China Three Gorges University

About: China Three Gorges University is a education organization based out in Yichang, China. It is known for research contribution in the topics: Catalysis & Landslide. The organization has 11161 authors who have published 8011 publications receiving 82224 citations. The organization is also known as: Sanxia Daxue.

Water Allocation in Transboundary River Basins under Water Scarcity: a Cooperative Bargaining Approach

Abstract: Transboundary river basins are one of the main sources of fresh water which are facing water scarcity. When transboundary water is contested not only the allocation outcomes matter but also the allocation process should possess a certain desirable properties such as flexibility and sustainability. Therefore designing a mechanism that possesses these desirable characteristics and allocates the contested water resource is important as well. This article proposed a water allocation framework by combining the bankruptcy theory with asymmetric Nash bargaining solution concept for solving the water sharing problem in transboundary river basins under scarcity. Furthermore, the allocation framework was applied to the Nile river basin and to a hypothetical water scarce transboundary river basin. The results obtained were then compared with the allocation outcomes from classical bankruptcy allocation rules. The results showed that the proposed method can provide insights which could be useful for obtaining water allocation outcomes which are easier to implement and enforce under water scarce conditions.

Creep degradation mechanism by water-rock interaction in the red-layer soft rock

Abstract: Bank slope stability has become a great concern, while the impoundment of Three Gorges reservoir. The bank slope composed of red-layer soft rock has exhibited distinct deformation and failure. Therefore, a typical red-layer soft rock around Three Gorges reservoir area was selected to demonstrate the process of cyclic changes at the reservoir level and immersion-air-dry cyclic action of water-rock inside hydro-fluctuation belt. To meet the objective of this study, a series of creep tests were conducted on the rock specimens at different water-rock interaction stages. The following points were noticed based on the laboratory results: (1) the creep fracture strength and long-term strength of red-layer soft rock degraded significantly during the process of water-rock interaction. For the first three water-rock interaction circulations, the strength of red-layer soft rock degraded quickly and then gradually became stable. (2) During the creep test, the lateral expansion of red-layer soft rock increased significantly regarding to the number of cycles. (3) The creep curve includes three typical stages at failure stress level—primary (damped) stage, secondary (steady-state) stage, and tertiary (nonlinear accelerated) stage. As the number of cycles increased, the percentage of secondary stage diminished gradually. However, the tertiary stage showed a gradual increment, since the plasticity of the specimens was strengthened by water-rock interaction. (4) The shear failure characteristics of the specimens became highly considerable during the process of water-rock interaction, and there have been a gradual increment of shear rupture zone. (5) The SEM results showed that the specimen microstructure changed its state from dense to loose and porous. The findings of this research provide a good basis for long-term stability analysis of bank slope.

Blockade of NEAT1 represses inflammation response and lipid uptake via modulating miR‐342‐3p in human macrophages THP‐1 cells

Abstract: Atherosclerosis has been recognized as a chronic inflammation process induced by lipid of the vessel wall. Oxidized low-density lipoprotein (ox-LDL) can drive atherosclerosis progression involving macrophages. Recently, long noncoding RNAs (lncRNAs) have been reported to play critical roles in atherosclerosis development. In our current study, we focused on the biological roles of lncRNA NEAT1 in atherosclerosis progress. Here, we found that ox-LDL was able to trigger human macrophages THP-1 cells, a human monocytic cell line, apoptosis in a dose-dependent and time-dependent course. In addition, we observed that NEAT1 was significantly increased in THP-1 cells incubated with ox-LDL and meanwhile miR-342-3p was greatly decreased. Then, NEAT1 was silenced by transfection of small interfering RNA (siRNA) of NEAT1 into THP-1 cells. As exhibited, CD36, oil-red staining levels, total cholesterol (TC), total cholesterol (TG) levels and THP-1 cell apoptosis were obviously repressed by knockdown of NEAT1. Furthermore, inhibition of NEAT1 contributed to the repression of inflammation in vitro. Interleukin 6 (IL-6), IL-1β, cyclooxygenase-2 (COX-2) and tumour necrosis factor-alpha (TNF-α) protein levels were remarkably depressed by NEAT1 siRNA in THP-1 cells. By using bioinformatics analysis, miR-342-3p was predicted as a downstream target of NEAT1 and the correlation between them was confirmed in our study. Moreover, overexpression of miR-342-3p could also greatly suppress inflammation response and lipid uptake in THP-1 cells. Knockdown of NEAT1 and miR-342-3p mimics inhibited lipid uptake in THP-1 cells. In conclusion, we implied that blockade of NEAT1 repressed inflammation response through modulating miR-342-3p in human macrophages THP-1 cells and NEAT1 may offer a promising strategy to treat atherosclerotic cardiovascular diseases.

A3Y2Ge3O12 (A = Ca, Mg): Two novel microwave dielectric ceramics with contrasting τf and Q × f

Abstract: Two garnet-structured microwave dielectric ceramics of A3Y2Ge3O12 (A = Ca, Mg; called CYG and MYG, respectively) were synthesized. CYG was crystallized in a normal cubic garnet structure with Ca2+ fully occupying the dodecahedral (A) site, whereas MYG was an inverse garnet with mixed distribution of Mg2+/Y3+ at the A site. The difference in ionic occupation resulted in anomalies in microwave dielectric properties, with dielectric constant (er) = 14.1, quality factor (Q × f) = 12,600 GHz and positive temperature coefficient of resonant frequency (τf) =120.5 ppm/°C for MYG ceramic and er = 10.8, Q × f = 97,126 GHz and τf = −40.6 ppm/°C for CYG ceramic. The large deviations in measured er from theoretical eth possibly resulted from the garnet structural constraints leading to ‘rattling’ Mg2+ and Y3+ in A site of MYG. Infrared reflectivity spectra analysis revealed ion polarization contributed mostly to the permittivity of both ceramics in microwave frequency ranges.

Finite-time synchronization of drive-response systems via periodically intermittent adaptive control

Abstract: In this paper, the finite-time synchronization between two complex dynamical networks via the periodically intermittent adaptive control and the periodically intermittent feedback control is studied. The finite-time synchronization criteria are derived based on finite-time stability theory, the differential inequality and the analysis technique. Since the traditional synchronization criteria for some models are improved in the convergence time by using the novel periodically intermittent adaptive control and periodically intermittent feedback control, the results of this paper are important. Numerical examples are finally presented to illustrate the effectiveness and correctness of the theoretical results.