China Three Gorges University

About: China Three Gorges University is a education organization based out in Yichang, China. It is known for research contribution in the topics: Catalysis & Landslide. The organization has 11161 authors who have published 8011 publications receiving 82224 citations. The organization is also known as: Sanxia Daxue.

Enhancing Proton Conductivity in a 3D Metal–Organic Framework by the Cooperation of Guest [Me2NH2]+ Cations, Water Molecules, and Host Carboxylates

Abstract: A novel proton-conducting MOF material has been synthesized by using 3,3′,4,4′-biphenyltetracarboxylic acid (H4bptc) as organic ligands, which linked to four [Zn(COO)4]2– secondary building units and K ions through four carboxyl groups, and generated a 3D framework [Zn3K2(bptc)3(DMF)2][Me2NH2]4 (JLU-Liu44). The proton-conducting properties of JLU-Liu44 were investigated by impedance spectroscopy. JLU-Liu44 exhibits low conductivity under anhydrous conditions, but the proton conductivity under humidified conditions was significantly enhanced due to the cooperation of guest [Me2NH2]+ cations, water molecules, and host carboxylates. JLU-Liu44 exhibits high proton conductivity of 8.4 × 10–3 S cm–1 at ambient temperature (27 °C) and 98% relative humidity; it is comparable to the most reported proton-conducting MOFs materials under the same condition for powdered sample. The activation energy (Ea) obtained from an Arrhenius plot was 0.25 eV, indicating that the proton conduction behaviors occur through a Grotth...

Isomeric phenylenediacetates as modular tectons for a series of ZnII/CdII coordination polymers incorporating flexible bis(imidazole) co-ligands

Abstract: This work presents a systematic investigation of the reactions of phenylenediacetate isomers with ZnII/CdII salts in the presence of different flexible bis(imidazole) co-ligands. Seven new coordination polymers, namely, {Zn(o-pda)(biim-3)}n (1), {[Cd(o-pda) (biim-5)]·H2O}n (2), {[Zn(m-pda) (biim-4)]·3H2O}n (3), {Cd(m-pda)(biim-6)0.5(H2O)}n (4), {[Cd(p-pda) (biim-3)]·H2O}n (5), {Zn(p-pda) (biim-4)}n (6), and {[Cd(p-pda)(biim-6)]·H2O}n (7) [o/m/p-pda = 1,2/1,3/1,4-phenylenediacetate acid, biim-3 = 1,1′-(1,3-propanedidyl)bis-(imidazole), biim-4 = 1,1′-(1,4- butanedidyl)bis-(imidazole), biim-5 = 1,1′-(1,5-pentanedidyl)bis-(imidazole), biim-6 = 1,1′-(1,6- hexanedidyl)bis-(imidazole)], have been synthesized and characterized by elemental analysis, IR, TG, single crystal X-ray structural determination and powder X-ray diffraction. Complex 1 shows an uncommon 1D achiral chain structure, which contains the right-handed and left-handed helical chains decorated with two zigzag arms. Complexes 2, 3, and 5 display the similar 2D undulating sql layer structures. Interestingly, in 3, the 1D water tape T4(2)6(2), which contains the hexameric water cluster (H2O)6 with a chair-like conformation, assembles these 2D layers to form a 3D framework. In 5, the 2D adjacent hetero-helical layers stack in an –ABĀ– pattern to generate a 3D mesomeric framework. Complex 4 manifests a 2D (3,4)-connected V2O5-type network. Differently from 1–5, complex 6 features a 3D 5-fold interpenetrated dia network, and complex 7 exhibits a 3D (3,5)-connected (42·6)(42·65·83)-fsc framework. A structural comparison of these polymers suggests that different dispositions of the carboxyl sites, diversiform configurations and binding fashions of phenylenediacetate isomers play important roles in the construction of resulting architectures for 1–7, which can also be well regulated by different flexible bis-(imidazole) co-ligands. Moreover, solid-state properties such as thermal stabilities and luminescent properties of 1–7 were also investigated.

Pathophysiological Functions of the lncRNA TUG1.

Abstract: Background Long non-coding RNAs (lncRNAs) with little or no coding capacity are associated with a plethora of cellular functions, participating in various biological processes. Cumulative study of lncRNA provides explanations to the physiological and pathological processes and new perspectives to the diagnosis, prevention, and treatment of some clinical diseases. Long non-coding RNA taurine-upregulated gene 1(TUG1) is one of the first identified lncRNAs associated with human disease, which actively involved in various physiological processes, including regulating genes at epigenetics, transcription, post-transcription, translation, and posttranslation. The aim of this review was to explore the molecular mechanism of TUG1 in various types of human diseases. Methods In this review, we summarized and analyzed the latest findings related to the physiologic and pathophysiological processes of TUG1 in human diseases. The related studies were retrieved and selected the last six years of research articles in PubMed with lncRNA and TUG1 as keywords. Results TUG1 is a valuable lncRNA that its dysregulated expression and regulating the biological processes were found in a variety of human diseases. TUG1 is found to exhibit aberrant expression in a variety of malignancies. Dysregulation of TUG1 has been shown to contribute to proliferation, migration, cell cycle changes, inhibited apoptosis, and drug resistance of cancer cells, which revealed an oncogenic role for this lncRNA, but some reports have shown downregulation of TUG1 in lung cancer samples compared with noncancerous samples. In addition, the molecular and biological functions of TUG1 in physiology and disease (relevant to endocrinology, metabolism, immunology, neurobiology) have also been highlighted. Finally, we discuss the limitations and tremendous diagnostic/therapeutic potential of TUG1 in cancer and other diseases. Conclusion Long non-coding RNA-TUG1 likely served as useful disease biomarkers or therapy targets and effectively applied in different kinds of diseases, such as human cancer and cardiovascular diseases.