Saint Francis University

About: Saint Francis University is a education organization based out in Loretto, Pennsylvania, United States. It is known for research contribution in the topics: Population & Osteoblast. The organization has 1694 authors who have published 2038 publications receiving 87149 citations.

Hormone Replacement Therapy in Menopause

Abstract: Vasomotor and vaginal symptoms are the hallmark symptoms of menopause. The reported prevalence of vasomotor symptoms is 50–82% in women who experience natural menopause. The occurrence of symptoms increases during perimenopause and usually peaks at the actual onset of menopause.

Visual Evidence of Ischemic Preconditioning During PCI Using 80 Lead ECG Body Surface Mapping

Abstract: Ischemic preconditioning (IPC) is a well-documented phenomenon. Short episodes of sublethal ischemia provide cardioprotective effects for subsequent longer duration ischemic events. Although the exact mechanism of IPC is not yet known, the chemical basis of IPC seems to involve preservation of ATP or collateral vascularization recruitment. In this case report, we present visual evidence of ischemic preconditioning using Heartscape Technologies 80 Lead ECG device. The 80 Lead ECG is described as a body surface mapping modality, converting its inputted 80 lead ECG data into a 3-Dimensional color coded map. The 80 lead ECG device can detect instantaneous ischemic changes. Different studies have been performed to show different clinical and biochemical aspects of IPC. However data regarding direct visual evidence of this phenomenon is lacking. The secondary objective of this study is to show the ability of 80 lead ECG to identify ST-segment elevation and depression during ischemic events. The utility of 80 Lead ECG body surface mapping is enormous when evaluating ischemic events.

A patient with severe hypoxia secondary to a large iatrogenic pulmonary artery to pulmonary vein fistula

Abstract: Pulmonary arteriovenous malformations are uncommon communications between the pulmonary arteries and veins, most commonly associated with hereditary haemorrhagic telangiectasia. They can also be associated with a variety of other conditions, and can be single or multiple. We present a case of a female patient with a history of coronary artery bypass grafting and mitral valve repair, who presented to the hospital with severe hypoxia. She was found to have a large pulmonary artery to superior pulmonary vein fistula that was successfully repaired using a septal occluder. To our knowledge, this is the first case of a large pulmonary artery to superior pulmonary vein fistula following mitral valve repair.

Coronary resting gradients for hemodynamic lesion assessment - The future of coronary physiology?

Abstract: Coronary resting gradient measurements with cut-off values of ≤0.87 and ≥0.93 portend a high degree of certainty with respect to appropriateness of coronary revascularization Less agreement exists in patients in the so called indeterminate "gray zone" Pressure-bounded coronary flow reserve may aid in our understanding of the underlying physiologic principles and facilitate the clinical assessment of these lesions.

Non-Invasive Office Screening Methods

Abstract: Small intestinal bleeding accounts for 5–10% of patients who present with gastrointestinal bleeding and remains a relatively uncommon cause. Unfortunately there are no guidelines or recommendations on screening this population. The office based screening of patients with occult gastrointestinal bleeding includes history and physical. Other strategies are based on screening guidelines for other conditions such as iron deficiency anemia and colorectal cancer screening. In addition patients with incidental findings of fecal occult blood test, or iron deficiency anemia with or without a positive fecal occult blood test may require further work up.