Nanyang Technological University

About: Nanyang Technological University is a education organization based out in Singapore, Singapore. It is known for research contribution in the topics: Computer science & Catalysis. The organization has 48003 authors who have published 112815 publications receiving 3294199 citations. The organization is also known as: NTU & Universiti Teknologi Nanyang.

Carbon-Incorporated Nickel–Cobalt Mixed Metal Phosphide Nanoboxes with Enhanced Electrocatalytic Activity for Oxygen Evolution

Abstract: Hollow nanostructures have attracted increasing research interest in electrochemical energy storage and conversion owing to their unique structural features. However, the synthesis of hollow nanostructured metal phosphides, especially nonspherical hollow nanostructures, is rarely reported. Herein, we develop a metal-organic framework (MOF)-based strategy to synthesize carbon incorporated Ni-Co mixed metal phosphide nanoboxes (denoted as NiCoP/C). The oxygen evolution reaction (OER) is selected as a demonstration to investigate the electrochemical performance of the NiCoP/C nanoboxes. For comparison, Ni-Co layered double hydroxide (Ni-Co LDH) and Ni-Co mixed metal phosphide (denoted as NiCoP) nanoboxes have also been synthesized. Benefiting from their structural and compositional merits, the as-synthesized NiCoP/C nanoboxes exhibit excellent electrocatalytic activity and long-term stability for OER.

High-Performance Photothermal Conversion of Narrow-Bandgap Ti2O3 Nanoparticles

Abstract: Ti2 O3 nanoparticles with high performance of photothermal conversion are demonstrated for the first time. Benefiting from the nanosize and narrow-bandgap features, the Ti2 O3 nanoparticles possess strong light absorption and nearly 100% internal solar-thermal conversion efficiency. Furthermore, Ti2 O3 -nanoparticle-based thin film shows potential use in seawater desalination and purification.

Replication and Theory Development in Organizational Science: A Critical Realist Perspective

Abstract: In this article we assess, from a critical realist perspective, the role played by replication in theory development We first present a concise review of critical realism and then reply to the objection that replication is not possible in the social sciences We go on to classify replications into six types along two dimensions Finally, we present a detailed argument for the significance of replication in social science research and propose a multifocal pattern of knowledge accumulation to be integrated with the scattered pattern commonly found in organizational science

Tracking cancer drugs in living cells by thermal profiling of the proteome

Abstract: The thermal stability of proteins can be used to assess ligand binding in living cells. We have generalized this concept by determining the thermal profiles of more than 7000 proteins in human cells by means of mass spectrometry. Monitoring the effects of small-molecule ligands on the profiles delineated more than 50 targets for the kinase inhibitor staurosporine. We identified the heme biosynthesis enzyme ferrochelatase as a target of kinase inhibitors and suggest that its inhibition causes the phototoxicity observed with vemurafenib and alectinib. Thermal shifts were also observed for downstream effectors of drug treatment. In live cells, dasatinib induced shifts in BCR-ABL pathway proteins, including CRK/CRKL. Thermal proteome profiling provides an unbiased measure of drug-target engagement and facilitates identification of markers for drug efficacy and toxicity.

Energy-Optimal Mobile Cloud Computing under Stochastic Wireless Channel

Abstract: This paper provides a theoretical framework of energy-optimal mobile cloud computing under stochastic wireless channel. Our objective is to conserve energy for the mobile device, by optimally executing mobile applications in the mobile device (i.e., mobile execution) or offloading to the cloud (i.e., cloud execution). One can, in the former case sequentially reconfigure the CPU frequency; or in the latter case dynamically vary the data transmission rate to the cloud, in response to the stochastic channel condition. We formulate both scheduling problems as constrained optimization problems, and obtain closed-form solutions for optimal scheduling policies. Furthermore, for the energy-optimal execution strategy of applications with small output data (e.g., CloudAV), we derive a threshold policy, which states that the data consumption rate, defined as the ratio between the data size (L) and the delay constraint (T), is compared to a threshold which depends on both the energy consumption model and the wireless channel model. Finally, numerical results suggest that a significant amount of energy can be saved for the mobile device by optimally offloading mobile applications to the cloud in some cases. Our theoretical framework and numerical investigations will shed lights on system implementation of mobile cloud computing under stochastic wireless channel.