A 3D-ACEK/SERS system for highly efficient and selectable electrokinetic bacteria concentration/detection/ antibiotic-susceptibility-test on whole blood.
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TLDR
In this paper, a three dimensional alternative current electrokinetic/surface enhanced Raman scattering (3D-ACEK/SERS) microchip was used to identify bacterial species and determine antibiotic susceptibilities of the bacteria rapidly.About:
This article is published in Biosensors and Bioelectronics.The article was published on 2022-02-01 and is currently open access. It has received 10 citations till now. The article focuses on the topics: Electrokinetic phenomena & Dielectrophoresis.read more
Citations
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Journal ArticleDOI
SERS-based antibiotic susceptibility testing: Towards point-of-care clinical diagnosis.
Nicoleta Elena Dina,Muhammad Ali Tahir,Sadia Zafar Bajwa,Imran Amin,Ventsislav K. Valev,Li‐yun Zhang +5 more
TL;DR: In this paper , surface-enhanced Raman scattering (SERS) is used for detecting emerging antibiotic resistant bacteria and for antibiotic susceptibility testing (AST) in clinical point-of-care (PoC) devices.
Journal ArticleDOI
Label-free microfluidic cell sorting and detection for rapid blood analysis.
Nan Lu,Hui Min Tay,Chayakorn Petchakup,Linwei He,Lingyan Gong,Kaythaya Maw,Sheng Yuan Leong,Wan Wei Lok,HongYao Ong,Ruya Guo,King Ho Holden Li,Han Wei Hou +11 more
TL;DR: Label-free single cell analysis of intrinsic cell morphology, spectrochemical properties, dielectric parameters and biophysical characteristics as novel blood-based biomarkers are presented in this paper , where the authors highlight research efforts that combine label-free microfluidics with machine learning approaches to enhance detection sensitivity and specificity in clinical studies, as well as innovative micro-fluidic solutions which are capable of fully integrated and label free blood cell sorting and analysis.
Journal ArticleDOI
Recent Progress of Surface-Enhanced Raman Spectroscopy for Bacteria Detection
TL;DR: Wang et al. as discussed by the authors reviewed the latest advances in surface-enhanced Raman spectroscopy (SERS) technology in the field of bacteria analysis and gave an outlook on the future development and trends of SERS in point-of-care diagnoses of bacterial infections.
Journal ArticleDOI
Electrokinetics in antimicrobial resistance analysis: A review
TL;DR: In this article , a review of electrokinetic (EK) bacteria manipulation, including enrichment and separation, is presented, focusing on the rapid electric-based minimum inhibitory concentration measurement.
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Detection of stx2 from Shiga toxin-producing Escherichia coli (STEC) by a surface enhanced Raman spectroscopy (SERS) sensor using recycled silicon chips
TL;DR: In this paper , a selective, cost-efficient, and highly sensitive Ag nanostructure surface enhanced Raman Spectroscopy (SERS) sensor was developed as a methodological approach to rapidly detect a targetss-DNA (stx2) in STEC (Shiga toxin-producing Escherichia coli).
References
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Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock.
Anand Kumar,Daniel Roberts,Kenneth E. Wood,Bruce Light,Joseph E. Parrillo,Satendra Sharma,Robert Suppes,Daniel Feinstein,Sergio Zanotti,Leo Taiberg,David A. Gurka,Aseem Kumar,Mary Cheang +12 more
TL;DR: Effective antimicrobial administration within the first hour of documented hypotension was associated with increased survival to hospital discharge in adult patients with septic shock.
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Correction: Corrigendum: The Serum Profile of Hypercytokinemia Factors Identified in H7N9-Infected Patients can Predict Fatal Outcomes
Jing Guo,Fengming Huang,Jun Liu,Yu Chen,Wei Wang,Bin Cao,Zhen Zou,Song Liu,Jingcao Pan,Changjun Bao,Mei Zeng,Haixia Xiao,Hainv Gao,Shigui Yang,Yan Zhao,Qiang Liu,Huandi Zhou,Jingdong Zhu,Xiaoli Liu,Weifeng Liang,Yida Yang,Shufa Zheng,Jiezuan Yang,Hongyan Diao,Kunkai Su,Li Shao,Hongcui Cao,Ying Wu,Min Zhao,Shuguang Tan,Hui Li,Xiaoqing Xu,Chunmei Wang,Jianmin Zhang,Li Wang,Jianwei Wang,Jun Xu,Dangsheng Li,Nanshan Zhong,Xuetao Cao,George F. Gao,Lanjuan Li,Chengyu Jiang +42 more
TL;DR: This Article contains typographical errors in Table 2 where ‘Week 2 (N = 32)’ was incorrectly given as ‘week (n’=2’.
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Unravelling the Role of O-glycans in Influenza A Virus Infection
Juliane Mayr,Kam Lau,Jimmy C. C. Lai,Ivan A. Gagarinov,Yun Shi,Sarah McAtamney,Renee W. Y. Chan,John M. Nicholls,Mark von Itzstein,Thomas Haselhorst +9 more
TL;DR: It is suggested that sialylated Galβ(1,3)GalNAc as O-glycan core 1 glycoforms are involved in the influenza A virus life cycle and play a particularly crucial role during infection of HPAI strains.
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Discrimination of Bacteria Using Surface-Enhanced Raman Spectroscopy
Roger M. Jarvis,Royston Goodacre +1 more
TL;DR: This is believed to be the first report showing bacterial discrimination using SERS, and the resultant ordination plots and dendrograms showed correct groupings for these organisms, including discrimination to strain level for a sample group of Escherichia coli.
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AC Electric-Field-Induced Fluid Flow in Microelectrodes.
TL;DR: Measurements of the fluid velocity as a function of frequency and position across the electrode indicate that the flow occurs due to electroosmotic stress arising from the interaction of the electric field and the electrical double layer on the electrodes.