Institution
Yale University
Education•New Haven, Connecticut, United States•
About: Yale University is a education organization based out in New Haven, Connecticut, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 89824 authors who have published 220665 publications receiving 12834776 citations. The organization is also known as: Yale & Collegiate School.
Topics: Population, Poison control, Medicine, Cancer, Health care
Papers published on a yearly basis
Papers
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TL;DR: This paper examined the investment strategies of 155 mutual funds over the 1975-84 period to determine the extent to which the funds purchased stocks based on their past returns, and determine the relation of this behavior to their observed portfolio performance.
Abstract: We examine the investment strategies of 155 mutual funds over the 1975-84 period to determine the extent to which the funds purchased stocks based on their past returns, and to determine the relation of this behavior to their observed portfolio performance We find that about 77% of these mutual funds were "momentum investors", buying stocks that were past winners; however, they did not systematically sell past losers On average, these "trend-followers" realized significantly better performance than the remaining funds We also find that the mutual funds exhibited herding behavior, and that the tendency of a fund to herd in its trades was strongly correlated with its tendency to buy past winners as well as with its portfolio performance Consistent with the evidence on trend-following, herding into past winners was stronger than herding into past losers
1,685 citations
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TL;DR: Results indicate that Casp9 is a critical upstream activator of the caspase cascade in vivo, as indicated by the absence of Casp3-like cleavage and the restoration of cytochrome c-mediated cleavage after addition of in vitro-translated Casp 9.
1,682 citations
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22 Feb 1982TL;DR: In this paper, a report of a program of coordinated systematic research on variables determining the effects of persuasive communication is presented, with a focus on the effect of persuading messages on the effectiveness of persuasive messages.
Abstract: This is a report of a program of coordinated systematic research on variables determining the effects of persuasive communication.
1,678 citations
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Space Telescope Science Institute1, Johns Hopkins University2, Pennsylvania State University3, Centre national de la recherche scientifique4, European Southern Observatory5, Yale University6, California Institute of Technology7, Goddard Space Flight Center8, Max Planck Society9, University of California, Davis10, European Space Agency11, University of California, Santa Cruz12, University of Arizona13, University of Bonn14, University of California, Berkeley15, University of Oxford16
TL;DR: The GOODS survey as mentioned in this paper is based on multiband imaging data obtained with the Hubble Space Telescope and the Advanced Camera for Surveys (ACS) and covers roughly 320 arcmin2 in the ACS F435W, F606w, F814W, and F850LP bands, divided into two well-studied fields.
Abstract: This special issue of the Astrophysical Journal Letters is dedicated to presenting initial results from the Great Observatories Origins Deep Survey (GOODS) that are primarily, but not exclusively, based on multiband imaging data obtained with the Hubble Space Telescope and the Advanced Camera for Surveys (ACS). The survey covers roughly 320 arcmin2 in the ACS F435W, F606W, F814W, and F850LP bands, divided into two well-studied fields. Existing deep observations from the Chandra X-Ray Observatory and ground-based facilities are supplemented with new, deep imaging in the optical and near-infrared from the European Southern Observatory and from the Kitt Peak National Observatory. Deep observations with the Space Infrared Telescope Facility are scheduled. Reduced data from all facilities are being released worldwide within 3-6 months of acquisition. Together, this data set provides two deep reference fields for studies of distant normal and active galaxies, supernovae, and faint stars in our own Galaxy. This Letter serves to outline the survey strategy and describe the specific data that have been used in the accompanying letters, summarizing the reduction procedures and sensitivity limits.
1,678 citations
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TL;DR: The identification of a mutated putative helicase as the gene product of the WS gene suggests that defective DNA metabolism is involved in the complex process of aging in WS patients.
Abstract: Werner9s syndrome (WS) is an inherited disease with clinical symptoms resembling premature aging. Early susceptibility to a number of major age-related diseases is a key feature of this disorder. The gene responsible for WS (known as WRN ) was identified by positional cloning. The predicted protein is 1432 amino acids in length and shows significant similarity to DNA helicases. Four mutations in WS patients were identified. Two of the mutations are splice-junction mutations, with the predicted result being the exclusion of exons from the final messenger RNA. One of these mutations, which results in a frameshift and a predicted truncated protein, was found in the homozygous state in 60 percent of Japanese WS patients examined. The other two mutations are nonsense mutations. The identification of a mutated putative helicase as the gene product of the WS gene suggests that defective DNA metabolism is involved in the complex process of aging in WS patients.
1,673 citations
Authors
Showing all 91064 results
Name | H-index | Papers | Citations |
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Richard A. Flavell | 231 | 1328 | 205119 |
Eugene Braunwald | 230 | 1711 | 264576 |
Matthias Mann | 221 | 887 | 230213 |
Bruce S. McEwen | 215 | 1163 | 200638 |
Robert J. Lefkowitz | 214 | 860 | 147995 |
Edward Giovannucci | 206 | 1671 | 179875 |
Rakesh K. Jain | 200 | 1467 | 177727 |
Francis S. Collins | 196 | 743 | 250787 |
Lewis C. Cantley | 196 | 748 | 169037 |
Martin White | 196 | 2038 | 232387 |
Ronald Klein | 194 | 1305 | 149140 |
Thomas C. Südhof | 191 | 653 | 118007 |
Michael Rutter | 188 | 676 | 151592 |
David H. Weinberg | 183 | 700 | 171424 |
Douglas R. Green | 182 | 661 | 145944 |