Adaptive introgression in animals: examples and comparison to new mutation and standing variation as sources of adaptive variation.
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TLDR
The various attributes of these three potential sources of adaptive variation are compared, including balancing selection for multiple alleles for major histocompatibility complex (MHC), S and csd genes, pesticide resistance in mice, black colour in wolves and white colour in coyotes, Neanderthal or Denisovan ancestry in humans, and mimicry genes in Heliconius butterflies are examined.Abstract:
Adaptive genetic variation has been thought to originate primarily from either new mutation or standing variation. Another potential source of adaptive variation is adaptive variants from other (donor) species that are introgressed into the (recipient) species, termed adaptive introgression. Here, the various attributes of these three potential sources of adaptive variation are compared. For example, the rate of adaptive change is generally thought to be faster from standing variation, slower from mutation and potentially intermediate from adaptive introgression. Additionally, the higher initial frequency of adaptive variation from standing variation and lower initial frequency from mutation might result in a higher probability of fixation of the adaptive variants for standing variation. Adaptive variation from introgression might have higher initial frequency than new adaptive mutations but lower than that from standing variation, again making the impact of adaptive introgression variation potentially intermediate. Adaptive introgressive variants might have multiple changes within a gene and affect multiple loci, an advantage also potentially found for adaptive standing variation but not for new adaptive mutants. The processes that might produce a common variant in two taxa, convergence, trans-species polymorphism from incomplete lineage sorting or from balancing selection and adaptive introgression, are also compared. Finally, potential examples of adaptive introgression in animals, including balancing selection for multiple alleles for major histocompatibility complex (MHC), S and csd genes, pesticide resistance in mice, black colour in wolves and white colour in coyotes, Neanderthal or Denisovan ancestry in humans, mimicry genes in Heliconius butterflies, beak traits in Darwin's finches, yellow skin in chickens and non-native ancestry in an endangered native salamander, are examined.read more
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References
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Book
The Neutral Theory of Molecular Evolution
TL;DR: The neutral theory as discussed by the authors states that the great majority of evolutionary changes at the molecular level are caused not by Darwinian selection but by random drift of selectively neutral mutants, which has caused controversy ever since.
Journal ArticleDOI
A Draft Sequence of the Neandertal Genome
Richard E. Green,Johannes Krause,Adrian W. Briggs,Tomislav Maricic,Udo Stenzel,Martin Kircher,Nick Patterson,Heng Li,Weiwei Zhai,Markus Hsi-Yang Fritz,Nancy F. Hansen,Eric Durand,Anna-Sapfo Malaspinas,Jeffrey D. Jensen,Tomas Marques-Bonet,Tomas Marques-Bonet,Can Alkan,Kay Prüfer,Matthias Meyer,Hernán A. Burbano,Jeffrey M. Good,Jeffrey M. Good,Rigo Schultz,Ayinuer Aximu-Petri,Anne Butthof,Barbara Höber,Barbara Höffner,Madien Siegemund,Antje Weihmann,Chad Nusbaum,Eric S. Lander,Carsten Russ,Nathaniel Novod,Jason P. Affourtit,Michael Egholm,Christine Verna,Pavao Rudan,Dejana Brajković,Željko Kućan,Ivan Gušić,Vladimir B. Doronichev,Liubov V. Golovanova,Carles Lalueza-Fox,Marco de la Rasilla,Javier Fortea,Antonio Rosas,Ralf Schmitz,Philip L. F. Johnson,Evan E. Eichler,Daniel Falush,Ewan Birney,James C. Mullikin,Montgomery Slatkin,Rasmus Nielsen,Janet Kelso,Michael Lachmann,David Reich,David Reich,Svante Pääbo +58 more
TL;DR: The genomic data suggest that Neandertals mixed with modern human ancestors some 120,000 years ago, leaving traces of Ne andertal DNA in contemporary humans, suggesting that gene flow from Neand Bertals into the ancestors of non-Africans occurred before the divergence of Eurasian groups from each other.
Journal ArticleDOI
The neutral theory of molecular evolution.
TL;DR: It is stated that these sequences differed in the cytochromes c of various species to an extent that seemed unnecessary from the standpoint of their function.
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