A 15.2-ENOB 5-kHz BW 4.5- $\mu$ W Chopped CT $\Delta\Sigma$ -ADC for Artifact-Tolerant Neural Recording Front Ends

TLDR: A low-power continuous-time delta-sigma analog to digital converter (ADC) is presented, which along with an capacitively-coupled chopper instrumentation amplifier (CCIA) realizes a front end that can digitize neural signals from 1 Hz to 5 kHz in the presence of 200-mV_pp differential artifacts and 700-m V common-mode (CM) artifacts.

Abstract: Implantable closed-loop neural stimulation is desirable for clinical translation and basic neuroscience research. Neural stimulation generates large artifacts at the recording sites, which saturate existing recording front ends. This paper presents a low-power continuous-time delta-sigma analog to digital converter (ADC), which along with an 8 $\times $ gain capacitively-coupled chopper instrumentation amplifier (CCIA), realizes a front end that can digitize neural signals from 1 Hz to 5 kHz in the presence of 200-mVpp differential artifacts and 700-mVpp common-mode (CM) artifacts. A modified loop-filter is used in the ADC along with new linearization techniques to significantly reduce power consumption. Fabricated in 40-nm CMOS, the ADC occupies an area of 0.053 mm2, consumes 4.5 $\mu \text{W}$ from a 1.2-V supply, has an input impedance of 20 $\text{M}\Omega $ and bandwidth (BW) of 5 kHz, and achieves a peak signal to noise and distortion ratio (SNDR) of 93.5 dB for a 1.77- $\text{V}_{\mathrm {pp}}$ differential input at 1 kHz. The ADC’s figure of merit (FOM) (using SNDR) is 184 dB, which is 6 dB higher than the state of the art in high-resolution ADCs. The complete front end occupies an area of 0.113 mm2, consumes 7.3 $\mu \text{W}$ from a 1.2-V supply, has a dc input impedance of 1.5 $\text{G}\Omega $ , input-referred noise of 6.35 $\mu \text{V}_{\mathrm {rms}}$ in 1 Hz–5 kHz, and total harmonic distortion of −81 dB for a 200-mVpp input at 1 kHz, and is immune to 700-mVpp CM interference. Compared to front ends intended for closed-loop neural recording, this paper improves the linear input range by 2 $\times $ , the signal BW by 10 $\times $ , the dynamic range by 12.6 dB, the FOM by 12.4 dB and remains immune to large CM interference while maintaining comparable power, area, and noise performance.