Journal ArticleDOI
Age-Specific Normal Reference Range for Serum Anti-Müllerian Hormone in Healthy Chinese Han Women: A nationwide Population-Based Study
Xiaofang Du,Ting Ding,Hanwang Zhang,Cuilian Zhang,Wenmin Ma,Ying Zhong,Wenyu Qu,Jie Zheng,Yi Liu,Zhiying Li,Kecheng Huang,Song Deng,Lanfang Ma,Jun Yang,Jingjing Jiang,Shuhong Yang,Jia Huang,Meng Wu,Li Fang,Yunping Lu,Aiyue Luo,Shixuan Wang +21 more
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TLDR
The normal reference ranges for serum AMH levels in a large population-based sample of healthy Chinese women are determined and relationship between AMH and other variables remain unchanged except for PRL, which was not significantly correlated with AMH Levels after controlling for both age and BMI.Abstract:
Background:The increasing use of anti-Mullerian hormone (AMH) in clinic has raised concerns regarding the reliable reference range for this test. However, the reference range for AMH in normal Chin...read more
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Anti-Müllerian Hormone and Ovarian Reserve: Update on Assessing Ovarian Function
TL;DR: Serum AMH levels are used in individualized follicle-stimulating hormone dosing protocols and may predict the risk of poor response or ovarian hyperstimulation syndrome but has limited value in predicting ongoing pregnancy.
Journal ArticleDOI
Circular RNA expression profiling of human granulosa cells during maternal aging reveals novel transcripts associated with assisted reproductive technology outcomes.
Jing Cheng,Jia Huang,Suzhen Yuan,Su Zhou,Wei Yan,Wei Shen,Yun Chen,Xi Xia,Aiyue Luo,Da Zhu,Shixuan Wang +10 more
TL;DR: Bioinformatics analysis revealed that both circRNAs were potentially involved in glucose metabolism, mitotic cell cycle, and ovarian steroidogenesis, and might be potential indicators of compromised follicular micro-environment which could be used to predict IVF prognosis, and improve female infertility management.
Journal ArticleDOI
Circulatory microRNA 23a and microRNA 23b and polycystic ovary syndrome (PCOS): the effects of body mass index and sex hormones in an Eastern Han Chinese population
Weixi Xiong,Weixi Xiong,Ying Lin,Lili Xu,Amin Tamadon,Shien Zou,Fubo Tian,Ruijin Shao,Xin Li,Yi Feng +9 more
TL;DR: Both reduced levels and discordance between the expressions of miR-23a/b were observed in the women with PCOS and miR/b was affected from testosterone and BMI, reversely, therefore, miR -23a alteration in contrast with miB-23b is a better indicator for evaluation of PCOS than the miRNAs.
Journal ArticleDOI
Demographic, lifestyle, and other factors in relation to antimüllerian hormone levels in mostly late premenopausal women
Seungyoun Jung,Naomi E. Allen,Alan A. Arslan,Laura Baglietto,Laura Baglietto,Louise A. Brinton,Brian L. Egleston,Roni T. Falk,Renée T. Fortner,Kathy J. Helzlsouer,Kathy J. Helzlsouer,Annika Idahl,Rudolph Kaaks,Eva Lundin,Melissa A. Merritt,Charlotte Onland-Moret,Sabina Rinaldi,María José Sánchez,Sabina Sieri,Helena Schock,Xiao-Ou Shu,Patrick M. Sluss,Paul N. Staats,Ruth C. Travis,Anne Tjønneland,Antonia Trichopoulou,Shelley S. Tworoger,Kala Visvanathan,Vittorio Krogh,Elisabete Weiderpass,Anne Zeleniuch-Jacquotte,Wei Zheng,Joanne F. Dorgan +32 more
TL;DR: Among premenopausal women, lower AMH concentrations are associated with older age, a younger age at menarche, and currently using oral contraceptives, suggesting these factors are related to a lower number or decreased secretory activity of ovarian follicles.
Journal ArticleDOI
Ethnic discordance in serum anti-Müllerian hormone in healthy women: a population study from China and Europe.
Scott M. Nelson,Sun Aijun,Qui Ling,Xu Tengda,Xue Wei,Deng Yan,Wang Yanfang,Tian Zenghui,Chen Xinqi,Abigail Fraser,Gemma L. Clayton +10 more
TL;DR: There were independent effects of age and ethnicity on serum AMH concentrations, with Chinese women having a substantially lower AMH in adult life than their European counterparts from age 25 onwards.
References
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Journal ArticleDOI
The variability of female reproductive ageing
TL;DR: Age at last birth in natural fertility populations, which marks the end of female fertility, shows an identically wide variation as age at menopause, but occurs on average 10 years earlier than this, given the high heritability for age atMenopause.
Journal ArticleDOI
Serum anti-mullerian hormone levels: a novel measure of ovarian reserve
I A J van Rooij,Frank J.M. Broekmans,E.R. te Velde,Bart C.J.M. Fauser,László F.J.M.M Bancsi,F. H. De Jong,Axel P. N. Themmen +6 more
TL;DR: Poor response in IVF, indicative of a diminished ovarian reserve, is associated with reduced baseline serum AMH concentrations, and it appears that AMH can be used as a marker for ovarian ageing.
Journal ArticleDOI
Control of primordial follicle recruitment by anti-Müllerian hormone in the mouse ovary.
Alexandra L. L. Durlinger,Piet Kramer,Bas Karels,Frank H. de Jong,Jan Th. J. Uilenbroek,J. Anton Grootegoed,Axel P. N. Themmen +6 more
TL;DR: It is found that ovaries of 25-day- and 4-month-old AMH null females, compared to those of wild-type females, contain more preantral and small antral follicles, and AMH plays an important role inPrimordial follicle recruitment, such that more primordial follicles are recruited in AMHnull mice than in wild- type mice.
Journal ArticleDOI
Anti-Müllerian Hormone Attenuates the Effects of FSH on Follicle Development in the Mouse Ovary
Alexandra L. L. Durlinger,Maria J. G. Gruijters,Piet Kramer,Bas Karels,T. Rajendra Kumar,Martin M. Matzuk,Ursula M. Rose,Frank H. de Jong,Jan Th. J. Uilenbroek,J. Anton Grootegoed,Axel P. N. Themmen +10 more
TL;DR: It was shown that FSH-stimulated preantral follicle growth is attenuated in the presence of AMH, and in immature AMH-deficient females, more follicles start to grow under the influence of exogenous FSH than in their wild-type littermates.
Journal Article
The guidelines for prevention and control of overweight and obesity in Chinese adults.
Chunming Chen,Frank C Lu +1 more
TL;DR: The hemorrhagic environment in vivo induces NSCs to differentiate mainly into astrocytes while co-culture with Schwann cells in vitro induce the majority of NSCS to differentiate into neural cells.