Instituto Politécnico Nacional

About: Instituto Politécnico Nacional is a education organization based out in Mexico City, Mexico. It is known for research contribution in the topics: Population & Context (language use). The organization has 43351 authors who have published 63315 publications receiving 938532 citations. The organization is also known as: Instituto Politécnico Nacional & Instituto Politecnico Nacional.

Recent advances in the enantioselective synthesis of beta-amino acids.

Abstract: The introductory section of this review presents some of the currently most compelling beta-amino acid targets, according to their structural types: alpha- and beta-aryl substituted, olefinic and alkynyl, alpha, alpha- and alpha,beta-disubstituted, cyclic and conformationally restricted, fluorine-containing, and phosphonic analogous beta-amino acids. The main section highlights some of the very new (1996-1998), promising methodology for the enantioselective synthesis of beta-amino acids, with especial emphasis on catalytic and enzymatic processes, as well as methods based on "chiral pool", self-regeneration of stereogenic centers , diastereoselective nucleophilic additions to prochiral double bonds, and enantioselective reactions in the presence of chiral additives.

A Modular Code for Real Time Dynamic Simulation of Gas Turbines in Simulink

Abstract: A high-fidelity real-time simulation code based on a lumped, nonlinear representation of gas turbine components is presented. The code is a general-purpose simulation software environment useful for setting up and testing control equipments. The mathematical model and the numerical procedure are specially developed in order to efficiently solve the set of algebraic and ordinary differential equations that describe the dynamic behavior of gas turbine engines. For high-fidelity purposes, the mathematical model takes into account the actual composition of the working gases and the variation of the specific heats with the temperature, including a stage-by-stage model of the air-cooled expansion. The paper presents the model and the adopted solver procedure. The code, developed in Matlab-Simulink using an object-oriented approach, is flexible and can be easily adapted to any kind of plant configuration. Simulation tests of the transients after load rejection have been carried out for a single-shaft heavy-duty gas turbine and a double-shaft aero-derivative industrial engine. Time plots of the main variables that describe the gas turbine dynamic behavior are shown and the results regarding the computational time per time step are discussed.

Measurable Residual Disease by Next-Generation Flow Cytometry in Multiple Myeloma

Abstract: PURPOSE Assessing measurable residual disease (MRD) has become standard with many tumors, but the clinical meaning of MRD in multiple myeloma (MM) remains uncertain, particularly when assessed by n...