China Three Gorges University

About: China Three Gorges University is a education organization based out in Yichang, China. It is known for research contribution in the topics: Catalysis & Landslide. The organization has 11161 authors who have published 8011 publications receiving 82224 citations. The organization is also known as: Sanxia Daxue.

Environmental impact of phosphate mining and beneficiation: review

Abstract: Although the subject of mining and its environmental impacts are very wide to be covered in this review concerns about the impact of phosphate mining and processing typically emphasis on its potential effects on water pollution air pollution and human health were accessed We reviewed published information at different stages of mining current mines closed old mines and reclaimed mines and at different complexity of mining surface mining underground mining and sea bed phosphorite mining Information was analyzed to understand the association of toxic metals and radioactive elements in the phosphate rocks and to trace the transfer pathways of toxic metals and radioactive elements from the phosphate rocks to the environment According to the reviewed results the major environmental impacts of phosphate mining and processing on the water resources were impacts on the hydrology by phosphate industry water usage and landscape changes and impacts on water quality by discharges of industry wastewater into the waterways Dust was a common air quality problem throughout all mining activities fluoride emissions and radon gas emission were also serious problems Toxic metals and radioactive elements of significant human health problems were Pb Cd Hg Cr As U Th and Ra Most researches agreed that Ra is considered as one of the most toxic radionuclide The nuclide is of further importance as the parent nuclide of the gaseous Rn which along with its solid decay products constitutes a significant source of radiation exposure Scientific researches on mine water drainage and phosphate mining relationship may help to understand the environmental impacts associated with water resource and water quality

Protection Mechanisms of Periphytic Biofilm to Photocatalytic Nanoparticle Exposure

Abstract: Researchers are devoting great effort to combine photocatalytic nanoparticles (PNPs) with biological processes to create efficient environmental purification technologies (i.e., intimately coupled photobiocatalysis). However, little information is available to illuminate the responses of multispecies microbial aggregates against PNP exposure. Periphytic biofilm, as a model multispecies microbial aggregate, was exposed to three different PNPs (CdS, TiO2, and Fe2O3) under xenon lamp irradiation. There were no obvious toxic effects of PNP exposure on periphytic biofilm as biomass, chlorophyll content, and ATPase activity were not negatively impacted. Enhanced production of extracellular polymetric substances (EPS) is the most important protection mechanism of periphytic biofilm against PNPs exposure. Although PNP exposure produced extracellular superoxide radicals and caused intracellular reactive oxygen species (ROS) accumulation in periphytic biofilm, the interaction between EPS and PNPs could mitigate pro...

The stellar kinematics in the solar neighborhood from LAMOST data

Abstract: We use about 200,000 FGK type main-sequence stars from the LAMOST DR1 data to map the local stellar kinematics. With the velocity de-projection technique, we are able to derive the averaged 3 dimensional velocity and velocity ellipsoids using only the line-of-sight velocity for the stars with various effective temperatures within $100 6000$K show a net asymmetric motion of $\sim3 km\,s^{-1}$ in $\langle W\rangle$ compared to the stars with ${T}_{\rm eff}<6000$K. And their azimuthal velocity increases when $|z|$ increases. This peculiar motion in the warmer stars is likely because they are young and not completely relaxed, although other reasons, such as the resonance induced by the central rotating bar or the spiral structures, and the perturbation of the merging dwarf galaxies, can not be ruled out. The derived velocity dispersions and cross terms for the data are approximately consistent with previous studies. We also find that the vertical gradients of $\sigma_{U}$ and $\sigma_V$ are larger than that of $\sigma_W$ . And the vertical gradient of $\sigma_U$ shows clear correlation with ${T}_{\rm eff}$, while the other two do not. Finally, our sample shows vertex deviation of about 11$^\circ$, at $300 < |z| < 500$pc, but roughly zero at $100 < |z| < 300$pc.

microRNA‑199a is able to reverse cisplatin resistance in human ovarian cancer cells through the inhibition of mammalian target of rapamycin

Abstract: microRNAs (miRNAs/miRs) may have a crucial function in tumor metastasis through the regulation of a plethora of signaling pathways. Increasing evidence has shown that miR-199a is important in regulating the tumor metastasis of ovarian cancer, although the precise biological function of miR-199a is unclear at present. In the current study, it was observed that the expression levels of miR-199a were higher in OV2008 cells compared with C13* cells. However, lower levels of mammalian target of rapamycin (mTOR) protein were detected by western blotting in the OV2008 cells compared with the C13* cells. The miR-199a levels were increased in the C13* cells using miR-199a mimics and the mTOR levels were observed to decrease. This may have resulted in a reversal of cisplatin resistance in the C13* cells. To test this hypothesis, the Renilla luciferase reporter gene system was used to analyze the mTOR levels. The results indicated that the expression levels of mTOR were significantly blocked by the increased miR-199a levels. When the miR-199a inhibitor was applied to decrease the miR-199a levels, it was observed that the mTOR expression levels were increased, while cisplatin-induced apoptosis was decreased in the OV2008 cells. The study concludes that miR-199a is able to reverse cisplatin resistance in human ovarian cancer cells through the inhibition of mTOR and that mTOR may be the target of miR-199a during this process.