Institution
Environmental Molecular Sciences Laboratory
Facility•Richland, Washington, United States•
About: Environmental Molecular Sciences Laboratory is a facility organization based out in Richland, Washington, United States. It is known for research contribution in the topics: Mass spectrometry & Ion. The organization has 1471 authors who have published 3010 publications receiving 169961 citations.
Topics: Mass spectrometry, Ion, X-ray photoelectron spectroscopy, Catalysis, Fourier transform ion cyclotron resonance
Papers published on a yearly basis
Papers
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TL;DR: In this article, the second-order quadrupolar line shape for the central transition is split into a comb of sidebands leading to a considerable increase in the sensitivity compared to a conventional QE spectrum.
Abstract: A novel approach to quadrupolar-echo (QE) NMR of half-integer quadrupolar nuclei in static powders is analyzed. By acquisition of the QE spectrum during a Carr−Purcell−Meiboom−Gill (CPMG) train of selective π pulses, the second-order quadrupolar line shape for the central transition is split into a comb of sidebands leading to a considerable increase in the sensitivity compared to a conventional QE spectrum. The applicability of the method for determination of magnitudes and relative orientation of chemical shielding and quadrupolar coupling tensors is examined. Through numerical simulation and iterative fitting of experimental 87Rb (RbClO4 and RbVO3) and 59Co spectra (Co(NH3)5 Cl3), it is demonstrated that the quadrupolar CPMG experiment represents a useful method for studying half-integer quadrupolar nuclei exhibiting large quadrupolar coupling combined with anisotropic chemical shielding interactions. Sensitivity enhancements by a factor of up to about 30 are observed for the samples studied.
322 citations
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TL;DR: In this article, the growth, structure and properties of a two-dimensional carbon nanostructure-carbon nanosheet produced by radio frequency plasma enhanced chemical vapor deposition have been investigated.
320 citations
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TL;DR: A comparison of published calcite dissolution rates measured far from equilibrium at a pH of ∼ 6 and above shows well over an order of magnitude in variation Recently published AFM step velocities extend this range further still.
319 citations
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TL;DR: A probability-based evaluation of false positive rates associated with peptide identifications from three different human proteome samples and two new sets of filtering criteria are proposed to provide an overall confidence of >95% for peptideIdentifications.
Abstract: Large-scale protein identifications from highly complex protein mixtures have recently been achieved using multidimensional liquid chromatography coupled with tandem mass spectrometry (LC/LC−MS/MS) and subsequent database searching with algorithms such as SEQUEST. Here, we describe a probability-based evaluation of false positive rates associated with peptide identifications from three different human proteome samples. Peptides from human plasma, human mammary epithelial cell (HMEC) lysate, and human hepatocyte (Huh)-7.5 cell lysate were separated by strong cation exchange (SCX) chromatography coupled offline with reversed-phase capillary LC−MS/MS analyses. The MS/MS spectra were first analyzed by SEQUEST, searching independently against both normal and sequence-reversed human protein databases, and the false positive rates of peptide identifications for the three proteome samples were then analyzed and compared. The observed false positive rates of peptide identifications for human plasma were significan...
318 citations
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TL;DR: In this paper, the authors show that spontaneous fluctuations in the spectra of immobilized single dye molecules occur on two different timescales: hundreds of milliseconds and tens of seconds, indicating that these fluctuations have two distinct activation energies.
Abstract: RECENT advances in near-field1and far-field2,3 fluorescence microscopy have made it possible to image single molecules and measure their emission3,4 and excitation5 spectra and fluorescence lifetimes3,6–8 at room temperature. These studies have revealed spectral shifts4 and intensity fluctuations6,7, the origins of which are not clear. Here we show that spontaneous fluctuations in the spectra of immobilized single dye molecules occur on two different timescales: hundreds of milliseconds and tens of seconds, indicating that these fluctuations have two distinct activation energies. In addition, we see photoinduced spectral fluctuations on repeated photoexcitation of single molecules. We suggest that all of these fluctuations can be understood as transitions between metastable minima in the molecular potential-energy surface.
316 citations
Authors
Showing all 1477 results
Name | H-index | Papers | Citations |
---|---|---|---|
George M. Whitesides | 240 | 1739 | 269833 |
Yi Cui | 220 | 1015 | 199725 |
Donald G. Truhlar | 165 | 1518 | 157965 |
Ronald W. Davis | 155 | 644 | 151276 |
Richard D. Smith | 140 | 1180 | 79758 |
Yuehe Lin | 118 | 641 | 55399 |
Robert C. Haddon | 112 | 577 | 52712 |
Lai-Sheng Wang | 103 | 576 | 36212 |
Mark H. Engelhard | 103 | 545 | 39864 |
Alex Guenther | 100 | 447 | 45476 |
Gordon E. Brown | 100 | 454 | 32152 |
X. Sunney Xie | 98 | 225 | 44104 |
Jun Li | 98 | 631 | 40958 |
Richard A. Friesner | 97 | 367 | 52729 |
Chongmin Wang | 95 | 451 | 33983 |