Institution
University of Toronto
Education•Toronto, Ontario, Canada•
About: University of Toronto is a education organization based out in Toronto, Ontario, Canada. It is known for research contribution in the topics: Population & Health care. The organization has 126067 authors who have published 294940 publications receiving 13536856 citations. The organization is also known as: UToronto & U of T.
Papers published on a yearly basis
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TL;DR: It is demonstrated that the disordered tails of Ddx4, a primary constituent of nuage or germ granules, form phase-separated organelles both in live cells and in vitro, and proposed that phase separation of disordered proteins containing weakly interacting blocks is a general mechanism for forming regulated, membraneless organlles.
1,307 citations
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TL;DR: In-person and computer-mediated communication are integrated in communities characterized by personalized networking, and social affordances of computer-supported social networks - broader bandwidth, wireless portability, globalized connectivity, personalization - are fostering the movement from door-to-door and place- to-place communities.
Abstract: Computer networks are social networks. Social affordances of computer-supported social networks – broader bandwidth, wireless portability, globalized connectivity, personalization – are fostering the movement from door-to-door and place-to-place communities to person-to-person and role-to-role communities. People connect in social networks rather than in communal groups. In-person and computer-mediated communication are integrated in communities characterized by personalized networking.
Les reseaux informatiques sont des reseaux sociaux. Les possibilites sociales qu’offrent les reseaux sociaux informatises – bande passante plus large, portabilite sans fil, connectivite mondiale, personnalisation – sont en train de favoriser le passage de communautes de porte-a-porte et de lieu-a-lieu vers des communautes d’individu-a-individu et de role-a-role. Ainsi, les gens se lient davantage dans des reseaux sociaux que dans des collectivites. Les communications directes et via l’informatique sont integrees dans des communautes caracterisees par un maillage personnalise.
1,307 citations
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TL;DR: In this article, the authors discuss the properties of perovskites that benefit light emission, review recent progress in perov-skite electroluminescent diodes and optically pumped lasers, and examine the remaining challenges in achieving continuous-wave and electrically driven lasing.
Abstract: The prospects for light-emitting diodes and lasers based on perovskite materials are reviewed. The field of solution-processed semiconductors has made great strides; however, it has yet to enable electrically driven lasers. To achieve this goal, improved materials are required that combine efficient (>50% quantum yield) radiative recombination under high injection, large and balanced charge-carrier mobilities in excess of 10 cm2 V−1 s−1, free-carrier densities greater than 1017 cm−3 and gain coefficients exceeding 104 cm−1. Solid-state perovskites are — in addition to galvanizing the field of solar electricity — showing great promise in photonic sources, and may be the answer to realizing solution-cast laser diodes. Here, we discuss the properties of perovskites that benefit light emission, review recent progress in perovskite electroluminescent diodes and optically pumped lasers, and examine the remaining challenges in achieving continuous-wave and electrically driven lasing.
1,306 citations
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TL;DR: Although screening for rarer atypical forms of diabetic neuropathy may be warranted, DSPN and autonomic neuropathy are the most common forms encountered in practice and the strongest available evidence regarding treatment pertains to these forms.
Abstract: Diabetic neuropathies are the most prevalent chronic complications of diabetes. This heterogeneous group of conditions affects different parts of the nervous system and presents with diverse clinical manifestations. The early recognition and appropriate management of neuropathy in the patient with diabetes is important for a number of reasons:
1. Diabetic neuropathy is a diagnosis of exclusion. Nondiabetic neuropathies may be present in patients with diabetes and may be treatable by specific measures.
2. A number of treatment options exist for symptomatic diabetic neuropathy.
3. Up to 50% of diabetic peripheral neuropathies may be asymptomatic. If not recognized and if preventive foot care is not implemented, patients are at risk for injuries to their insensate feet.
4. Recognition and treatment of autonomic neuropathy may improve symptoms, reduce sequelae, and improve quality of life.
Among the various forms of diabetic neuropathy, distal symmetric polyneuropathy (DSPN) and diabetic autonomic neuropathies, particularly cardiovascular autonomic neuropathy (CAN), are by far the most studied (1–4). There are several atypical forms of diabetic neuropathy as well (1–4). Patients with prediabetes may also develop neuropathies that are similar to diabetic neuropathies (5–10). Table 1 provides a comprehensive classification scheme for the diabetic neuropathies.
View this table:
Table 1
Classification for diabetic neuropathies
Due to a lack of treatments that target the underlying nerve damage, prevention is the key component of diabetes care. Screening for symptoms and signs of diabetic neuropathy is also critical in clinical practice, as it may detect the earliest stages of neuropathy, enabling early intervention. Although screening for rarer atypical forms of diabetic neuropathy may be warranted, DSPN and autonomic neuropathy are the most common forms encountered in practice. The strongest available evidence regarding treatment pertains to these forms.
This Position Statement is based on several recent technical reviews, to which the reader is referred for detailed discussion …
1,306 citations
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TL;DR: This paper surveys recent developments in the design of large-capacity content-addressable memory (CAM) and reviews CAM-design techniques at the circuit level and at the architectural level.
Abstract: We survey recent developments in the design of large-capacity content-addressable memory (CAM). A CAM is a memory that implements the lookup-table function in a single clock cycle using dedicated comparison circuitry. CAMs are especially popular in network routers for packet forwarding and packet classification, but they are also beneficial in a variety of other applications that require high-speed table lookup. The main CAM-design challenge is to reduce power consumption associated with the large amount of parallel active circuitry, without sacrificing speed or memory density. In this paper, we review CAM-design techniques at the circuit level and at the architectural level. At the circuit level, we review low-power matchline sensing techniques and searchline driving approaches. At the architectural level we review three methods for reducing power consumption.
1,305 citations
Authors
Showing all 127245 results
Name | H-index | Papers | Citations |
---|---|---|---|
Gordon H. Guyatt | 231 | 1620 | 228631 |
David J. Hunter | 213 | 1836 | 207050 |
Rakesh K. Jain | 200 | 1467 | 177727 |
Thomas C. Südhof | 191 | 653 | 118007 |
Gordon B. Mills | 187 | 1273 | 186451 |
George Efstathiou | 187 | 637 | 156228 |
John P. A. Ioannidis | 185 | 1311 | 193612 |
Paul M. Thompson | 183 | 2271 | 146736 |
Yusuke Nakamura | 179 | 2076 | 160313 |
Chris Sander | 178 | 713 | 233287 |
David R. Williams | 178 | 2034 | 138789 |
David L. Kaplan | 177 | 1944 | 146082 |
Jasvinder A. Singh | 176 | 2382 | 223370 |
Hyun-Chul Kim | 176 | 4076 | 183227 |
Deborah J. Cook | 173 | 907 | 148928 |