SD = 2.1] in 1998 to 6.9 ml/kg [SD = 1.9] in 2010), and an...
537 citations
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TL;DR: The authors investigated the relation between ownership structure and firm performance in Continental Europe, using data from 675 publicly traded corporations in 11 countries and found that family-controlled corporations exhibit larger separation between control and cash-flow rights.
Abstract: We investigate the relation between ownership structure and firm performance in Continental Europe, using data from 675 publicly traded corporations in 11 countries. Although family-controlled corporations exhibit larger separation between control and cash-flow rights, our results do not support the hypothesis that family control hampers firm performance. Valuation and operating performance are significantly higher in founder-controlled corporations and in corporations controlled by descendants who sit on the board as non-executive directors. When a descendant takes the position of CEO, family-controlled companies are not statistically distinguishable from non-family firms in terms of valuation and performance.
537 citations
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TL;DR: This review presents seven lines of evidence that strongly suggest a link between the aftereffects induced by rTMS and the induction of synaptic plasticity, and provides suggestions for future, innovating research, aiming to investigate both the local effects of rT MS on the synapse and the effects of RTMS on other, more global levels of brain organization.
528 citations
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TL;DR: The developing gene- and cell-based bone regenerative approaches are described as promising future trends in spine fusion in a review of regenerative medicine.
Abstract: Bone fusion represents a challenge in the orthopedics practice, being especially indicated for spine disorders. Spinal fusion can be defined as the bony union between two vertebral bodies obtained through the surgical introduction of an osteoconductive, osteoinductive, and osteogenic compound. Autogenous bone graft provides all these three qualities and is considered the gold standard. However, a high morbidity is associated with the harvest procedure. Intensive research efforts have been spent during the last decades to develop new approaches and technologies for successful spine fusion. In recent years, cell and gene therapies have attracted great interest from the scientific community. The improved knowledge of both mesenchymal stem cell biology and osteogenic molecules allowed their use in regenerative medicine, representing attractive approaches to achieve bone regeneration also in spinal surgery applications. In this review we aim to describe the developing gene- and cell-based bone regenerative approaches as promising future trends in spine fusion.
528 citations
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TL;DR: The designs and rationals of the frailty phenotype and Frailty Index are discussed, proposing the correct ways for having them implemented in the clinical setting.
Abstract: The integration of frailty measures in clinical practice is crucial for the development of interventions against disabling conditions in older persons. The frailty phenotype (proposed and validated by Fried and colleagues in the Cardiovascular Health Study) and the Frailty Index (proposed and validated by Rockwood and colleagues in the Canadian Study of Health and Aging) represent the most known operational definitions of frailty in older persons. Unfortunately, they are often wrongly considered as alternatives and/or substitutables. These two instruments are indeed very different and should rather be considered as complementary. In the present paper, we discuss about the designs and rationals of the two instruments, proposing the correct ways for having them implemented in the clinical setting.
521 citations
Authors
Showing all 13795 results
Name | H-index | Papers | Citations |
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Peter J. Barnes | 194 | 1530 | 166618 |
Cornelia M. van Duijn | 183 | 1030 | 146009 |
Dennis R. Burton | 164 | 683 | 90959 |
Paolo Boffetta | 148 | 1455 | 93876 |
Massimo Antonelli | 130 | 1272 | 79319 |
David B. Audretsch | 126 | 671 | 72456 |
Piero Anversa | 115 | 412 | 60220 |
Marco Pahor | 112 | 476 | 46549 |
David L. Paterson | 111 | 739 | 68485 |
Alfonso Caramazza | 108 | 451 | 39280 |
Anthony A. Amato | 105 | 911 | 57881 |
Stefano Pileri | 100 | 635 | 43369 |
Giovanni Gasbarrini | 98 | 894 | 36395 |
Giampaolo Merlini | 96 | 684 | 40324 |
Silvio Donato | 96 | 860 | 41166 |