Institution
Wroclaw University of Environmental and Life Sciences
Education•Wrocław, Poland•
About: Wroclaw University of Environmental and Life Sciences is a education organization based out in Wrocław, Poland. It is known for research contribution in the topics: Population & GNSS applications. The organization has 3108 authors who have published 6672 publications receiving 57774 citations.
Topics: Population, GNSS applications, Yarrowia, Soil water, Flavonols
Papers published on a yearly basis
Papers
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TL;DR: Treating MSCs with 5‐Azacytidine can be justified therapeutic intervention, that can slow‐down and even reverse aged‐ related degenerative changes in those cells.
Abstract: Human adipose tissue is a great source of adult mesenchymal stem cells (MSCs) which are recognized from their ability to self-renew and differentiation into multiple lineages. MSCs have promised a vast therapeutic potential in treatment many diseases including tissue injury and immune disorders. However, their regenerative potential profoundly depends on patients' age. Age-related deterioration of MSC is associated with cellular senescence mainly caused by increased DNA methylation status, accumulation of oxidative stress factors and mitochondria dysfunction. We found that DNA methyltransferase (DNMT) inhibitor i.e. 5-Azacytidine (5-AZA) reversed the aged phenotype of MSCs. Proliferation rate of cells cultured with 5-AZA was increased while the accumulation of oxidative stress factors and DNA methylation status were decreased. Simultaneously the mRNA levels of TET proteins involved in demethylation process were elevated in those cells. Moreover, cells treated with 5-AZA displayed reduced reactive oxygen species (ROS) accumulation, ameliorated superoxide dismutase activity and increased BCL-2/BAX ratio in comparison to control group. Our results indicates that, treating MSCs with 5-AZA can be justified therapeutic intervention, that can slow-down and even reverse aged- related degenerative changes in those cells.
77 citations
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TL;DR: In this paper, a mathematical model for simulating and optimising the operation of a large scale solar-wind hybrid coupled with pumped-storage on a district level considering a simplified approach to incorporate grid-related cost.
76 citations
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TL;DR: In this article, a soil polluted from Pb-acid batteries effluent (SPBE) was amended with six different rates (0, 0.5, 1, 2, 4 and 6%) of oxalic acid-activated phosphate rock (OAPR) and their effects on pH, available P and bioavailable Pb concentrations in the rhizosphere and bulk soils of mung bean plant were evaluated.
76 citations
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TL;DR: In this article, the authors present the local approach for ecological footprint assessment and its potential to use for ECC assessment at local (i.e., city) level for the Polish city of Wroclaw in Central Eastern Europe for the year 2016.
75 citations
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TL;DR: In this article, an example of the importance of evapotranspiration in constructed wetlands, with vertical subsurface flow, comparing different methods of treatment efficiency calculations was presented.
74 citations
Authors
Showing all 3137 results
Name | H-index | Papers | Citations |
---|---|---|---|
Jan Oszmiański | 47 | 204 | 8514 |
Aneta Wojdyło | 40 | 182 | 6832 |
Francesco Sansone | 37 | 135 | 4977 |
Guido Viscardi | 35 | 176 | 3832 |
Jan Szopa | 33 | 169 | 4054 |
Henryk Okarma | 33 | 65 | 3264 |
Gaetano Donofrio | 32 | 141 | 3882 |
Andrzej Zalewski | 31 | 85 | 2372 |
Adam Figiel | 30 | 94 | 3309 |
Krzysztof Marycz | 30 | 197 | 3121 |
Waldemar Rymowicz | 29 | 91 | 2560 |
Pierluigi Quagliotto | 28 | 93 | 2330 |
Alfonso Moriana | 28 | 84 | 2489 |
Joost van Hoof | 26 | 95 | 2964 |
Nadia Barbero | 25 | 85 | 1642 |