China Three Gorges University

About: China Three Gorges University is a education organization based out in Yichang, China. It is known for research contribution in the topics: Catalysis & Landslide. The organization has 11161 authors who have published 8011 publications receiving 82224 citations. The organization is also known as: Sanxia Daxue.

A Hybrid Forecasting Model for Short-Term Power Load Based on Sample Entropy, Two-Phase Decomposition and Whale Algorithm Optimized Support Vector Regression

Abstract: To improve the accuracy and reliability of short-term power load forecasting and reduce the difficulty caused by load volatility and non-linearity, a hybrid forecasting model (CEEMDAN-SE-VMD-PSR-WOA-SVR) is proposed. Firstly, the complete ensemble empirical mode decomposition with adaptive noise (CEEMDAN) is employed to generate multiple intrinsic modal functions (IMF) by decomposing the historical power load series. Then the sample entropy (SE) of each IMF is calculated to quantitatively evaluate the corresponding complexity. Afterward, variational mode decomposition (VMD) is adopted to achieve secondary decomposition for the component with the maximum sample entropy. Subsequently, the phase space reconstruction (PSR) is applied to reconstruct each IMF into a high-dimensional feature space matrix, which is formed as the input of support vector regression (SVR). Finally, SVR optimized by whale optimization algorithm (WOA) is used for the prediction, where the predicted values of all IMFs are accumulated to obtain the final prediction results. The experimental result demonstrates that the proposed hybrid model can effectively decompose the load series with non-linear characteristic and provide more accurate forecasting results by comparing the other models.

Down-Regulation of miR-327 Alleviates Ischemia/Reperfusion-Induced Myocardial Damage by Targeting RP105.

Abstract: Background/Aims: Micro RNAs (miRNAs) play a very important role in myocardial ischemia/ reperfusion injury (MIRI), including in inflammation, apoptosis, and angiogenesis Previous studies have demonstrated up-regulation of miR-327 in renal ischemia/reperfusion injury and MIRI Via TargetScan, we found RP105 is a possible target gene of miR-327; our previous studies have also confirmed that RP105 acted as a cardioprotective protein in MIRI by reducing inflammation However, the regulatory effect of miR-327 on RP105 has not previously been proposed In our study, we aimed to identify the regulatory effect of miR-327 on RP105 protein in MIRI rats Methods: Sixty male Sprague–Dawley rats were randomly divided into five groups, which were pre-treated with saline (sham and ischemia/reperfusion group), adenovirus-expressing miR-327-RNAi (Ad-miR-327-i group), control (Ad-NC group), or pri-miR-327 (Ad-miR-327 group) treatments Three days later, the rat MIRI model was established by ischemia for 30 min, followed by reperfusion for 3 h Myocardium and plasma were harvested and assessed Results: miR-327 was increased by nearly 3-fold both in myocardium and plasma, which down-regulated RP105 in a 3′-untranslated region-dependent manner, and down-regulation of miR-327 via adenovirus transfection indirectly suppressed the TLR4/ TLR2-MyD88-NF-κB signaling axis activation via up-regulation of RP105, which subsequently resulted in reduced myocardial infarct size, attenuated cardiomyocyte destruction, and alleviated inflammation In contrast, up-regulation of miR-327 induced the opposite effect Conclusion: Down-regulation of miR-327 exerts a cardioprotective effect against MIRI by reducing inflammation, which may constitute a promising molecular therapeutic target for treating MIRI