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Institution

University of Toronto

EducationToronto, Ontario, Canada
About: University of Toronto is a education organization based out in Toronto, Ontario, Canada. It is known for research contribution in the topics: Population & Health care. The organization has 126067 authors who have published 294940 publications receiving 13536856 citations. The organization is also known as: UToronto & U of T.


Papers
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Journal ArticleDOI
TL;DR: The fifth edition of the WHO Classification of Tumors of the Central Nervous System (CNS), published in 2021, is the sixth version of the international standard for the classification of brain and spinal cord tumors as mentioned in this paper.
Abstract: The fifth edition of the WHO Classification of Tumors of the Central Nervous System (CNS), published in 2021, is the sixth version of the international standard for the classification of brain and spinal cord tumors. Building on the 2016 updated fourth edition and the work of the Consortium to Inform Molecular and Practical Approaches to CNS Tumor Taxonomy, the 2021 fifth edition introduces major changes that advance the role of molecular diagnostics in CNS tumor classification. At the same time, it remains wedded to other established approaches to tumor diagnosis such as histology and immunohistochemistry. In doing so, the fifth edition establishes some different approaches to both CNS tumor nomenclature and grading and it emphasizes the importance of integrated diagnoses and layered reports. New tumor types and subtypes are introduced, some based on novel diagnostic technologies such as DNA methylome profiling. The present review summarizes the major general changes in the 2021 fifth edition classification and the specific changes in each taxonomic category. It is hoped that this summary provides an overview to facilitate more in-depth exploration of the entire fifth edition of the WHO Classification of Tumors of the Central Nervous System.

2,908 citations

Journal ArticleDOI
TL;DR: New estimates for 2008 of the major causes of death in children younger than 5 years in 193 countries are reported to help to focus national programmes and donor assistance.

2,898 citations

Proceedings ArticleDOI
15 Jun 1988
TL;DR: In this article, simple state-space formulas are presented for a controller solving a standard H∞-problem, where the controller has the same state-dimension as the plant, its computation involves only two Riccati equations, and it has a separation structure reminiscent of classical LQG theory.
Abstract: Simple state-space formulas are presented for a controller solving a standard H∞-problem. The controller has the same state-dimension as the plant, its computation involves only two Riccati equations, and it has a separation structure reminiscent of classical LQG (i.e., H2) theory. This paper is also intended to be of tutorial value, so a standard H2-solution is developed in parallel.

2,875 citations

Journal ArticleDOI
TL;DR: The introduction of a widely acceptable clinical subclassification is strongly advocated, which would allow detailed correlations among serotype, genotype and clinical phenotype to be examined and confirmed in independent cohorts of patients and, thereby, provide a vital foundation for future work.
Abstract: The discovery of a series of genetic and serological markers associated with disease susceptibility and phenotype in inflammatory bowel disease has led to the prospect of an integrated classification system involving clinical, serological and genetic parameters. The Working Party has reviewed current clinical classification systems in Crohn's disease, ulcerative colitis and indeterminate colitis, and provided recommendations for clinical classification in practice. Progress with respect to integrating serological and genetic markers has been examined in detail, and the implications are discussed. While an integrated system is not proposed for clinical use at present, the introduction of a widely acceptable clinical subclassification is strongly advocated, which would allow detailed correlations among serotype, genotype and clinical phenotype to be examined and confirmed in independent cohorts of patients and, thereby, provide a vital foundation for future work.

2,875 citations

Journal ArticleDOI
TL;DR: Will Racism Disappear in Obamerica?
Abstract: Preface for Third Edition of Racism without Racists Chapter 1: The Strange Enigma of Race in Contemporary America Chapter 2: The Central Frames of Color-Blind Racism Chapter 3: The Style of Color Blindness: How to Talk Nasty about Minorities without Sounding Racist Chapter 4: \"I Didn't Get That Job Because of a Black Man\": Color-Blind Racism's Racial Stories Chapter 5: Peeking Inside the (White) House of Color Blindness: The Significance of Whites' Segregation Chapter 6: Are All Whites Refined Archie Bunkers? An Examination of White Racial Progressives Chapter 7: Are Blacks Color Blind, Too? Chapter 8: E Pluribus Unum or the Same Old Perfume in a New Bottle? On the Future of Racial Stratification in the United States Chapter 9: Will Racism Disappear in Obamerica? The Sweet (but Deadly) Enchantment of Colorblindness in Black Face Conclusion

2,865 citations


Authors

Showing all 127245 results

NameH-indexPapersCitations
Gordon H. Guyatt2311620228631
David J. Hunter2131836207050
Rakesh K. Jain2001467177727
Thomas C. Südhof191653118007
Gordon B. Mills1871273186451
George Efstathiou187637156228
John P. A. Ioannidis1851311193612
Paul M. Thompson1832271146736
Yusuke Nakamura1792076160313
Chris Sander178713233287
David R. Williams1782034138789
David L. Kaplan1771944146082
Jasvinder A. Singh1762382223370
Hyun-Chul Kim1764076183227
Deborah J. Cook173907148928
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023504
20221,822
202119,077
202017,303
201915,388
201814,130