Journal ArticleDOI
An analysis of rat prefrontal cortex in mediating executive function.
TLDR
The data suggest that there is subregional specificity within the PFC of rats, monkey and humans and there are parallel cognitive functions of the different subregions of the P FC in rats, monkeys and humans.About:
This article is published in Neurobiology of Learning and Memory.The article was published on 2011-10-01. It has received 342 citations till now. The article focuses on the topics: Working memory & Executive functions.read more
Citations
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Children with Attention Deficit Hyperactivity Disorder Are More Likely to Fail Growth Hormone Stimulation Testing than Children without Attention Deficit Hyperactivity Disorder: A Retrospective Chart Review
Ksenia Tonyushkina,Obiageli Obi,Paul Visintainer,Victoria Valentine Cobb,E. Reiter,Holley Allen +5 more
TL;DR: In this article , the authors evaluate whether children with ADHD and short stature or growth failure are more likely to fail growth hormone stimulation testing compared to children without ADHD, and they found that the same trend persisted after regression analysis with adjustment for sex and stratification by age and effect was more robust in the older group.
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Where Actions Meet Outcomes: Medial Prefrontal Cortex, Central Thalamus, and the Basal Ganglia
TL;DR: The role of the medial prefrontal cortex (mPFC) in goal-directed behavior has been investigated in this paper , where electrophysiological recordings of mPFC neurons in rats performing delayed non-matching-to position (DNMTP) and other complex decision-making tasks have revealed populations of neurons with activity related to actions and outcomes.
Role of Rat Neuronal Oscillations in Acquisition and Disruption of Working Memory with Acute Ethanol
TL;DR: This work investigates the relationships between theta and gamma rhythms in the hippocampus, a model for working memory used in animal models, and the role of these rhythms in human development.
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Potential Inflammatory Biomarker in Patients with Attention Deficit Hyperactivity Disorder
TL;DR: The kynurenine pathway (KP) contains a set of enzymatic reactions involved in tryptophan (TRP) degradation, which is known to be associated with the risk of developing ADHD as mentioned in this paper .
References
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Journal ArticleDOI
An integrative theory of prefrontal cortex function
Earl K. Miller,Jonathan D. Cohen +1 more
TL;DR: It is proposed that cognitive control stems from the active maintenance of patterns of activity in the prefrontal cortex that represent goals and the means to achieve them, which provide bias signals to other brain structures whose net effect is to guide the flow of activity along neural pathways that establish the proper mappings between inputs, internal states, and outputs needed to perform a given task.
Journal ArticleDOI
Insensitivity to future consequences following damage to human prefrontal cortex
TL;DR: Using a novel task which simulates real-life decision-making in the way it factors uncertainty of premises and outcomes, as well as reward and punishment, it is found that prefrontal patients are oblivious to the future consequences of their actions, and seem to be guided by immediate prospects only.
Book
The Cognitive Neurosciences
TL;DR: The fourth edition of The Cognitive Neurosciences continues to chart new directions in the study of the biologic underpinnings of complex cognition -the relationship between the structural and physiological mechanisms of the nervous system and the psychological reality of the mind as discussed by the authors.
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Specific impairments of planning
TL;DR: An information-processing model is outlined that predicts that performance on non-routine tasks can be impaired independently of performance on routine tasks, related to views on frontal lobe functions, particularly those of Luria.
Journal ArticleDOI
Separate Neural Systems Value Immediate and Delayed Monetary Rewards
TL;DR: The authors examined the neural correlates of time discounting while subjects made a series of choices between monetary reward options that varied by delay to delivery and demonstrated that two separate systems are involved in such decisions.