Adaptive introgression in animals: examples and comparison to new mutation and standing variation as sources of adaptive variation.
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TLDR
The various attributes of these three potential sources of adaptive variation are compared, including balancing selection for multiple alleles for major histocompatibility complex (MHC), S and csd genes, pesticide resistance in mice, black colour in wolves and white colour in coyotes, Neanderthal or Denisovan ancestry in humans, and mimicry genes in Heliconius butterflies are examined.Abstract:
Adaptive genetic variation has been thought to originate primarily from either new mutation or standing variation. Another potential source of adaptive variation is adaptive variants from other (donor) species that are introgressed into the (recipient) species, termed adaptive introgression. Here, the various attributes of these three potential sources of adaptive variation are compared. For example, the rate of adaptive change is generally thought to be faster from standing variation, slower from mutation and potentially intermediate from adaptive introgression. Additionally, the higher initial frequency of adaptive variation from standing variation and lower initial frequency from mutation might result in a higher probability of fixation of the adaptive variants for standing variation. Adaptive variation from introgression might have higher initial frequency than new adaptive mutations but lower than that from standing variation, again making the impact of adaptive introgression variation potentially intermediate. Adaptive introgressive variants might have multiple changes within a gene and affect multiple loci, an advantage also potentially found for adaptive standing variation but not for new adaptive mutants. The processes that might produce a common variant in two taxa, convergence, trans-species polymorphism from incomplete lineage sorting or from balancing selection and adaptive introgression, are also compared. Finally, potential examples of adaptive introgression in animals, including balancing selection for multiple alleles for major histocompatibility complex (MHC), S and csd genes, pesticide resistance in mice, black colour in wolves and white colour in coyotes, Neanderthal or Denisovan ancestry in humans, mimicry genes in Heliconius butterflies, beak traits in Darwin's finches, yellow skin in chickens and non-native ancestry in an endangered native salamander, are examined.read more
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Evidence for archaic adaptive introgression in humans
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How reticulated are species
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The evolutionary origins of pesticide resistance.
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References
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How and Why Species Multiply: The Radiation of Darwin's Finches.Princeton Series in Evolutionary Biology. ByPeter R. Grantand, B. Rosemary Grant. Princeton (New Jersey): Princeton University Press. $35.00. xxi + 218 p. + 31 pl.; ill.; author and subject indexes. 978‐0‐691‐13360‐7. 2008.
Journal ArticleDOI
Introgression of wing pattern alleles and speciation via homoploid hybridization in Heliconius butterflies: a review of evidence from the genome.
TL;DR: The theory and data supporting various aspects of the apparent paradox of ‘magic trait’ introgression are reviewed, with emphasis on population genomic comparisons of Heliconius melpomene and its close relatives.
Journal ArticleDOI
Peak and Persistent Excess of Genetic Diversity Following an Abrupt Migration Increase
TL;DR: It is demonstrated that during transient dynamics, genetic diversity can reach unexpectedly high values that can be maintained over thousands of generations.
Journal ArticleDOI
Breakdown of isolation mechanisms in two species of captive junglefowl (gallus gallus and gallus sonneratii).
TL;DR: The methods by which natural breeding between the two species was effected, and information is provided on the fertility of the hybrids, are presented.
Journal ArticleDOI
Distribution and frequency of VKORC1 sequence variants conferring resistance to anticoagulants in Mus musculus
Hans-Joachim Pelz,Simone Rost,Elisabeth Müller,Alexandra Esther,Rainer G. Ulrich,Clemens R. Müller +5 more
TL;DR: An evaluation of published data revealed that the three most frequently found sequence variants are associated with a substantial loss of rodenticide efficacy of first-generation anticoagulants, as well as the second-generation compound bromadiolone and most probably also difenacoum.
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