China Three Gorges University

About: China Three Gorges University is a education organization based out in Yichang, China. It is known for research contribution in the topics: Catalysis & Landslide. The organization has 11161 authors who have published 8011 publications receiving 82224 citations. The organization is also known as: Sanxia Daxue.

Resveratrol-loaded peptide-hydrogels inhibit scar formation in wound healing through suppressing inflammation.

Abstract: Scar formation seriously affects the repair of damaged skin especially in adults and the excessive inflammation has been considered as the reason. The self-assembled peptide-hydrogels are ideal biomaterials for skin wound healing due to their similar nanostructure to natural extracellular matrix, hydration environment and serving as drug delivery systems. In our study, resveratrol, a polyphenol compound with anti-inflammatory effect, is loaded into peptide-hydrogel (Fmoc-FFGGRGD) to form a wound dressing (Pep/RES). Resveratrol is slowly released from the hydrogel in situ, and the release amount is controlled by the loading amount. The in vitro cell experiments demonstrate that the Pep/RES has no cytotoxicity and can inhibit the production of pro-inflammatory cytokines of macrophages. The Pep/RES hydrogels are used as wound dressings in rat skin damage model. The results suggest that the Pep/RES dressing can accelerate wound healing rate, exhibit well-organized collagen deposition, reduce inflammation and eventually prevent scar formation. The Pep/RES hydrogels supply a potential product to develop new skin wound dressings for the therapy of skin damage.

Unmanned aerial vehicle based remote sensing method for monitoring a steep mountainous slope in the Three Gorges Reservoir, China

Abstract: Monitoring has been considered to be the most effective means of preventing and mitigating geo-hazards. Unmanned aerial vehicle (UAV) based remote sensing has been proven to be a viable method for monitoring relatively flat areas, but has typically encountered challenges on steep mountainous slopes. The Qinglingou Slope, which is located at the head of the Three Gorges Reservoir, China, was selected as a case study, and a UAV-based remote sensing method was applied to monitor this steep mountainous slope. The UAV, which was equipped with a camera, was used to acquire images on May 10 and Sept. 13, 2015. At the same time, a plan for establishing and measuring a detailed network of ground control points (GCPs) and check points was carefully designed and implemented, according to the local conditions. Georeferenced digital surface models (DSMs) and digital orthophotos were obtained by photogrammetric processing. Based on the results, a simple and quick method that identified and quantified slope deformation by calculating and analyzing the changes in the DSMs was developed. The results showed that the UAV-based remote sensing method was rapid, safe and effective, and it could be valuable for monitoring a large number of steep mountainous slopes in the Three Gorges Reservoir.